Ciita ELISA Kit for Mouse(Mus musculus) | EIAab.comCiita ELISA Kit for Mouse(Mus musculus)

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Ciita (Gene name),

MHC class II transactivator (Protein name ), C2TA_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Ciita(C2ta;Mhc2ta);

Protein name:

MHC class II transactivator(CIITA);

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with ZXDA and ZXDC.

Function:

Essential for transcriptional activity of the HLA class II promoter; activation is via the proximal promoter. No DNA binding of in vitro translated CIITA was detected. May act in a coactivator-like fashion through protein-protein interactions by contacting factors binding to the proximal MHC class II promoter, to elements of the transcription machinery, or both. Alternatively it may activate HLA class II transcription by modifying proteins that bind to the MHC class II promoter.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

1155

Sequence:

50:

100:

150:

200:

250:

300:

350:

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650:

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800:

850:

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950:

1000:

1050:

1100:

1150:

1155:

RISLR

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P79621

String:

P79621

Pfam:

PF12799

UniGene:

Mm.249560

KEGG:

mmu:12265

Uniprot:

P79621

FOR

ELISA Kit for Mouse CIITA

CLIA Kit for Mouse CIITA

Polyclonal Antibody for Mouse CIITA

Monoclonal Antibody for Mouse CIITA

Protein for Mouse CIITA

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Expression of MHC class II molecules in different cellular and functional compartments is controlled by differential usage of multiple promoters of the transactivator CIITA."
Muhlethaler-Mottet A. , Otten L.A. , Steimle V. , Mach B.
EMBO J.16:2851-2860(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORMS 1; 2 AND 3);TISSUE SPECIFICITY;INDUCTION
strain: BALB/c.
2.

"Mouse class II transactivator: cDNA sequence and amino acid comparison with the human class II transactivator."
Sims T.N. , Elliott J.F. , Ramassar V. , Denney D.W. Jr. , Halloran P.F.
Immunogenetics45:220-222(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
strain: NOD.
tissue: Spleen.
3.

"Interferon gamma (IFNgamma) gene transfer of an EMT6 tumor that is poorly responsive to IFNgamma stimulation: increase in tumor immunogenicity is accompanied by induction of a mouse class II transactivator and class II MHC."
Panelli M.C. , Wang E. , Shen S. , Schluter S.F. , Bernstein R.M. , Hersh E.M. , Stopeck A. , Gangavalli R. , Barber J. , Jolly D. , Akporiaye E.T.
Cancer Immunol. Immunother.42:99-107(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 955-1097
strain: BALB/c.
tissue: Thymus.

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