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Index > Protein center > C1galt1c1(Gene name) > Mouse
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  • C1galt1c1 (Gene name),
  • C1GALT1-specific chaperone 1 (Protein name ),  C1GLC_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    C1galt1c1(Cosmc);
    Protein name:
    C1GALT1-specific chaperone 1;
    Alternative:
    Core 1 beta3-galactosyltransferase-specific molecular chaperone;Core 1 beta1,3-galactosyltransferase 2(C1Gal-T2;C1GalT2;Core 1 beta3-Gal-T2;mC1Gal-T2);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Associates with core 1 beta-3-galactosyltransferase (C1GALT1), probably not with the soluble active form.
    Function:
    Probable chaperone required for the generation of 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1).
    Subcellular Location:
    Membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    316
    Sequence:
    50:
    MLSESSSFLK | GVMLGSIFCA | LITMLGHIRI | GNRMHHHEHH | HLQAPNKDDI | 
    100:
    SKISEAERME | LSKSFRVYCI | VLVKPKDVSL | WAAVKETWTK | HCDKAEFFSS | 
    150:
    ENVKVFESIN | MDTNDMWLMM | RKAYKYAYDQ | YRDQYNWFFL | ARPTTFAVIE | 
    200:
    NLKYFLLKKD | QSQPFYLGHT | VKSGDLEYVS | VDGGIVLSIE | SMKRLNSLLS | 
    250:
    VPEKCPEQGG | MIWKISEDKQ | LAVCLKYAGV | FAENAEDADG | KDVFNTKSVG | 
    300:
    LFIKEAMTNQ | PNQVVEGCCS | DMAVTFNGLT | PNQMHVMMYG | VYRLRAFGHV | 
    316:
    FNDALVFLPP | NGSEND
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse C1GALT1-specific chaperone 1
    ELISA Kit for Mouse C1GALT1-specific chaperone 1
    ELISA Kit for Mouse C1GALT1-specific chaperone 1
    ELISA Kit for Mouse C1GALT1-specific chaperone 1
    CLIA Kit for Mouse C1GALT1-specific chaperone 1
    CLIA Kit for Mouse C1GALT1-specific chaperone 1
    CLIA Kit for Mouse C1GALT1-specific chaperone 1
    CLIA Kit for Mouse C1GALT1-specific chaperone 1
    Polyclonal Antibody for Mouse C1GALT1-specific chaperone 1
    Polyclonal Antibody for Mouse C1GALT1-specific chaperone 1
    Polyclonal Antibody for Mouse C1GALT1-specific chaperone 1
    Polyclonal Antibody for Mouse C1GALT1-specific chaperone 1
    Monoclonal Antibody for Mouse C1GALT1-specific chaperone 1
    Monoclonal Antibody for Mouse C1GALT1-specific chaperone 1
    Monoclonal Antibody for Mouse C1GALT1-specific chaperone 1
    Monoclonal Antibody for Mouse C1GALT1-specific chaperone 1
    Protein for Mouse C1GALT1-specific chaperone 1
    Protein for Mouse C1GALT1-specific chaperone 1
    Protein for Mouse C1GALT1-specific chaperone 1
    Protein for Mouse C1GALT1-specific chaperone 1

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    Precision
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    Linearity
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    References
    1. 1.
      "Growth suppression of Escherichia coli by induction of expression of mammalian genes with transmembrane or ATPase domains."
      Inoue S. , Sano H. , Ohta M.
      Biochem. Biophys. Res. Commun.268:553-561(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    2. 2.
      "A unique molecular chaperone Cosmc required for activity of the mammalian core 1 beta 3-galactosyltransferase."
      Ju T. , Cummings R.D.
      Proc. Natl. Acad. Sci. U.S.A.99:16613-16618(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Molecular cloning of a UDP-Gal: GalNAcalpha-peptide mouse beta1,3-galactosyltransferase (mC1Gal-T2), an enzyme synthesizing a core 1 structure of O-glycan."
      Kudo T. , Takayama Y. , Narimatsu H.
      Submitted (2002-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: ICR.
      tissue: Liver.
    4. 4.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Small intestine.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: 129.
      tissue: Mammary tumor.
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