Gene name:
C1galt1 (Plt1) ;
Protein name:
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 ;
Alternative:
Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1 ;Core 1 O-glycan T-synthase (T-syn) ;Core 1 beta1,3-galactosyltransferase 1 (C1GalT1;Core 1 beta3-Gal-T1) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Homodimer; disulfide-linked. Interacts with the C1GALT1C1 chaperone; required for galactosyltransferase activity.
Function:
Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development.
Subcellular Location:
Membrane
Single-pass type II membrane protein
Protein Attributes:
50:
MASKSWLNFL | VFLCGSAIGF | FLCSQLLSIL | LREEAAIQPN | MLHNDPHARH |
100:
SDDNGHSHLK | GQMNFNADSS | QHKDENIDVA | ENLYQKVKIL | CWVMTSPQNL |
150:
EKKAKHVKAT | WAQRCNKVLF | MSSEENQDFP | TVGLKTKEGR | EQLYWKTIKA |
200:
FQYVHDHYLE | DADWFMKADD | DTYVIVDNLR | WLLSKYNPEQ | PIYFGRRFKP |
250:
YVKQGYMSGG | AGYVLSKEAL | RRFVNAFKTE | KCTHSSSIED | LALGRCMEII |
300:
NVEAGDSRDT | IGKETFHPFV | PEHHLIKGYL | PKTFWYWNYN | YYPPIEGPGC |
350:
CSDIAVSFHY | VDGTTMYELE | YLVYHLRPYG | YLYRYQPALP | ENILKEINQV |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Chicken
Mouse
Human
Rat
ELISA Kit for Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
ELISA Kit for Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
ELISA Kit for Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
ELISA Kit for Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
ELISA Kit for Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
CLIA Kit for Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
CLIA Kit for Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
CLIA Kit for Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
CLIA Kit for Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
CLIA Kit for Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Polyclonal Antibody for Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Polyclonal Antibody for Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Polyclonal Antibody for Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Polyclonal Antibody for Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Polyclonal Antibody for Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Monoclonal Antibody for Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Monoclonal Antibody for Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Monoclonal Antibody for Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Monoclonal Antibody for Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Monoclonal Antibody for Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Protein for Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Protein for Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Protein for Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Protein for Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Protein for Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6NCr .
strain :
FVB/N .
tissue :
Hematopoietic stem cell .
tissue :
Kidney .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DISRUPTION PHENOTYPE;FUNCTION;TISSUE SPECIFICITY
4.
"Thrombocytopenia and kidney disease in mice with a mutation in the C1galt1 gene."
Alexander W.S.
,
Viney E.M.
,
Zhang J.-G.
,
Metcalf D.
,
Kauppi M.
,
Hyland C.D.
,
Carpinelli M.R.
,
Stevenson W.
,
Croker B.A.
,
Hilton A.A.
,
Ellis S.
,
Selan C.
,
Nandurkar H.H.
,
Goodnow C.C.
,
Kile B.T.
,
Nicola N.A.
,
Roberts A.W.
,
Hilton D.J.
Proc. Natl. Acad. Sci. U.S.A.103:16442-16447(2006)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;MUTAGENESIS OF TYR-321
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-235;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .