CD163 ELISA Kit for Human(Homo sapiens) | EIAab.comCD163 ELISA Kit for Human(Homo sapiens)

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CD163 (Gene name),

Scavenger receptor cysteine-rich type 1 protein M130 (Protein name ), C163A_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CD163(M130);

Protein name:

Scavenger receptor cysteine-rich type 1 protein M130;

Alternative:

Hemoglobin scavenger receptor;

CD:

CD163;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with CSNK2B.

Function:

After shedding, the soluble form (sCD163) may play an anti-inflammatory role, and may be a valuable diagnostic parameter for monitoring macrophage activation in inflammatory conditions.

Subcellular Location:

Cell membrane Single-pass type I membrane protein Isoform 1 and isoform 2 show a lower surface expression when expressed in cells.

Protein Attributes:

Sequence length:

1156

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

1000:

1050:

1100:

1150:

1156:

KENGNL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q86VB7

KEGG:

hsa:9332

UniGene:

Hs.504641

STRING:

9606.ENSP00000352071

Pfam:

PF00530

MIM:

605545

SMR:

Q86VB7

Uniprot:

Q86VB7

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ELISA Kit for Human Scavenger receptor cysteine-rich type 1 protein M130

Cat.:

E1726h

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96T

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ELISA Kit for Human Scavenger receptor cysteine-rich type 1 protein M130

Cat.:

E1726m

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96T

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ELISA Kit for Human Scavenger receptor cysteine-rich type 1 protein M130

Cat.:

E1726d

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96T

ELISA Kit for Human Scavenger receptor cysteine-rich type 1 protein M130

Cat.:

E1726b

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96T

ELISA Kit for Human Scavenger receptor cysteine-rich type 1 protein M130

Cat.:

E1726p

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Packing:

96T

CLIA Kit for Human Scavenger receptor cysteine-rich type 1 protein M130

Cat.:

U1726b

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MSDS:

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Packing:

96T

CLIA Kit for Human Scavenger receptor cysteine-rich type 1 protein M130

Cat.:

U1726d

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Scavenger receptor cysteine-rich type 1 protein M130

Cat.:

U1726p

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Scavenger receptor cysteine-rich type 1 protein M130

Cat.:

U1726h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

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CLIA Kit for Human Scavenger receptor cysteine-rich type 1 protein M130

Cat.:

U1726m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Scavenger receptor cysteine-rich type 1 protein M130

Cat.:

P1726Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Scavenger receptor cysteine-rich type 1 protein M130

Cat.:

P1726Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Scavenger receptor cysteine-rich type 1 protein M130

Protein for Human Scavenger receptor cysteine-rich type 1 protein M130

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"A new macrophage differentiation antigen which is a member of the scavenger receptor superfamily."
Law S.K.A. , Micklem K.J. , Shaw J.M. , Zhang X.-P. , Dong Y. , Willis A.C. , Mason D.Y.
Eur. J. Immunol.23:2320-2325(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3 AND 4);VARIANT VAL-342
2.

"Genomic organization and chromosomal localization of the human CD163 (M130) gene: a member of the scavenger receptor cysteine-rich superfamily."
Ritter M. , Buechler C. , Langmann T. , Schmitz G.
Biochem. Biophys. Res. Commun.260:466-474(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT VAL-342
3.

"Scavenger receptor cd163 is a cell permissive factor for infection with porcine reproductive and respiratory syndrome viruses."
Welch S.-K.W. , Calvert J.G. , Slade D.E. , Shields S.L.
Submitted (2005-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);VARIANT VAL-342
4.

"The finished DNA sequence of human chromosome 12."
Scherer S.E. , Muzny D.M. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , Jackson A. , Khan Z.M. , Kovar-Smith C. , Lewis L.R. , more...
Nature440:346-351(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT VAL-342
tissue: Spleen.
6.

"Shedding of CD163, a novel regulatory mechanism for a member of the scavenger receptor cysteine-rich family."
Droste A. , Sorg C. , Hogger P.
Biochem. Biophys. Res. Commun.256:110-113(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CLEAVAGE
7.

"Regulation of CD 163 on human macrophages: cross-linking of CD163 induces signaling and activation."
Van den Heuvel M.M. , Tensen C.P. , van As J.H. , Van den Berg T.K. , Fluitsma D.M. , Dijkstra C.D. , Dopp E.A. , Droste A. , Van Gaalen F.A. , Sorg C. , Hoegger P. , Beelen R.H.J.
J. Leukoc. Biol.66:858-866(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY;INDUCTION;SUBCELLULAR LOCATION
8.

"Regulation of scavenger receptor CD163 expression in human monocytes and macrophages by pro- and antiinflammatory stimuli."
Buechler C. , Ritter M. , Orso E. , Langmann T. , Klucken J. , Schmitz G.
J. Leukoc. Biol.67:97-103(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION;SUBCELLULAR LOCATION
9.

"Interaction of CD163 with the regulatory subunit of casein kinase II (CKII) and dependence of CD163 signaling on CKII and protein kinase C."
Ritter M. , Buechler C. , Kapinsky M. , Schmitz G.
Eur. J. Immunol.31:999-1009(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;PHOSPHORYLATION;MUTAGENESIS OF THR-1072 AND SER-1084;INTERACTION WITH CSNK2B
10.

"Identification of the haemoglobin scavenger receptor."
Kristiansen M. , Graversen J.H. , Jacobsen C. , Sonne O. , Hoffman H.-J. , Law S.K.A. , Moestrup S.K.
Nature409:198-201(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY;BIOPHYSICOCHEMICAL PROPERTIES;IDENTIFICATION BY MASS SPECTROMETRY
11.

"Elevated levels of soluble CD163 in sera and fluids from rheumatoid arthritis patients and inhibition of the shedding of CD163 by TIMP-3."
Matsushita N. , Kashiwagi M. , Wait R. , Nagayoshi R. , Nakamura M. , Matsuda T. , Hogger P. , Guyre P.M. , Nagase H. , Matsuyama T.
Clin. Exp. Immunol.130:156-161(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CLEAVAGE
12.

"Only the soluble form of the scavenger receptor CD163 acts inhibitory on phorbol ester-activated T-lymphocytes, whereas membrane-bound protein has no effect."
Frings W. , Dreier J. , Sorg C.
FEBS Lett.526:93-96(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
13.

"Endotoxin induces rapid metalloproteinase-mediated shedding followed by up-regulation of the monocyte hemoglobin scavenger receptor CD163."
Hintz K.A. , Rassias A.J. , Wardwell K. , Moss M.L. , Morganelli P.M. , Pioli P.A. , Givan A.L. , Wallace P.K. , Yeager M.P. , Guyre P.M.
J. Leukoc. Biol.72:711-717(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MISCELLANEOUS
14.

"CD163: a regulated hemoglobin scavenger receptor with a role in the anti-inflammatory response."
Moestrup S.K. , Moller H.J.
Ann. Med.36:347-354(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: RELEVANCE AS DISEASE MARKER IN INFLAMMATORY CONDITIONS
15.

"Molecular characterization of the haptoglobin.hemoglobin receptor CD163. Ligand binding properties of the scavenger receptor cysteine-rich domain region."
Madsen M. , Moller H.J. , Nielsen M.J. , Jacobsen C. , Graversen J.H. , van den Berg T. , Moestrup S.K.
J. Biol. Chem.279:51561-51567(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DOMAIN;CLEAVAGE SITES
16.

"Cross-linking of FcgammaR triggers shedding of the hemoglobin-haptoglobin scavenger receptor CD163."
Sulahian T.H. , Pioli P.A. , Wardwell K. , Guyre P.M.
J. Leukoc. Biol.76:271-277(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CLEAVAGE
17.

"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-105
tissue: Plasma.
18.

"The macrophage scavenger receptor CD163: endocytic properties of cytoplasmic tail variants."
Nielsen M.J. , Madsen M. , Moller H.J. , Moestrup S.K.
J. Leukoc. Biol.79:837-845(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;MUTAGENESIS OF TYR-1096;TISSUE SPECIFICITY
19.

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-105; ASN-140; ASN-767 AND ASN-1027
tissue: Liver.
20.

"A strategy for precise and large scale identification of core fucosylated glycoproteins."
Jia W. , Lu Z. , Fu Y. , Wang H.P. , Wang L.H. , Chi H. , Yuan Z.F. , Zheng Z.B. , Song L.N. , Han H.H. , Liang Y.M. , Wang J.L. , Cai Y. , Zhang Y.K. , Deng Y.L. , Ying W.T. , He S.M. , Qian X.H.
Mol. Cell. Proteomics8:913-923(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-105

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