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Index > Protein center > Atp5b(Gene name) > Rat
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  • Atp5b (Gene name),
  • ATP synthase subunit beta, mitochondrial (Protein name ),  ATPB_RAT from NCBI database.
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  • General Annotation
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  • Gene name:
    Atp5b;
    Protein name:
    ATP synthase subunit beta, mitochondrial;
    Alternative:

    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
    Function:
    Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
    Subcellular Location:
    Mitochondrion Mitochondrion inner membrane Peripheral membrane protein.
    Protein Attributes:
    Sequence length:
    529
    Sequence:
    50:
    MLSLVGRVAS | ASASGALRGL | NPLAALPQAH | LLLRTAPAGV | HPARDYAAQS | 
    100:
    SAAPKAGTAT | GQIVAVIGAV | VDVQFDEGLP | PILNALEVQG | RESRLVLEVA | 
    150:
    QHLGESTVRT | IAMDGTEGLV | RGQKVLDSGA | PIKIPVGPET | LGRIMNVIGE | 
    200:
    PIDERGPIKT | KQFAPIHAEA | PEFIEMSVEQ | EILVTGIKVV | DLLAPYAKGG | 
    250:
    KIGLFGGAGV | GKTVLIMELI | NNVAKAHGGY | SVFAGVGERT | REGNDLYHEM | 
    300:
    IESGVINLKD | ATSKVALVYG | QMNEPPGARA | RVALTGLTVA | EYFRDQEGQD | 
    350:
    VLLFIDNIFR | FTQAGSEVSA | LLGRIPSAVG | YQPTLATDMG | TMQERITTTK | 
    400:
    KGSITSVQAI | YVPADDLTDP | APATTFAHLD | ATTVLSRAIA | ELGIYPAVDP | 
    450:
    LDSTSRIMDP | NIVGSEHYDV | ARGVQKILQD | YKSLQDIIAI | LGMDELSEED | 
    500:
    KLTVSRARKI | QRFLSQPFQV | AEVFTGHMGK | LVPLKETIKG | FQQILAGDYD | 
    529:
    HLPEQAFYMV | GPIEEAVAKA | DKLAEEHGS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Rat ATP synthase subunit beta, mitochondrial
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    ELISA Kit for Rat ATP synthase subunit beta, mitochondrial
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    ELISA Kit for Rat ATP synthase subunit beta, mitochondrial
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    ELISA Kit for Rat ATP synthase subunit beta, mitochondrial
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    ELISA Kit for Rat ATP synthase subunit beta, mitochondrial
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    ELISA Kit for Rat ATP synthase subunit beta, mitochondrial
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    CLIA Kit for Rat ATP synthase subunit beta, mitochondrial
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    U12585m
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    CLIA Kit for Rat ATP synthase subunit beta, mitochondrial
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    U12585c
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    CLIA Kit for Rat ATP synthase subunit beta, mitochondrial
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    U12585b
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    96T
    CLIA Kit for Rat ATP synthase subunit beta, mitochondrial
    Cat.:
    U12585d
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    96T
    CLIA Kit for Rat ATP synthase subunit beta, mitochondrial
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    U12585h
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    CLIA Kit for Rat ATP synthase subunit beta, mitochondrial
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    U12585r
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    Polyclonal Antibody for Rat ATP synthase subunit beta, mitochondrial
    Polyclonal Antibody for Rat ATP synthase subunit beta, mitochondrial
    Polyclonal Antibody for Rat ATP synthase subunit beta, mitochondrial
    Polyclonal Antibody for Rat ATP synthase subunit beta, mitochondrial
    Cat.:
    P12585Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat ATP synthase subunit beta, mitochondrial
    Cat.:
    P12585Rb-r
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    40ug/0.2ml
    Polyclonal Antibody for Rat ATP synthase subunit beta, mitochondrial
    Cat.:
    P12585Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat ATP synthase subunit beta, mitochondrial
    Monoclonal Antibody for Rat ATP synthase subunit beta, mitochondrial
    Monoclonal Antibody for Rat ATP synthase subunit beta, mitochondrial
    Monoclonal Antibody for Rat ATP synthase subunit beta, mitochondrial
    Monoclonal Antibody for Rat ATP synthase subunit beta, mitochondrial
    Monoclonal Antibody for Rat ATP synthase subunit beta, mitochondrial
    Protein for Rat ATP synthase subunit beta, mitochondrial
    Protein for Rat ATP synthase subunit beta, mitochondrial
    Protein for Rat ATP synthase subunit beta, mitochondrial
    Protein for Rat ATP synthase subunit beta, mitochondrial
    Protein for Rat ATP synthase subunit beta, mitochondrial
    Protein for Rat ATP synthase subunit beta, mitochondrial

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    References
    1. 1.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Prostate.
    2. 2.
      "Studies on the biogenesis of the mammalian ATP synthase complex: isolation and characterization of a full-length cDNA encoding the rat F1-beta-subunit."
      Boulet D. , Poirier J. , Cote C.
      Biochem. Biophys. Res. Commun.159:1184-1190(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-60
    3. 3.
      "N-terminal sequence of the rat liver beta-subunit in the mitochondrial ATPase-ATPsynthase."
      Cretin F. , Baggetto L.G. , Denoroy L. , Godinot C.
      Biochem. Biophys. Res. Commun.164:1165-1169(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 47-60
      tissue: Liver.
    4. 4.
      "Beta subunit of rat liver mitochondrial ATP synthase: cDNA cloning, amino acid sequence, expression in Escherichia coli, and structural relationship to adenylate kinase."
      Garboczi D.N. , Fox A.H. , Gerring S.L. , Pedersen P.L.
      Biochemistry27:553-560(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 58-529
    5. 5.
      "Mitochondrial ATP synthase F1-beta-subunit is a calcium-binding protein."
      Hubbard M.J. , McHugh N.J.
      FEBS Lett.391:323-329(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 87-98; 208-219; 225-234; 268-279 AND 433-454;CALCIUM-BINDING
    6. 6.
      Lubec G. , Afjehi-Sadat L. , Chen W.-Q. , Kang S.U.
      Submitted (2007-07) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 95-121; 125-155; 189-198; 202-239; 226-239; 242-259; 265-279; 282-345; 388-422; 427-456 AND 463-480;IDENTIFICATION BY MASS SPECTROMETRY
      strain: Sprague-Dawley.
      tissue: Brain.
      tissue: Hippocampus.
      tissue: Spinal cord.
    7. 7.
      "Molecular cloning of cDNA for the rat F1-ATPase beta subunit."
      Lee Y.M. , Chu L.P. , Lee S.C.
      Taiwan Yi Xue Hui Za Zhi87:933-938(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 172-529
    8. 8.
      "Mass spectrometry and tandem mass spectrometry analysis of rat mitochondrial ATP synthase: up-regulation in pancreatic acinar cells treated with cerulein."
      Yu J.-H. , Yun S.-Y. , Lim J.-W. , Kim H. , Kim K.-H.
      Proteomics3:2437-2445(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Pancreatic acinar cell.
    9. 9.
      "Identification of two proteins associated with mammalian ATP synthase."
      Meyer B. , Wittig I. , Trifilieff E. , Karas M. , Schaegger H.
      Mol. Cell. Proteomics6:1690-1699(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;IDENTIFICATION IN THE ATP SYNTHASE COMPLEX
    10. 10.
      "Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase."
      Alavian K.N. , Li H. , Collis L. , Bonanni L. , Zeng L. , Sacchetti S. , Lazrove E. , Nabili P. , Flaherty B. , Graham M. , Chen Y. , Messerli S.M. , Mariggio M.A. , Rahner C. , McNay E. , Shore G.C. , Smith P.J. , Hardwick J.M. , more...
      Nat. Cell Biol.13:1224-1233(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH BCL2L1
    11. 11.
      "Discovery and confirmation of O-GlcNAcylated proteins in rat liver mitochondria by combination of mass spectrometry and immunological methods."
      Cao W. , Cao J. , Huang J. , Yao J. , Yan G. , Xu H. , Yang P.
      PLoS ONE8:E76399-E76399(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT SER-106
    12. 12.
      "The 2.8-A structure of rat liver F1-ATPase: configuration of a critical intermediate in ATP synthesis/hydrolysis."
      Bianchet M.A. , Hullihen J. , Pedersen P.L. , Amzel L.M.
      Proc. Natl. Acad. Sci. U.S.A.95:11065-11070(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS)
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