Protein name:
Attractin ;
Alternative:
Protein zitter ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Monomer and homotrimer.
Function:
Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines (By similarity). May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti (By similarity). Has a critical role in normal myelination in the central nervous system.
Subcellular Location:
Isoform 2
Secreted
Protein Attributes:
50:
MVAAAAAAEA | TEARLRGYTT | ATAAPAGWKE | RQHRPCAATG | AWRPWPRAGL |
100:
CLPRVLSRAL | SPPPLLPLLP | LLFSLLLLPL | PREAEAAAVA | AAVSGSAAAE |
150:
AKECDRPCVN | GGRCNPGTGQ | CVCPTGWVGE | QCQHCGGRFR | LTGSSGFVTD |
200:
GPGNYKYKTK | CTWLIEGQPN | KIMRLRFNHF | ATECSWDHLY | VYDGDSIYAP |
250:
LIAAFSGLIV | PERDGNETAP | EVTVTSGYAL | LHFFSDAAYN | LTGFNITYNF |
300:
DMCPNNCSGR | GECKSSNSSS | TVECECSENW | KGESCDIPHC | TDNCGFPHRG |
350:
ICNASDTRGC | SCFPHWQGPG | CSIPVPANQS | FWTREEYSDL | KLPRASHKAV |
400:
VNGNIMWVVG | GYMFNHSDYS | MVLAYDLASR | EWLSLNHSVN | SVVVRYGHSL |
450:
ALHKDKIYMY | GGKIDSTGNV | TNELRVFHIH | NESWVLLTPK | AKDQYAVVGH |
500:
SAHIVTLSSG | RVVMLVIFGH | CPLYGYISVV | QEYDLEKNTW | SILQTQGALV |
550:
QGGYGHSSVY | DHRTKALYVH | GGYKAFSANK | YRLADDLYRY | HVDTQMWTIL |
600:
KDSRFFRYLH | TAVIVSGTML | VFGGNTHNDT | SMSHGAKCFS | SDFMAYDIAC |
650:
DRWSVLPRPE | LHHDVNRFGH | SAVLHNSTMY | VFGGFNSLLL | SDVLVFTSEQ |
700:
CDAHRSEAAC | VAAGPGIRCL | WDTQSSRCTS | WELATEEQAE | KLKSECFSKR |
750:
TLDHDRCDQH | TDCYSCTANT | NDCHWCNDHC | VPVNHSCTEG | QISIAKYDNC |
800:
PKDNPMYYCN | KKTSCRSCAL | DQNCQWEPRN | QECIALPENI | CGIGWHLVGN |
850:
SCLKITTAKE | NYDNAKLSCR | NHNAFLASLT | SQKKVEFVLK | QLRLMQSSQS |
900:
TSKLTLTPWV | GLRKINVSYW | CWEDMSPFTN | SLLQWMPSEP | SDAGFCGILS |
950:
EPSTRGLKAA | TCINPLNGSV | CERPANHSAK | QCRTPCALRT | ACGECTSSSS |
1000:
ECMWCSNMKQ | CVDSNAYVAS | FPFGQCMEWY | TMSSCPPENC | SGYCTCSHCL |
1050:
EQPGCGWCTD | PSNTGKGKCI | EGSYKGPVKM | PSHASTGNVY | PQPLLNSSMC |
1100:
LEDSRYNWSF | IHCPACQCNG | HSKCINQSIC | EKCEDLTTGK | HCETCISGFY |
1150:
GDPTNGGKCQ | PCKCNGHASL | CNTNTGKCFC | TTKGVKGEEC | QLCEVENRYQ |
1200:
GNPLKGTCYY | TLLIDYQFTF | SLSQEDDRYY | TAINFVATPD | EQNRDLDMFI |
1250:
NASKNFNLNI | TWATSFPAGT | QTGEEVPVVS | KTNIKEYKDS | FSNEKFDFRN |
1300:
HPNITFFVYV | SNFTWPIKIQ | IAFSQHSNFM | DLVQFFVTFF | SCFLSLLLVA |
1350:
AVVWKIKQSC | WASRRREQLL | REMQQMASRP | FASVNVALET | DEEPPDLIGG |
1400:
SIKTVPKPIA | LEPCFGNKAA | VLSVFVRLPR | GLGGIPPPGQ | SGLAVASALV |
1432:
DISQQMPIVY | KEKSGAVRNR | KQQPPAQPGT | CI
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
ELISA Kit for Rat Attractin
ELISA Kit for Rat Attractin
ELISA Kit for Rat Attractin
CLIA Kit for Rat Attractin
CLIA Kit for Rat Attractin
CLIA Kit for Rat Attractin
Polyclonal Antibody for Rat Attractin
Polyclonal Antibody for Rat Attractin
Polyclonal Antibody for Rat Attractin
Monoclonal Antibody for Rat Attractin
Monoclonal Antibody for Rat Attractin
Monoclonal Antibody for Rat Attractin
Protein for Rat Attractin
Protein for Rat Attractin
Protein for Rat Attractin
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Attractin/mahogany/zitter plays a critical role in myelination of the central nervous system."
Kuramoto T.
,
Kitada K.
,
Inui T.
,
Sasaki Y.
,
Ito K.
,
Hase T.
,
Kawaguchi S.
,
Ogawa Y.
,
Nakao K.
,
Barsh G.S.
,
Nagao M.
,
Ushijima T.
,
Serikawa T.
Proc. Natl. Acad. Sci. U.S.A.98:559-564(2001)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1);NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION;DISEASE
strain :
WTC .
tissue :
Brain .