Protein name:
Cyclic AMP-dependent transcription factor ATF-2 (cAMP-dependent transcription factor ATF-2) ;
Alternative:
cAMP response element-binding protein CRE-BP1 ;Activating transcription factor 2 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Binds DNA as a dimer and can form a homodimer in the absence of DNA. Can form a heterodimer with JUN. Interacts with SMAD3 and SMAD4. Binds through its N-terminal region to UTF1 which acts as a coactivator of ATF2 transcriptional activity.
Function:
Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2/JUN complex.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MSDDKPFLCT | APGCGQRFTN | EDHLAVHKHK | HEMTLKFGPA | RNDSVIVADQ |
100:
TPTPTRFLKN | CEEVGLFNEL | ASPFENEFKK | ASEDDIKKMP | LDLSPLATPI |
150:
IRSKIEEPSV | VETTHQDSPL | PHPESTTNDE | KEIPLAQTAQ | PTSAIVRPAS |
200:
LQVPNVLLTS | SDSSVIIQQA | VPSPTSSTVI | TQAPSSNRPI | VPVPGPFPLL |
250:
LHLPNGQTMP | VAIPASITSS | NVHVPAAVPL | VRPVTMVPSV | PGIPGPSSPQ |
300:
PVQSEAKMRL | KAALTQQHPP | VTNGDTVKGH | GSGLVRAQSE | ESRPQSLQQP |
350:
ATSTTETPAS | PAHTTPQTQN | TSGRRRRAAN | EDPDEKRRKF | LERNRAAASR |
400:
CRQKRKVWVQ | SLEKKAEDLS | SLNGQLQSEV | TLLRNEVAQL | KQLLLAHKDC |
450:
PVTAMQKKSG | YHTADKDDSS | EDLSVPSSPH | TEAIQHSSVS | TSNGVSSTSK |
487:
TEAGATSVLT | QMADQSTEPA | LSQIVMAPSS | QAQPSGS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Chicken
Human
Mouse
ELISA Kit for Rat cAMP-dependent transcription factor ATF-2
ELISA Kit for Rat cAMP-dependent transcription factor ATF-2
ELISA Kit for Rat cAMP-dependent transcription factor ATF-2
ELISA Kit for Rat cAMP-dependent transcription factor ATF-2
CLIA Kit for Rat cAMP-dependent transcription factor ATF-2
CLIA Kit for Rat cAMP-dependent transcription factor ATF-2
CLIA Kit for Rat cAMP-dependent transcription factor ATF-2
CLIA Kit for Rat cAMP-dependent transcription factor ATF-2
Polyclonal Antibody for Rat cAMP-dependent transcription factor ATF-2
Polyclonal Antibody for Rat cAMP-dependent transcription factor ATF-2
Polyclonal Antibody for Rat cAMP-dependent transcription factor ATF-2
Polyclonal Antibody for Rat cAMP-dependent transcription factor ATF-2
Monoclonal Antibody for Rat cAMP-dependent transcription factor ATF-2
Monoclonal Antibody for Rat cAMP-dependent transcription factor ATF-2
Monoclonal Antibody for Rat cAMP-dependent transcription factor ATF-2
Monoclonal Antibody for Rat cAMP-dependent transcription factor ATF-2
Protein for Rat cAMP-dependent transcription factor ATF-2
Protein for Rat cAMP-dependent transcription factor ATF-2
Protein for Rat cAMP-dependent transcription factor ATF-2
Protein for Rat cAMP-dependent transcription factor ATF-2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
tissue :
Brain .
2.
Muramatsu S.
Submitted (1995-10) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
strain :
Sprague-Dawley .
tissue :
Brain .