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Index > Protein center > BCL11B(Gene name) > Human
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  • BCL11B (Gene name),
  • B-cell lymphoma/leukemia 11B (Protein name ),  BC11B_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    BCL11B(CTIP2;RIT1);
    Protein name:
    B-cell lymphoma/leukemia 11B(BCL-11B);
    Alternative:
    COUP-TF-interacting protein 2;B-cell CLL/lymphoma 11B;Radiation-induced tumor suppressor gene 1 protein(hRit1);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with TFCOUP1, SIRT1, ARP1 and EAR2.
    Function:
    Tumor-suppressor protein involved in T-cell lymphomas. May function on the P53-signaling pathway. May be a key regulator of both differentiation and survival during thymocyte development. Repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    894
    Sequence:
    50:
    MSRRKQGNPQ | HLSQRELITP | EADHVEAAIL | EEDEGLEIEE | PSGLGLMVGG | 
    100:
    PDPDLLTCGQ | CQMNFPLGDI | LVFIEHKRKQ | CGGSLGACYD | KALDKDSPPP | 
    150:
    SSRSELRKVS | EPVEIGIQVT | PDEDDHLLSP | TKGICPKQEN | IAGPCRPAQL | 
    200:
    PAVAPIAASS | HPHSSVITSP | LRALGALPPC | LPLPCCSARP | VSGDGTQGEG | 
    250:
    QTEAPFGCQC | QLSGKDEPSS | YICTTCKQPF | NSAWFLLQHA | QNTHGFRIYL | 
    300:
    EPGPASSSLT | PRLTIPPPLG | PEAVAQSPLM | NFLGDSNPFN | LLRMTGPILR | 
    350:
    DHPGFGEGRL | PGTPPLFSPP | PRHHLDPHRL | SAEEMGLVAQ | HPSAFDRVMR | 
    400:
    LNPMAIDSPA | MDFSRRLREL | AGNSSTPPPV | SPGRGNPMHR | LLNPFQPSPK | 
    450:
    SPFLSTPPLP | PMPPGGTPPP | QPPAKSKSCE | FCGKTFKFQS | NLIVHRRSHT | 
    500:
    GEKPYKCQLC | DHACSQASKL | KRHMKTHMHK | AGSLAGRSDD | GLSAASSPEP | 
    550:
    GTSELAGEGL | KAADGDFRHH | ESDPSLGHEP | EEEDEEEEEE | EEELLLENES | 
    600:
    RPESSFSMDS | ELSRNRENGG | GGVPGVPGAG | GGAAKALADE | KALVLGKVME | 
    650:
    NVGLGALPQY | GELLADKQKR | GAFLKRAAGG | GDAGDDDDAG | GCGDAGAGGA | 
    700:
    VNGRGGGFAP | GTEPFPGLFP | RKPAPLPSPG | LNSAAKRIKV | EKDLELPPAA | 
    750:
    LIPSENVYSQ | WLVGYAASRH | FMKDPFLGFT | DARQSPFATS | SEHSSENGSL | 
    800:
    RFSTPPGDLL | DGGLSGRSGT | ASGGSTPHLG | GPGPGRPSSK | EGRRSDTCEY | 
    850:
    CGKVFKNCSN | LTVHRRSHTG | ERPYKCELCN | YACAQSSKLT | RHMKTHGQIG | 
    894:
    KEVYRCDICQ | MPFSVYSTLE | KHMKKWHGEH | LLTNDVKIEQ | AERS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    MIM:
    Pfam:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human BCL-11B
    Cat.:
    E14966h
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human BCL-11B
    Cat.:
    E14966m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human BCL-11B
    Cat.:
    U14966m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human BCL-11B
    Cat.:
    U14966h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human BCL-11B
    Polyclonal Antibody for Human BCL-11B
    Monoclonal Antibody for Human BCL-11B
    Monoclonal Antibody for Human BCL-11B
    Protein for Human BCL-11B
    Protein for Human BCL-11B

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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
    2. 2.
      "Homozygous deletions and point mutations of the Rit1/Bcl11b gene in gamma-ray induced mouse thymic lymphomas."
      Wakabayashi Y. , Inoue J. , Takahashi Y. , Matsuki A. , Kosugi-Okano H. , Shinbo T. , Mishima Y. , Niwa O. , Kominami R.
      Biochem. Biophys. Res. Commun.301:598-603(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Thymus.
    3. 3.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-97; THR-120; SER-256; THR-260; SER-277; SER-358; THR-376; SER-381; SER-398; THR-417; SER-483; SER-488; SER-496; SER-497; SER-678 AND SER-765;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    4. 4.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-851;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] PRO-331
    6. 6.
      "Resequencing of 29 candidate genes in patients with familial and sporadic amyotrophic lateral sclerosis."
      Daoud H. , Valdmanis P.N. , Gros-Louis F. , Belzil V. , Spiegelman D. , Henrion E. , Diallo O. , Desjarlais A. , Gauthier J. , Camu W. , Dion P.A. , Rouleau G.A.
      Arch. Neurol.68:587-593(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS VAL-32 AND SER-229
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