Protein name:
Complement C1q subcomponent subunit C ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
C1 is a calcium-dependent trimolecular complex of C1q, R and S in the molar ration of 1:2:2. C1q subcomponent is composed of nine subunits, six of which are disulfide-linked dimers of the A and B chains, and three of which are disulfide-linked dimers of the C chain.
Function:
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
Subcellular Location:
Secreted
Protein Attributes:
50:
MDVGPSSLPH | LGLKLLLLLL | LLPLRGQANT | GCYGIPGMPG | LPGAPGKDGY |
100:
DGLPGPKGEP | GIPAIPGIRG | PKGQKGEPGL | PGHPGKNGPM | GPPGMPGVPG |
150:
PMGIPGEPGE | EGRYKQKFQS | VFTVTRQTHQ | PPAPNSLIRF | NAVLTNPQGD |
200:
YDTSTGKFTC | KVPGLYYFVY | HASHTANLCV | LLYRSGVKVV | TFCGHTSKTN |
245:
QVNSGGVLLR | LQVGEEVWLA | VNDYYDMVGI | QGSDSVFSGF | LLFPD
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Human Complement C1q subcomponent subunit C
ELISA Kit for Human Complement C1q subcomponent subunit C
ELISA Kit for Human Complement C1q subcomponent subunit C
CLIA Kit for Human Complement C1q subcomponent subunit C
CLIA Kit for Human Complement C1q subcomponent subunit C
CLIA Kit for Human Complement C1q subcomponent subunit C
Polyclonal Antibody for Human Complement C1q subcomponent subunit C
Polyclonal Antibody for Human Complement C1q subcomponent subunit C
Polyclonal Antibody for Human Complement C1q subcomponent subunit C
Monoclonal Antibody for Human Complement C1q subcomponent subunit C
Monoclonal Antibody for Human Complement C1q subcomponent subunit C
Monoclonal Antibody for Human Complement C1q subcomponent subunit C
Protein for Human Complement C1q subcomponent subunit C
Protein for Human Complement C1q subcomponent subunit C
Protein for Human Complement C1q subcomponent subunit C
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Monocyte .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Brain .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 29-122;HYDROXYLATION AT PRO-36; PRO-39; PRO-42; PRO-45; PRO-54; PRO-63; LYS-75; PRO-81; PRO-93; PRO-96; PRO-99 AND PRO-105
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS) OF 117-245
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW ON C1Q DEFICIENCY
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT C1QD ARG-34