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Index > Protein center > Atat1(Gene name) > Mouse
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  • Atat1 (Gene name),
  • Alpha-tubulin N-acetyltransferase (Protein name ),  ATAT_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Atat1(Mec17);
    Protein name:
    Alpha-tubulin N-acetyltransferase(Alpha-TAT;TAT);
    Alternative:
    Acetyltransferase MEC-17;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. May affect microtubule stability and regulate microtubule dynamics. May be involved in neuron development.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    421
    Sequence:
    50:
    MEFPFDVDAL | FPERITVLDQ | HLRPPARRPG | TTTPARVDLQ | QQIMTIVDEL | 
    100:
    GKASAKAQHL | PAPITSALRM | QSNRHVIYIL | KDTSARPAGK | GAIIGFLKVG | 
    150:
    YKKLFVLDDR | EAHNEVEPLC | ILDFYIHESV | QRHGHGRELF | QHMLQKERVE | 
    200:
    PHQLAIDRPS | PKLLKFLNKH | YNLETTVPQV | NNFVIFEGFF | AHQHRPPTSS | 
    250:
    LRATRHSRAA | VADPIPAAPA | RKLPPKRAEG | DIKPYSSSDR | EFLKVAVEPP | 
    300:
    WPLNRAPRRA | TPPAHPPPRS | SSLGNSPDRG | PLRPFVPEQE | LLRSLRLCPP | 
    350:
    HPTARLLLAT | DPGGSPAQRR | RTRGTPWGLV | AQSCHYSRHG | GFNTSFLGTG | 
    400:
    NQERKQGEQE | AEDRSASEDR | VLLLDGSGEE | PTQTGAPRAQ | APPPQSWTVG | 
    421:
    GDIMNARVIR | NLQERRSTRP | W
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    Pfam:
    KEGG:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Alpha-TAT
    ELISA Kit for Mouse Alpha-TAT
    ELISA Kit for Mouse Alpha-TAT
    ELISA Kit for Mouse Alpha-TAT
    ELISA Kit for Mouse Alpha-TAT
    CLIA Kit for Mouse Alpha-TAT
    CLIA Kit for Mouse Alpha-TAT
    CLIA Kit for Mouse Alpha-TAT
    CLIA Kit for Mouse Alpha-TAT
    CLIA Kit for Mouse Alpha-TAT
    Polyclonal Antibody for Mouse Alpha-TAT
    Polyclonal Antibody for Mouse Alpha-TAT
    Polyclonal Antibody for Mouse Alpha-TAT
    Polyclonal Antibody for Mouse Alpha-TAT
    Polyclonal Antibody for Mouse Alpha-TAT
    Monoclonal Antibody for Mouse Alpha-TAT
    Monoclonal Antibody for Mouse Alpha-TAT
    Monoclonal Antibody for Mouse Alpha-TAT
    Monoclonal Antibody for Mouse Alpha-TAT
    Monoclonal Antibody for Mouse Alpha-TAT
    Protein for Mouse Alpha-TAT
    Protein for Mouse Alpha-TAT
    Protein for Mouse Alpha-TAT
    Protein for Mouse Alpha-TAT
    Protein for Mouse Alpha-TAT

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3; 4 AND 5)
      strain: C57BL/6J.
      tissue: Embryo.
      tissue: Embryonic head.
      tissue: Pituitary.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      strain: C57BL/6J.
      strain: Czech II.
      tissue: Mammary gland.
      tissue: Mammary tumor.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    5. 5.
      "Mice lacking alpha-tubulin acetyltransferase 1 are viable but display alpha-tubulin acetylation deficiency and dentate gyrus distortion."
      Kim G.W. , Li L. , Gorbani M. , You L. , Yang X.J.
      J. Biol. Chem.288:20334-20350(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE;DISRUPTION PHENOTYPE
    6. 6.
      "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
      Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-233;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
    7. 7.
      "Tubulin acetyltransferase alphaTAT1 destabilizes microtubules independently of its acetylation activity."
      Kalebic N. , Martinez C. , Perlas E. , Hublitz P. , Bilbao-Cortes D. , Fiedorczuk K. , Andolfo A. , Heppenstall P.A.
      Mol. Cell. Biol.33:1114-1123(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;ACETYLATION AT LYS-56; LYS-146; LYS-233 AND LYS-244;MUTAGENESIS OF LYS-56; GLY-134; GLY-136; LEU-139; LYS-146; LYS-233 AND LYS-244
    8. 8.
      "alphaTAT1 is the major alpha-tubulin acetyltransferase in mice."
      Kalebic N. , Sorrentino S. , Perlas E. , Bolasco G. , Martinez C. , Heppenstall P.A.
      Nat. Commun.4:1962-1962(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH AP2A2
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