BCL3 ELISA Kit for Human(Homo sapiens) | EIAab.comBCL3 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > BCL3(Gene name) > Human

BCL3 (Gene name),

B-cell lymphoma 3 protein (Protein name ), BCL3_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

BCL3(BCL4;D19S37);

Protein name:

B-cell lymphoma 3 protein(BCL-3);

Alternative:

Proto-oncogene BCL3;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Component of a complex consisting of the NF-kappa-B p52-p52 homodimer and BCL3. Component of a complex consisting of the NF-kappa-B p50-p50 homodimer and BCL3. Interacts with N4BP2, COPS5 and PIR. Interacts with CYLD.

Function:

Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit. In the nucleus, acts as transcriptional activator that promotes transcription of NF-kappa-B target genes. Contributes to the regulation of cell proliferation.

Subcellular Location:

Nucleus Cytoplasm Cytoplasm perinuclear region Ubiquitination via 'Lys-63'-linked ubiquitin chains is required for nuclear accumulation.

Protein Attributes:

Sequence length:

454

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

454:

PGGS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.31210

STRING:

9606.ENSP00000164227

MIM:

109560

KEGG:

hsa:602

String:

P20749

Pfam:

PF00023

SMR:

P20749

Uniprot:

P20749

FOR

ELISA Kit for Human BCL-3

Cat.:

E1734h

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96T

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ELISA Kit for Human BCL-3

Cat.:

E1734m

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Packing:

96T

CLIA Kit for Human BCL-3

Cat.:

U1734h

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Manual:

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96T

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CLIA Kit for Human BCL-3

Cat.:

U1734m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human BCL-3

Cat.:

P1734Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human BCL-3

Cat.:

P1734Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human BCL-3

Protein for Human BCL-3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"The candidate proto-oncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control."
Ohno H. , Takimoto G. , McKeithan T.W.
Cell60:991-997(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Lung.
3.

"Genomic structure of the candidate proto-oncogene BCL3."
McKeithan T.W. , Ohno H. , Dickstein J. , Hume E.
Genomics24:120-126(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 87-454
tissue: Leukemia.
4.

"The oncoprotein Bcl-3 directly transactivates through kappa B motifs via association with DNA-binding p50B homodimers."
Bours V. , Franzoso G. , Azarenko V. , Park S. , Kanno T. , Brown K. , Siebenlist U.
Cell72:729-739(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;IDENTIFICATION IN A COMPLEX WITH NFKB2/P52
5.

"NF-kappaB p105 is a target of IkappaB kinases and controls signal induction of Bcl-3-p50 complexes."
Heissmeyer V. , Krappmann D. , Wulczyn F.G. , Scheidereit C.
EMBO J.18:4766-4778(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A COMPLEX WITH NFKB1/P50
6.

"The Bcl-3 oncoprotein acts as a bridging factor between NF-kappaB/Rel and nuclear co-regulators."
Dechend R. , Hirano F. , Lehmann K. , Heissmeyer V. , Ansieau S. , Wulczyn F.G. , Scheidereit C. , Leutz A.
Oncogene18:3316-3323(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH COPS5 AND PIR
7.

"Identification and characterization of BCL-3-binding protein: implications for transcription and DNA repair or recombination."
Watanabe N. , Wachi S. , Fujita T.
J. Biol. Chem.278:26102-26110(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH N4BP2
8.

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P. , Lasa M. , Polevoda B. , Gazquez C. , Elosegui-Artola A. , Kim D.S. , De Juan-Pardo E. , Demeyer K. , Hole K. , Larrea E. , Timmerman E. , Prieto J. , Arnesen T. , Sherman F. , Gevaert K. , Aldabe R.
Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
9.

"Crystal structure of the ankyrin repeat domain of Bcl-3: a unique member of the IkappaB protein family."
Michel F. , Soler-Lopez M. , Petosa C. , Cramer P. , Siebenlist U. , Muller C.W.
EMBO J.20:6180-6190(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.86 ANGSTROMS) OF 127-367
10.

"GSK3-mediated BCL-3 phosphorylation modulates its degradation and its oncogenicity."
Viatour P. , Dejardin E. , Warnier M. , Lair F. , Claudio E. , Bureau F. , Marine J.C. , Merville M.P. , Maurer U. , Green D. , Piette J. , Siebenlist U. , Bours V. , Chariot A.
Mol. Cell16:35-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-402 AND SER-406

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