Protein name:
Ubiquitin-like-conjugating enzyme ATG3 ;
Alternative:
Autophagy-related protein 3 (APG3-like) ;
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Interacts with ATG7 and ATG12. The complex, composed of ATG3 and ATG7, plays a role in the conjugation of ATG12 to ATG5.
Function:
E2-like enzyme involved in autophagy and mitochondrial homeostasis. Catalyzes the conjugation of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A) to phosphatidylethanolamine (PE). PE-conjugation to ATG8-like proteins is essential for autophagy. Preferred substrate is MAP1LC3A. Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MQNVINTVKG | KALEVAEYLT | PVLKESKFKE | TGVITPEEFV | AAGDHLVHHC |
100:
PTWQWATGEE | LKVKAYLPSG | KQFLVTKNVP | CYKRCKQMEY | SDELEAIIEE |
150:
DDGDGGWVDT | YHNTGIAGIT | EAVKEITLES | KDSIKLQDCS | ALCEEEEEED |
200:
EGEAADMEEY | EESGLLETDE | ATLDTRKIVE | ACKAKTDAGG | EDAILQTRTY |
250:
DLYITYDKYY | QTPRLWLFGY | DEQRQPLTVE | HMYEDISQDH | VKKTVTIENH |
300:
PHLPPPPMCS | VHPCRHAEVM | KKIIETVAEG | GGELGVHMYL | LIFLKFVQAV |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Mouse
Human
Bovine
ELISA Kit for Bovine Ubiquitin-like-conjugating enzyme ATG3
ELISA Kit for Bovine Ubiquitin-like-conjugating enzyme ATG3
ELISA Kit for Bovine Ubiquitin-like-conjugating enzyme ATG3
ELISA Kit for Bovine Ubiquitin-like-conjugating enzyme ATG3
CLIA Kit for Bovine Ubiquitin-like-conjugating enzyme ATG3
CLIA Kit for Bovine Ubiquitin-like-conjugating enzyme ATG3
CLIA Kit for Bovine Ubiquitin-like-conjugating enzyme ATG3
CLIA Kit for Bovine Ubiquitin-like-conjugating enzyme ATG3
Polyclonal Antibody for Bovine Ubiquitin-like-conjugating enzyme ATG3
Polyclonal Antibody for Bovine Ubiquitin-like-conjugating enzyme ATG3
Polyclonal Antibody for Bovine Ubiquitin-like-conjugating enzyme ATG3
Polyclonal Antibody for Bovine Ubiquitin-like-conjugating enzyme ATG3
Monoclonal Antibody for Bovine Ubiquitin-like-conjugating enzyme ATG3
Monoclonal Antibody for Bovine Ubiquitin-like-conjugating enzyme ATG3
Monoclonal Antibody for Bovine Ubiquitin-like-conjugating enzyme ATG3
Monoclonal Antibody for Bovine Ubiquitin-like-conjugating enzyme ATG3
Protein for Bovine Ubiquitin-like-conjugating enzyme ATG3
Protein for Bovine Ubiquitin-like-conjugating enzyme ATG3
Protein for Bovine Ubiquitin-like-conjugating enzyme ATG3
Protein for Bovine Ubiquitin-like-conjugating enzyme ATG3
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Hereford .
tissue :
Fetal pons .