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Index > Protein center > Atp2a1(Gene name) > Rat
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  • Atp2a1 (Gene name),
  • Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (Protein name ),  AT2A1_RAT from NCBI database.
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  • General Annotation
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  • Gene name:
    Atp2a1;
    Protein name:
    Sarcoplasmic/endoplasmic reticulum calcium ATPase 1(SERCA1;SR Ca(2+)-ATPase 1);
    Alternative:
    Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform;Calcium pump 1;Endoplasmic reticulum class 1/2 Ca(2+) ATPase;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Associated with sarcolipin (SLN) and phospholamban (PLN).
    Function:
    This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.
    Subcellular Location:
    Endoplasmic reticulum membrane Multi-pass membrane protein Sarcoplasmic reticulum membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    994
    Sequence:
    50:
    MEAAHSKSTE | ECLSYFGVSE | TTGLTPDQVK | RHLEKYGPNE | LPAEEGKSLW | 
    100:
    ELVVEQFEDL | LVRILLLAAC | ISFVLAWFEE | GEETVTAFVE | PFVILLILIA | 
    150:
    NAIVGVWQER | NAENAIEALK | EYEPEMGKVY | RADRKSVQRI | KARDIVPGDI | 
    200:
    VEVAVGDKVP | ADIRILSIKS | TTLRVDQSIL | TGESVSVIKH | TDPVPDPRAV | 
    250:
    NQDKKNMLFS | GTNIAAGKAV | GIVATTGVST | EIGKIRDQMA | ATEQDKTPLQ | 
    300:
    QKLDEFGEQL | SKVISLICVA | VWLINIGHFN | DPVHGGSWFR | GAIYYFKIAV | 
    350:
    ALAVAAIPEG | LPAVITTCLA | LGTRRMAKKN | AIVRSLPSVE | TLGCTSVICS | 
    400:
    DKTGTLTTNQ | MSVCKMFIID | KVDGDICSLN | EFSITGSTYA | PEGEVLKNDK | 
    450:
    PVRAGQYDGL | VELATICALC | NDSSLDFNET | KGVYEKVGEA | TETALTTLVE | 
    500:
    KMNVFNTEVR | SLSKVERANA | CNSVIRQLMK | KEFTLEFSRD | RKSMSVYCSP | 
    550:
    AKSSRAAVGN | KMFVKGAPEG | VIDRCNYVRV | GTTRVPLTGP | VKEKIMSVIK | 
    600:
    EWGTGRDTLR | CLALATRDTP | PKREEMVLDD | SAKFMEYEMD | LTFVGVVGML | 
    650:
    DPPRKEVTGS | IQLCRDAGIR | VIMITGDNKG | TAIAICRRIG | IFSENEEVAD | 
    700:
    RAYTGREFDD | LPLAEQREAC | RRACCFARVE | PSHKSKIVEY | LQSYDEITAM | 
    750:
    TGDGVNDAPA | LKKAEIGIAM | GSGTAVAKTA | SEMVLADDNF | STIVAAVEEG | 
    800:
    RAIYNNMKQF | IRYLISSNVG | EVVCIFLTAA | LGLPEALIPV | QLLWVNLVTD | 
    850:
    GLPATALGFN | PPDLDIMDRP | PRSPKEPLIS | GWLFFRYMAI | GGYVGAATVG | 
    900:
    AAAWWFLYAE | DGPHVSYHQL | THFMQCTEHN | PEFDGLDCEV | FEAPEPMTMA | 
    950:
    LSVLVTIEMC | NALNSLSENQ | SLLRMPPWVN | IWLLGSICLS | MSLHFLILYV | 
    994:
    DPLPMIFKLR | ALDFTQWLMV | LKISLPVIGL | DELLKFIARN | YLEG
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    Pfam:
    UniGene:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat SERCA1
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    E15014h
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    MSDS:
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    96T
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    ELISA Kit for Rat SERCA1
    Cat.:
    E15014m
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat SERCA1
    Cat.:
    E15014b
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Rat SERCA1
    Cat.:
    E15014r
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    Packing:
    96T
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    ELISA Kit for Rat SERCA1
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    Please sign in first.
    ELISA Kit for Rat SERCA1
    Cat.:
    E15014c
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat SERCA1
    Cat.:
    U15014c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat SERCA1
    Cat.:
    U15014b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat SERCA1
    Cat.:
    U15014r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat SERCA1
    MSDS:
    Please sign in first.
    CLIA Kit for Rat SERCA1
    Cat.:
    U15014h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat SERCA1
    Cat.:
    U15014m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat SERCA1
    Cat.:
    P15014Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat SERCA1
    Cat.:
    P15014Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat SERCA1
    Polyclonal Antibody for Rat SERCA1
    Polyclonal Antibody for Rat SERCA1
    Polyclonal Antibody for Rat SERCA1
    Cat.:
    P15014Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat SERCA1
    Monoclonal Antibody for Rat SERCA1
    Monoclonal Antibody for Rat SERCA1
    Monoclonal Antibody for Rat SERCA1
    Monoclonal Antibody for Rat SERCA1
    Monoclonal Antibody for Rat SERCA1
    Protein for Rat SERCA1
    Protein for Rat SERCA1
    Protein for Rat SERCA1
    Protein for Rat SERCA1
    Protein for Rat SERCA1
    Protein for Rat SERCA1

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    References
    1. 1.
      "Molecular cloning and quantification of sarcoplasmic reticulum Ca(2+)-ATPase isoforms in rat muscles."
      Wu K.D. , Lytton J.
      Am. J. Physiol.264:C333-C341(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: CD Charles River.
      tissue: Skeletal muscle.
    2. 2.
      "Unloading induces transcriptional activation of the sarco(endo)plasmic reticulum Ca2+-ATPase 1 gene in muscle."
      Peters D.G. , Mitchell-Felton H. , Kandarian S.C.
      Am. J. Physiol.276:C1218-C1225(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 955-994
      strain: Sprague-Dawley.
      tissue: Kidney.
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