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Index > Protein center > BSN(Gene name) > Human
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  • BSN (Gene name),
  • Protein bassoon (Protein name ),  BSN_HUMAN from NCBI database.
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  • Gene name:
    BSN(KIAA0434;ZNF231);
    Protein name:
    Protein bassoon;
    Alternative:
    Zinc finger protein 231;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with ERC2/CAST1, RIMS1 and UNC13A. Part of a complex consisting of ERC2, RIMS1 and BSN.
    Function:
    Is thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act through binding to ERC2/CAST1. Essential in regulated neurotransmitter release from a subset of brain glutamatergic synapses. Involved in the formation of the retinal photoreceptor ribbon synapses.
    Subcellular Location:
    Cytoplasm Cell junction synapse synaptosome Cytoplasm cytoskeleton Localized to the active zone of presynaptic density.
    Protein Attributes:
    Sequence length:
    3926
    Sequence:
    50:
    MGNEVSLEGG | AGDGPLPPGG | AGPGPGPGPG | PGAGKPPSAP | AGGGQLPAAG | 
    100:
    AARSTAVPPV | PGPGPGPGPG | PGPGSTSRRL | DPKEPLGNQR | AASPTPKQAS | 
    150:
    ATTPGHESPR | ETRAQGPAGQ | EADGPRRTLQ | VDSRTQRSGR | SPSVSPDRGS | 
    200:
    TPTSPYSVPQ | IAPLPSSTLC | PICKTSDLTS | TPSQPNFNTC | TQCHNKVCNQ | 
    250:
    CGFNPNPHLT | QVKEWLCLNC | QMQRALGMDM | TTAPRSKSQQ | QLHSPALSPA | 
    300:
    HSPAKQPLGK | PDQERSRGPG | GPQPGSRQAE | TARATSVPGP | AQAAAPPEVG | 
    350:
    RVSPQPPQPT | KPSTAEPRPP | AGEAPAKSAT | AVPAGLGATE | QTQEGLTGKL | 
    400:
    FGLGASLLTQ | ASTLMSVQPE | ADTQGQPAPS | KGTPKIVFND | ASKEAGPKPL | 
    450:
    GSGPGPGPAP | GAKTEPGARM | GPGSGPGALP | KTGGTTSPKH | GRAEHQAASK | 
    500:
    AAAKPKTMPK | ERAICPLCQA | ELNVGSKSPA | NYNTCTTCRL | QVCNLCGFNP | 
    550:
    TPHLVEKTEW | LCLNCQTKRL | LEGSLGEPTP | LPPPTSQQPP | VGAPHRASGT | 
    600:
    SPLKQKGPQG | LGQPSGPLPA | KASPLSTKAS | PLPSKASPQA | KPLRASEPSK | 
    650:
    TPSSVQEKKT | RVPTKAEPMP | KPPPETTPTP | ATPKVKSGVR | RAEPATPVVK | 
    700:
    AVPEAPKGGE | AEDLVGKPYS | QDASRSPQSL | SDTGYSSDGI | SSSQSEITGV | 
    750:
    VQQEVEQLDS | AGVTGPHPPS | PSEIHKVGSS | MRPLLQAQGL | APSERSKPLS | 
    800:
    SGTGEEQKQR | PHSLSITPEA | FDSDEELEDI | LEEDEDSAEW | RRRREQQDTA | 
    850:
    ESSDDFGSQL | RHDYVEDSSE | GGLSPLPPQP | PARAAELTDE | DFMRRQILEM | 
    900:
    SAEEDNLEED | DTATSGRGLA | KHGTQKGGPR | PRPEPSQEPA | ALPKRRLPHN | 
    950:
    ATTGYEELLP | EGGSAEATDG | SGTLQGGLRR | FKTIELNSTG | SYGHELDLGQ | 
    1000:
    GPDPSLDREP | ELEMESLTGS | PEDRSRGEHS | STLPASTPSY | TSGTSPTSLS | 
    1050:
    SLEEDSDSSP | SRRQRLEEAK | QQRKARHRSH | GPLLPTIEDS | SEEEELREEE | 
    1100:
    ELLREQEKMR | EVEQQRIRST | ARKTRRDKEE | LRAQRRRERS | KTPPSNLSPI | 
    1150:
    EDASPTEELR | QAAEMEELHR | SSCSEYSPSP | SLDSEAEALD | GGPSRLYKSG | 
    1200:
    SEYNLPTFMS | LYSPTETPSG | SSTTPSSGRP | LKSAEEAYEE | MMRKAELLQR | 
    1250:
    QQGQAAGARG | PHGGPSQPTG | PRGLGSFEYQ | DTTDREYGQA | AQPAAEGTPA | 
    1300:
    SLGAAVYEEI | LQTSQSIVRM | RQASSRDLAF | AEDKKKEKQF | LNAESAYMDP | 
    1350:
    MKQNGGPLTP | GTSPTQLAAP | VSFSTPTSSD | SSGGRVIPDV | RVTQHFAKET | 
    1400:
    QDPLKLHSSP | ASPSSASKEI | GMPFSQGPGT | PATTAVAPCP | AGLPRGYMTP | 
    1450:
    ASPAGSERSP | SPSSTAHSYG | HSPTTANYGS | QTEDLPQAPS | GLAAAGRAAR | 
    1500:
    EKPLSASDGE | GGTPQPSRAY | SYFASSSPPL | SPSSPSESPT | FSPGKMGPRA | 
    1550:
    TAEFSTQTPS | PAPASDMPRS | PGAPTPSPMV | AQGTQTPHRP | STPRLVWQES | 
    1600:
    SQEAPFMVIT | LASDASSQTR | MVHASASTSP | LCSPTETQPT | THGYSQTTPP | 
    1650:
    SVSQLPPEPP | GPPGFPRVPS | AGADGPLALY | GWGALPAENI | SLCRISSVPG | 
    1700:
    TSRVEPGPRT | PGTAVVDLRT | AVKPTPIILT | DQGMDLTSLA | VEARKYGLAL | 
    1750:
    DPIPGRQSTA | VQPLVINLNA | QEHTFLATAT | TVSITMASSV | FMAQQKQPVV | 
    1800:
    YGDPYQSRLD | FGQGGGSPVC | LAQVKQVEQA | VQTAPYRSGP | RGRPREAKFA | 
    1850:
    RYNLPNQVAP | LARRDVLITQ | MGTAQSIGLK | PGPVPEPGAE | PHRATPAELR | 
    1900:
    SHALPGARKP | HTVVVQMGEG | TAGTVTTLLP | EEPAGALDLT | GMRPESQLAC | 
    1950:
    CDMVYKLPFG | SSCTGTFHPA | PSVPEKSMAD | AAPPGQSSSP | FYGPRDPEPP | 
    2000:
    EPPTYRAQGV | VGPGPHEEQR | PYPQGLPGRL | YSSMSDTNLA | EAGLNYHAQR | 
    2050:
    IGQLFQGPGR | DSAMDLSSLK | HSYSLGFADG | RYLGQGLQYG | SVTDLRHPTD | 
    2100:
    LLAHPLPMRR | YSSVSNIYSD | HRYGPRGDAV | GFQEASLAQY | SATTAREISR | 
    2150:
    MCAALNSMDQ | YGGRHGSGGG | GPDLVQYQPQ | HGPGLSAPQS | LVPLRPGLLG | 
    2200:
    NPTFPEGHPS | PGNLAQYGPA | AGQGTAVRQL | LPSTATVRAA | DGMIYSTINT | 
    2250:
    PIAATLPITT | QPASVLRPMV | RGGMYRPYAS | GGITAVPLTS | LTRVPMIAPR | 
    2300:
    VPLGPTGLYR | YPAPSRFPIA | SSVPPAEGPV | YLGKPAAAKA | PGAGGPSRPE | 
    2350:
    MPVGAAREEP | LPTTTPAAIK | EAAGAPAPAP | LAGQKPPADA | APGGGSGALS | 
    2400:
    RPGFEKEEAS | QEERQRKQQE | QLLQLERERV | ELEKLRQLRL | QEELERERVE | 
    2450:
    LQRHREEEQL | LVQRELQELQ | TIKHHVLQQQ | QEERQAQFAL | QREQLAQQRL | 
    2500:
    QLEQIQQLQQ | QLQQQLEEQK | QRQKAPFPAA | CEAPGRGPPL | AAAELAQNGQ | 
    2550:
    YWPPLTHAAF | IAMAGPEGLG | QPREPVLHRG | LPSSASDMSL | QTEEQWEASR | 
    2600:
    SGIKKRHSMP | RLRDACELES | GTEPCVVRRI | ADSSVQTDDE | DGESRYLLSR | 
    2650:
    RRRARRSADC | SVQTDDEDSA | EWEQPVRRRR | SRLPRHSDSG | SDSKHDATAS | 
    2700:
    SSSAAATVRA | MSSVGIQTIS | DCSVQTEPDQ | LPRVSPAIHI | TAATDPKVEI | 
    2750:
    VRYISAPEKT | GRGESLACQT | EPDGQAQGVA | GPQLVGPTAI | SPYLPGIQIV | 
    2800:
    TPGPLGRFEK | KKPDPLEIGY | QAHLPPESLS | QLVSRQPPKS | PQVLYSPVSP | 
    2850:
    LSPHRLLDTS | FASSERLNKA | HVSPQKHFTA | DSALRQQTLP | RPMKTLQRSL | 
    2900:
    SDPKPLSPTA | EESAKERFSL | YQHQGGLGSQ | VSALPPNSLV | RKVKRTLPSP | 
    2950:
    PPEEAHLPLA | GQASPQLYAA | SLLQRGLTGP | TTVPATKASL | LRELDRDLRL | 
    3000:
    VEHESTKLRK | KQAELDEEEK | EIDAKLKYLE | LGITQRKESL | AKDRGGRDYP | 
    3050:
    PLRGLGEHRD | YLSDSELNQL | RLQGCTTPAG | QFVDFPATAA | APATPSGPTA | 
    3100:
    FQQPRFQPPA | PQYSAGSGGP | TQNGFPAHQA | PTYPGPSTYP | APAFPPGASY | 
    3150:
    PAEPGLPNQQ | AFRPTGHYAG | QTPMPTTQST | LFPVPADSRA | PLQKPRQTSL | 
    3200:
    ADLEQKVPTN | YEVIASPVVP | MSSAPSETSY | SGPAVSSGYE | QGKVPEVPRA | 
    3250:
    GDRGSVSQSP | APTYPSDSHY | TSLEQNVPRN | YVMIDDISEL | TKDSTSTAPD | 
    3300:
    SQRLEPLGPG | SSGRPGKEPG | EPGVLDGPTL | PCCYARGEEE | SEEDSYDPRG | 
    3350:
    KGGHLRSMES | NGRPASTHYY | GDSDYRHGAR | VEKYGPGPMG | PKHPSKSLAP | 
    3400:
    AAISSKRSKH | RKQGMEQKIS | KFSPIEEAKD | VESDLASYPP | PAVSSSLVSR | 
    3450:
    GRKFQDEITY | GLKKNVYEQQ | KYYGMSSRDA | VEDDRIYGGS | SRSRAPSAYS | 
    3500:
    GEKLSSHDFS | GWGKGYERER | EAVERLQKAG | PKPSSLSMAH | SRVRPPMRSQ | 
    3550:
    ASEEESPVSP | LGRPRPAGGP | LPPGGDTCPQ | FCSSHSMPDV | QEHVKDGPRA | 
    3600:
    HAYKREEGYI | LDDSHCVVSD | SEAYHLGQEE | TDWFDKPRDA | RSDRFRHHGG | 
    3650:
    HAVSSSSQKR | GPARHSYHDY | DEPPEEGLWP | HDEGGPGRHA | SAKEHRHGDH | 
    3700:
    GRHSGRHTGE | EPGRRAAKPH | ARDLGRHEAR | PHSQPSSAPA | MPKKGQPGYP | 
    3750:
    SSAEYSQPSR | ASSAYHHASD | SKKGSRQAHS | GPAALQSKAE | PQAQPQLQGR | 
    3800:
    QAAPGPQQSQ | SPSSRQIPSG | AASRQPQTQQ | QQQGLGLQPP | QQALTQARLQ | 
    3850:
    QQSQPTTRGS | APAASQPAGK | PQPGPSTATG | PQPAGPPRAE | QTNGSKGTAK | 
    3900:
    APQQGRAPQA | QPAPGPGPAG | VKAGARPGGT | PGAPAGQPGA | DGESVFSKIL | 
    3926:
    PGGAAEQAGK | LTEAVSAFGK | KFSSFW
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    MIM:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Protein bassoon
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    E12516h
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    ELISA Kit for Human Protein bassoon
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    E12516m
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    Packing:
    96T
    ELISA Kit for Human Protein bassoon
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    E12516r
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    96T
    CLIA Kit for Human Protein bassoon
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    U12516m
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    Packing:
    96T
    CLIA Kit for Human Protein bassoon
    Cat.:
    U12516r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Protein bassoon
    Cat.:
    U12516h
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Protein bassoon
    Cat.:
    P12516Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Protein bassoon
    Polyclonal Antibody for Human Protein bassoon
    Monoclonal Antibody for Human Protein bassoon
    Monoclonal Antibody for Human Protein bassoon
    Monoclonal Antibody for Human Protein bassoon
    Protein for Human Protein bassoon
    Protein for Human Protein bassoon
    Protein for Human Protein bassoon

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    References
    1. 1.
      "Cloning and mapping of ZNF231, a novel brain-specific gene encoding neuronal double zinc finger protein whose expression is enhanced in a neurodegenerative disorder, multiple system atrophy."
      Hashida H. , Goto J. , Zhao N. , Takahashi N. , Hirai M. , Kanazawa I. , Sakaki Y.
      Genomics54:50-58(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;VARIANT THR-3863
    2. 2.
      "The DNA sequence, annotation and analysis of human chromosome 3."
      Muzny D.M. , Scherer S.E. , Kaul R. , Wang J. , Yu J. , Sudbrak R. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , more...
      Nature440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The presynaptic cytomatrix protein Bassoon: sequence and chromosomal localization of the human BSN gene."
      Winter C. , tom Dieck S. , Boeckers T. , Bockmann J. , Kaempf U. , Sanmarti-Vila L. , Langnaese K. , Altrock W. , Stumm M. , Soyke A. , Wieacker P. , Garner C.C. , Gundelfinger E.D.
      Genomics57:389-397(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 77-3926;VARIANT THR-3863
    4. 4.
      "Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro."
      Ishikawa K. , Nagase T. , Nakajima D. , Seki N. , Ohira M. , Miyajima N. , Tanaka A. , Kotani H. , Nomura N. , Ohara O.
      DNA Res.4:307-313(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2357-3926;VARIANT THR-3863
      tissue: Brain.
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