Asz1 ELISA Kit for Mouse(Mus musculus) | EIAab.comAsz1 ELISA Kit for Mouse(Mus musculus)

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Asz1 (Gene name),

Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Protein name ), ASZ1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Asz1(Gasz);

Protein name:

Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1;

Alternative:

Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with DDX4, PIWIL1, RANBP9 and TDRD1.

Function:

Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

Subcellular Location:

Cytoplasm Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon during meiosis. Specifically localizes to pi-bodies, a subset of the nuage which contains primary piRNAs.

Protein Attributes:

Sequence length:

475

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

475:

LKRSAVTVCG | FGLLLFIGKL | TLQRK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q8VD46

KEGG:

mmu:74068

SMR:

Q8VD46

Pfam:

PF12796

UniGene:

Mm.73091

Uniprot:

Q8VD46

FOR

ELISA Kit for Mouse Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1

CLIA Kit for Mouse Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1

Polyclonal Antibody for Mouse Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1

Monoclonal Antibody for Mouse Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1

Protein for Mouse Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Identification of Gasz, an evolutionarily conserved gene expressed exclusively in germ cells and encoding a protein with four ankyrin repeats, a sterile-alpha motif, and a basic leucine zipper."
Yan W. , Rajkovic A. , Viveiros M.M. , Burns K.H. , Eppig J.J. , Matzuk M.M.
Mol. Endocrinol.16:1168-1184(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
strain: 129/Sv.
tissue: Ovary.
tissue: Testis.
2.

"Comparative genomic sequence analysis of the human and mouse cystic fibrosis transmembrane conductance regulator genes."
Ellsworth R.E. , Jamison D.C. , Touchman J.W. , Chissoe S.L. , Braden Maduro V.V. , Bouffard G.G. , Dietrich N.L. , Beckstrom-Sternberg S.M. , Iyer L.M. , Weintraub L.A. , Cotton M. , Courtney L. , Edwards J. , Maupin R. , Ozersky P. , Rohlfing T. , Wohldmann P. , Miner T. , more...
Proc. Natl. Acad. Sci. U.S.A.97:1172-1177(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
4.

Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6J.
tissue: Embryo.
6.

"GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline."
Ma L. , Buchold G.M. , Greenbaum M.P. , Roy A. , Burns K.H. , Zhu H. , Han D.Y. , Harris R.A. , Coarfa C. , Gunaratne P.H. , Yan W. , Matzuk M.M.
PLoS Genet.5:E1000635-E1000635(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;DISRUPTION PHENOTYPE;INTERACTION WITH DDX4; PIWIL1; RANBP9 AND TDRD1

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