Gene name:
    ATF6B (CREBL1;G13) ;
    
 
    Protein name:
    Cyclic AMP-dependent transcription factor ATF-6 beta (cAMP-dependent transcription factor ATF-6 beta) ;
    
    Alternative:
    
    Protein G13 ;Activating transcription factor 6 beta (ATF6-beta) ;cAMP-responsive element-binding protein-like 1 ;cAMP response element-binding protein-related protein (Creb-rp) ;
    
    
 
    Organism:
        
        
        
        
        
        
    
        Human  (Homo sapiens).  
    
 
General Annotation
    Sub Unit:
    Homodimer and heterodimer with ATF6-alpha. The dimer interacts with the nuclear transcription factor Y (NF-Y) trimer through direct binding to NF-Y subunit C (NF-YC).
    
 
    Function:
    Transcriptional factor that acts in the unfolded protein response (UPR) pathway by activating UPR target genes induced during ER stress. Binds DNA on the 5'-CCAC[GA]-3' half of the ER stress response element (ERSE) (5'-CCAATN(9)CCAC[GA]-3') when NF-Y is bound to ERSE.
    
 
    
        
        Subcellular Location:
        
    
     
    Processed cyclic AMP-dependent transcription factor ATF-6 beta  
     
      Nucleus 
      
    Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus. 
  
    
 
    
    Protein Attributes:
    
    50:
    MAELMLLSEI |  ADPTRFFTDN |  LLSPEDWGLQ |  NSTLYSGLDE |  VAEEQTQLFR |  
    
 
    100:
    CPEQDVPFDG |  SSLDVGMDVS |  PSEPPWELLP |  IFPDLQVKSE |  PSSPCSSSSL |  
    
 
    150:
    SSESSRLSTE |  PSSEALGVGE |  VLHVKTESLA |  PPLCLLGDDP |  TSSFETVQIN |  
    
 
    200:
    VIPTSDDSSD |  VQTKIEPVSP |  CSSVNSEASL |  LSADSSSQAF |  IGEEVLEVKT |  
    
 
    250:
    ESLSPSGCLL |  WDVPAPSLGA |  VQISMGPSLD |  GSSGKALPTR |  KPPLQPKPVV |  
    
 
    300:
    LTTVPMPSRA |  VPPSTTVLLQ |  SLVQPPPVSP |  VVLIQGAIRV |  QPEGPAPSLP |  
    
 
    350:
    RPERKSIVPA |  PMPGNSCPPE |  VDAKLLKRQQ |  RMIKNRESAC |  QSRRKKKEYL |  
    
 
    400:
    QGLEARLQAV |  LADNQQLRRE |  NAALRRRLEA |  LLAENSELKL |  GSGNRKVVCI |  
    
 
    450:
    MVFLLFIAFN |  FGPVSISEPP |  SAPISPRMNK |  GEPQPRRHLL |  GFSEQEPVQG |  
    
 
    500:
    VEPLQGSSQG |  PKEPQPSPTD |  QPSFSNLTAF |  PGGAKELLLR |  DLDQLFLSSD |  
    
 
    550:
    CRHFNRTESL |  RLADELSGWV |  QRHQRGRRKI |  PQRAQERQKS |  QPRKKSPPVK |  
    
 
    600:
    AVPIQPPGPP |  ERDSVGQLQL |  YRHPDRSQPA |  FLDAIDRRED |  TFYVVSFRRD |  
    
 
    650:
    HLLLPAISHN |  KTSRPKMSLV |  MPAMAPNETL |  SGRGAPGDYE |  EMMQIECEVM |  
    
 
    700:
    DTRVIHIKTS |  TVPPSLRKQP |  SPTPGNATGG |  PLPVSAASQA |  HQASHQPLYL |  
    
 
      Vaild Sequence:
    
 
Related Databases
Uniprot:
 
 
    
        
        ELISA Kit
         
        
        CLIA Kit
         
        
        Polyclonal Antibody
         
        
        Monoclonal Antibody
         
        
        Protein
         
        
     
FOR
    
        
        Mouse
         
        
        Human
         
        
     
    
        ELISA Kit for Human cAMP-dependent transcription factor ATF-6 beta
        
     
    
    
    
    
    
    
 
    
        ELISA Kit for Human cAMP-dependent transcription factor ATF-6 beta
        
     
    
    
    
    
    
    
 
    
        CLIA Kit for Human cAMP-dependent transcription factor ATF-6 beta
        
     
    
    
    
    
    
    
 
    
        CLIA Kit for Human cAMP-dependent transcription factor ATF-6 beta
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human cAMP-dependent transcription factor ATF-6 beta
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human cAMP-dependent transcription factor ATF-6 beta
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human cAMP-dependent transcription factor ATF-6 beta
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human cAMP-dependent transcription factor ATF-6 beta
        
     
    
    
    
    
    
    
 
    
        Protein for Human cAMP-dependent transcription factor ATF-6 beta
        
     
    
    
    
    
    
    
 
    
        Protein for Human cAMP-dependent transcription factor ATF-6 beta
        
     
    
    
    
    
    
    
 
 
 
 
 
 
 
 
    R&D Technical Data
    
    
    
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        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
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    Precision
    
    
    
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        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
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        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
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    Recovery
    
    
    
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        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
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    Linearity
    
    
    
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        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
 
    
    
    References
    
    
        
            
        
            
                1.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1) 
                    
                    
                    tissue :
                    
Tonsil .  
             
         
            
        
            
                2.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 2) 
                    
                    
                 
             
         
            
        
            
                3.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] 
                    
                    
                 
             
         
            
        
            
                4.
                
                    
                        
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                        [
PubMed ]
                        [
Europe PMC ]
                        [
Abstract ]
                        
                    
 
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] 
                    
                    
                 
             
         
            
        
            
                5.
                
                    
                        
                        
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                              more...   
                             
                        
                        
                            Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
                        
                        
                    
 
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] 
                    
                    
                 
             
         
            
        
            
                6.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for PARTIAL NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2) 
                    
                    
                 
             
         
            
        
            
                7.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for CHARACTERIZATION 
                    
                    
                 
             
         
            
        
            
                8.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS] 
                    
                    
                 
             
         
            
        
            
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Lasa M. 
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Polevoda B. 
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Gazquez C. 
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                            Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012)
                         
                        
                        
                        [
PubMed ]
                        [
Europe PMC ]
                        [
Abstract ]
                        
                    
 
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]