Protein name:
Advillin ;
Alternative:
p92 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Associates (via C-terminus) with actin. Interacts with SCARF1 (By similarity). Interacts with F-actin.
Function:
Ca(2+)-regulated actin-binding protein. May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1-mediated regulation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast. Plays a role in ciliogenesis.
Subcellular Location:
Cytoplasm
cytoskeleton
Cell projection
Cell projection
axon
Protein Attributes:
50:
MPLTSAFRAV | DNDPGIIVWR | IEKMELALVP | VSAHGNFYEG | DCYVILSTRR |
100:
VASLLSQDIH | FWIGKDSSQD | EQSCAAIYTT | QLDDYLGGSP | VQHREVQYHE |
150:
SDTFRGYFKQ | GIIYKQGGVA | SGMKHVETNT | YDVKRLLHVK | GKRNIRATEV |
200:
EMSWDSFNRG | DVFLLDLGKV | IIQWNGPESN | SGERLKAMLL | AKDIRDRERG |
250:
GRAKIGVIEG | DKEAASPELM | KVLQDTLGRR | SIIKPTVPDE | IIDQKQKSTI |
300:
MLYHISDSAG | QLAVTEVATR | PLVQDLLNHD | DCYILDQSGT | KIYVWKGKGA |
350:
TKAEKQAAMS | KALGFIKMKS | YPSSTNVETV | NDGAESAMFK | QLFQKWSVKD |
400:
QTMGLGKTFS | IGKIAKVFQD | KFDVTLLHTK | PEVAAQERMV | DDGNGKVEVW |
450:
RIENLELVPV | EYQWYGFFYG | GDCYLVLYTY | EVNGKPHHIL | YIWQGRHASQ |
500:
DELAASAYQA | VEVDRQFDGA | AVQVRVRMGT | EPRHFMAIFK | GKLVIFEGGT |
550:
SRKGNAEPDP | PVRLFQIHGN | DKSNTKAVEV | PAFASSLNSN | DVFLLRTQAE |
600:
HYLWYGKGSS | GDERAMAKEL | ASLLCDGSEN | TVAEGQEPAE | FWDLLGGKTP |
650:
YANDKRLQQE | ILDVQSRLFE | CSNKTGQFVV | TEITDFTQDD | LNPTDVMLLD |
700:
TWDQVFLWIG | AEANATEKES | ALATAQQYLH | THPSGRDPDT | PILIIKQGFE |
750:
PPIFTGWFLA | WDPNIWSAGK | TYEQLKEELG | DAAAIMRITA | DMKNATLSLN |
800:
SNDSEPKYYP | IAVLLKNQNQ | ELPEDVNPAK | KENYLSEQDF | VSVFGITRGQ |
819:
FAALPGWKQL | QMKKEKGLF
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Human Advillin
ELISA Kit for Human Advillin
ELISA Kit for Human Advillin
CLIA Kit for Human Advillin
CLIA Kit for Human Advillin
CLIA Kit for Human Advillin
Polyclonal Antibody for Human Advillin
Polyclonal Antibody for Human Advillin
Polyclonal Antibody for Human Advillin
Monoclonal Antibody for Human Advillin
Monoclonal Antibody for Human Advillin
Monoclonal Antibody for Human Advillin
Protein for Human Advillin
Protein for Human Advillin
Protein for Human Advillin
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT GLU-204
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT GLU-204
tissue :
Brain .
3.
"The finished DNA sequence of human chromosome 12."
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT GLU-204
4.
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more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANT GLU-204
6.
"Genomic structure, chromosome mapping and expression analysis of the human AVIL gene, and its exclusion as a candidate for locus for inflammatory bowel disease at 12q13-14 (IBD2)."
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Croucher P.J.
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Gene288:179-185(2002)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY NMR OF 784-819;INTERACTION WITH F-ACTIN;MUTAGENESIS OF TRP-62