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Index > Protein center > CACNA2D1(Gene name) > Rabbit
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  • CACNA2D1 (Gene name),
  • Voltage-dependent calcium channel subunit alpha-2/delta-1 (Protein name ),  CA2D1_RABIT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CACNA2D1(CACNL2A;CCHL2A);
    Protein name:
    Voltage-dependent calcium channel subunit alpha-2/delta-1;
    Alternative:
    Voltage-gated calcium channel subunit alpha-2/delta-1;
    Organism:
    Rabbit (Oryctolagus cuniculus). 
    General Annotation
    Sub Unit:
    Dimer formed of alpha-2-1 and delta-1 chains; disulfide-linked. Voltage-dependent calcium channels are multisubunit complexes, consisting of alpha-1 (CACNA1), alpha-2 (CACNA2D), beta (CACNB) and delta (CACNA2D) subunits in a 1:1:1:1 ratio.
    Function:
    The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    1106
    Sequence:
    50:
    MAAGRPLAWT | LTLWQAWLIL | IGPSSEEPFP | SAVTIKSWVD | KMQEDLVTLA | 
    100:
    KTASGVHQLV | DIYEKYQDLY | TVEPNNARQL | VEIAARDIEK | LLSNRSKALV | 
    150:
    RLALEAEKVQ | AAHQWREDFA | SNEVVYYNAK | DDLDPEKNDS | EPGSQRIKPV | 
    200:
    FIDDANFRRQ | VSYQHAAVHI | PTDIYEGSTI | VLNELNWTSA | LDDVFKKNRE | 
    250:
    EDPSLLWQVF | GSATGLARYY | PASPWVDNSR | TPNKIDLYDV | RRRPWYIQGA | 
    300:
    ASPKDMLILV | DVSGSVSGLT | LKLIRTSVSE | MLETLSDDDF | VNVASFNSNA | 
    350:
    QDVSCFQHLV | QANVRNKKVL | KDAVNNITAK | GITDYKKGFS | FAFEQLLNYN | 
    400:
    VSRANCNKII | MLFTDGGEER | AQEIFAKYNK | DKKVRVFTFS | VGQHNYDRGP | 
    450:
    IQWMACENKG | YYYEIPSIGA | IRINTQEYLD | VLGRPMVLAG | DKAKQVQWTN | 
    500:
    VYLDALELGL | VITGTLPVFN | ITGQFENKTN | LKNQLILGVM | GVDVSLEDIK | 
    550:
    RLTPRFTLCP | NGYYFAIDPN | GYVLLHPNLQ | PKPIGVGIPT | INLRKRRPNV | 
    600:
    QNPKSQEPVT | LDFLDAELEN | DIKVEIRNKM | IDGESGEKTF | RTLVKSQDER | 
    650:
    YIDKGNRTYT | WTPVNGTDYS | SLALVLPTYS | FYYIKAKIEE | TITQARYSET | 
    700:
    LKPDNFEESG | YTFLAPRDYC | SDLKPSDNNT | EFLLNFNEFI | DRKTPNNPSC | 
    750:
    NTDLINRVLL | DAGFTNELVQ | NYWSKQKNIK | GVKARFVVTD | GGITRVYPKE | 
    800:
    AGENWQENPE | TYEDSFYKRS | LDNDNYVFTA | PYFNKSGPGA | YESGIMVSKA | 
    850:
    VEIYIQGKLL | KPAVVGIKID | VNSWIENFTK | TSIRDPCAGP | VCDCKRNSDV | 
    900:
    MDCVILDDGG | FLLMANHDDY | TNQIGRFFGE | IDPSLMRHLV | NISVYAFNKS | 
    950:
    YDYQSVCEPG | AAPKQGAGHR | SAYVPSIADI | LQIGWWATAA | AWSILQQFLL | 
    1000:
    SLTFPRLLEA | ADMEDDDFTA | SMSKQSCITE | QTQYFFDNDS | KSFSGVLDCG | 
    1050:
    NCSRIFHVEK | LMNTNLIFIM | VESKGTCPCD | TRLLIQAEQT | SDGPDPCDMV | 
    1100:
    KQPRYRKGPD | VCFDNNVLED | YTDCGGVSGL | NPSLWSIIGI | QFVLLWLVSG | 
    1106:
    SRHCLL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rabbit Voltage-dependent calcium channel subunit alpha-2/delta-1
    ELISA Kit for Rabbit Voltage-dependent calcium channel subunit alpha-2/delta-1
    ELISA Kit for Rabbit Voltage-dependent calcium channel subunit alpha-2/delta-1
    ELISA Kit for Rabbit Voltage-dependent calcium channel subunit alpha-2/delta-1
    CLIA Kit for Rabbit Voltage-dependent calcium channel subunit alpha-2/delta-1
    CLIA Kit for Rabbit Voltage-dependent calcium channel subunit alpha-2/delta-1
    CLIA Kit for Rabbit Voltage-dependent calcium channel subunit alpha-2/delta-1
    CLIA Kit for Rabbit Voltage-dependent calcium channel subunit alpha-2/delta-1
    Polyclonal Antibody for Rabbit Voltage-dependent calcium channel subunit alpha-2/delta-1
    Polyclonal Antibody for Rabbit Voltage-dependent calcium channel subunit alpha-2/delta-1
    Polyclonal Antibody for Rabbit Voltage-dependent calcium channel subunit alpha-2/delta-1
    Polyclonal Antibody for Rabbit Voltage-dependent calcium channel subunit alpha-2/delta-1
    Monoclonal Antibody for Rabbit Voltage-dependent calcium channel subunit alpha-2/delta-1
    Monoclonal Antibody for Rabbit Voltage-dependent calcium channel subunit alpha-2/delta-1
    Monoclonal Antibody for Rabbit Voltage-dependent calcium channel subunit alpha-2/delta-1
    Monoclonal Antibody for Rabbit Voltage-dependent calcium channel subunit alpha-2/delta-1
    Protein for Rabbit Voltage-dependent calcium channel subunit alpha-2/delta-1
    Protein for Rabbit Voltage-dependent calcium channel subunit alpha-2/delta-1
    Protein for Rabbit Voltage-dependent calcium channel subunit alpha-2/delta-1
    Protein for Rabbit Voltage-dependent calcium channel subunit alpha-2/delta-1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Sequence and expression of mRNAs encoding the alpha 1 and alpha 2 subunits of a DHP-sensitive calcium channel."
      Ellis S.B. , Williams M.E. , Ways N.R. , Brenner R. , Sharp A.H. , Leung A.T. , Campbell K.P. , McKenna E. , Koch W.J. , Hui A. , Schwartz A. , Harpold M.M.
      Science241:1661-1664(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Subunit composition of the purified dihydropyridine binding protein from skeletal muscle."
      Hamilton S.L. , Hawkes M.J. , Brush K. , Cook R. , Chang R.J. , Smilowitz H.M.
      Biochemistry28:7820-7828(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 27-47
    3. 3.
      "Structural characterization of the dihydropyridine-sensitive calcium channel alpha 2-subunit and the associated delta peptides."
      Jay S.D. , Sharp A.H. , Kahl S.D. , Vedvick T.S. , Harpold M.M. , Campbell K.P.
      J. Biol. Chem.266:3287-3293(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 961-973
    4. 4.
      "Subunits of purified calcium channels. Alpha 2 and delta are encoded by the same gene."
      de Jongh K.S. , Warner C. , Catterall W.A.
      J. Biol. Chem.265:14738-14741(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 961-975; 992-1000 AND 1033-1050;PROTEOLYTIC PROCESSING;SUBUNIT
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