Protein name:
Cyclic AMP-dependent transcription factor ATF-4 (cAMP-dependent transcription factor ATF-4) ;
Alternative:
Activating transcription factor 4 (rATF-4) ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Interaction with SATB2 results in enhanced DNA binding and transactivation by these transcription factors (By similarity). Binds DNA as a homo- or heterodimer. Interacts with the N-terminal region of CEP290 (By similarity). Interacts with the C-terminal region of GABBR1 via the leucine zipper of its C-terminal bZIP domain. Interacts with the C-terminal region of GABBR2. Forms a heterodimer with TXLNG in osteoblasts (By similarity). Interacts with NEK6.
Function:
Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters.
Subcellular Location:
Cytoplasm
Cell membrane
Nucleus
Cytoplasm
cytoskeleton
centrosome
Colocalizes with GABBR1 in hippocampal neuron dendritic membranes. Co-localizes with NEK6 in the centrosome.
Protein Attributes:
50:
MTEMSFLNSE | VLAGDLMSPF | DQSGLGAEES | LGLLDDYLEV | AKHFKPHGFS |
100:
SDKAGSSEWL | AMDGLVSASD | TGKEDAFSGT | DWMLEKMDLK | EFDFDALFRM |
150:
DDLETMPDEL | LATLDDTCDL | FAPLVQETNK | EPPQTVNPIG | HLPESVIKVD |
200:
QAAPFTFLQP | LPCSPGFLSS | TPDHSFSLEL | GSEVDISEGD | RKPDSAAYIT |
250:
LTPQCVKEED | TPSDSDSGIC | MSPESYLGSP | QHSPSTSRAP | PDSLPSPGVP |
300:
RGSRPKPYDP | PGVSVTAKVK | TEKLDKKLKK | MEQNKTAATR | YRQKKRAEQE |
347:
ALTGECKELE | KKNEALKEKA | DSLAKEIQYL | KDLIEEVRKA | RGKKRVP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Bovine
Human
Rat
ELISA Kit for Rat cAMP-dependent transcription factor ATF-4
ELISA Kit for Rat cAMP-dependent transcription factor ATF-4
ELISA Kit for Rat cAMP-dependent transcription factor ATF-4
ELISA Kit for Rat cAMP-dependent transcription factor ATF-4
CLIA Kit for Rat cAMP-dependent transcription factor ATF-4
CLIA Kit for Rat cAMP-dependent transcription factor ATF-4
CLIA Kit for Rat cAMP-dependent transcription factor ATF-4
CLIA Kit for Rat cAMP-dependent transcription factor ATF-4
Polyclonal Antibody for Rat cAMP-dependent transcription factor ATF-4
Polyclonal Antibody for Rat cAMP-dependent transcription factor ATF-4
Polyclonal Antibody for Rat cAMP-dependent transcription factor ATF-4
Polyclonal Antibody for Rat cAMP-dependent transcription factor ATF-4
Monoclonal Antibody for Rat cAMP-dependent transcription factor ATF-4
Monoclonal Antibody for Rat cAMP-dependent transcription factor ATF-4
Monoclonal Antibody for Rat cAMP-dependent transcription factor ATF-4
Monoclonal Antibody for Rat cAMP-dependent transcription factor ATF-4
Protein for Rat cAMP-dependent transcription factor ATF-4
Protein for Rat cAMP-dependent transcription factor ATF-4
Protein for Rat cAMP-dependent transcription factor ATF-4
Protein for Rat cAMP-dependent transcription factor ATF-4
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;INTERACTION WITH GABBR1 AND GABBR2;SUBCELLULAR LOCATION
tissue :
Brain .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY