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Index > Protein center > CABYR(Gene name) > Human
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  • CABYR (Gene name),
  • Calcium-binding tyrosine phosphorylation-regulated protein (Protein name ),  CABYR_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CABYR(CBP86;FSP2);
    Protein name:
    Calcium-binding tyrosine phosphorylation-regulated protein;
    Alternative:
    Cancer/testis antigen 88(CT88);Calcium-binding protein 86;Fibrousheathin-2(FSP-2);Fibrousheathin II;Testis-specific calcium-binding protein CBP86;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with FSCB (By similarity). Isoform 3 self-associates. Isoform 3 and isoform 5 interact with GSK3B. Isoform 1 does not interact with GSK3B.
    Function:
    May function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium.
    Subcellular Location:
    Isoform 5 Nucleus Cytoplasm Cell projection cilium flagellum According to PubMed:15752768, isoform 1, isoform 3 and isoform 5 are both nuclear and cytoplasmic.
    Protein Attributes:
    Sequence length:
    493
    Sequence:
    50:
    MISSKPRLVV | PYGLKTLLEG | ISRAVLKTNP | SNINQFAAAY | FQELTMYRGN | 
    100:
    TTMDIKDLVK | QFHQIKVEKW | SEGTTPQKKL | ECLKEPGKTS | VESKVPTQME | 
    150:
    KSTDTDEDNV | TRTEYSDKTT | QFPSVYAVPG | TEQTEAVGGL | SSKPATPKTT | 
    200:
    TPPSSPPPTA | VSPEFAYVPA | DPAQLAAQML | GKVSSIHSDQ | SDVLMVDVAT | 
    250:
    SMPVVIKEVP | SSEAAEDVMV | AAPLVCSGKV | LEVQVVNQTS | VHVDLGSQPK | 
    300:
    ENEAEPSTAS | SVPLQDEQEP | PAYDQAPEVT | LQADIEVMST | VHISSVYNDV | 
    350:
    PVTEGVVYIE | QLPEQIVIPF | TDQVACLKEN | EQSKENEQSP | RVSPKSVVEK | 
    400:
    TTSGMSKKSV | ESVKLAQLEE | NAKYSSVYME | AEATALLSDT | SLKGQPEVPA | 
    450:
    QLLDAEGAIK | IGSEKSLHLE | VEITSIVSDN | TGQEESGENS | VPQEMEGKPV | 
    493:
    LSGEAAEAVH | SGTSVKSSSG | PFPPAPEGLT | APEIEPEGES | TAE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    String:
    KEGG:
    MIM:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Calcium-binding tyrosine phosphorylation-regulated protein
    ELISA Kit for Human Calcium-binding tyrosine phosphorylation-regulated protein
    CLIA Kit for Human Calcium-binding tyrosine phosphorylation-regulated protein
    CLIA Kit for Human Calcium-binding tyrosine phosphorylation-regulated protein
    Polyclonal Antibody for Human Calcium-binding tyrosine phosphorylation-regulated protein
    Polyclonal Antibody for Human Calcium-binding tyrosine phosphorylation-regulated protein
    Monoclonal Antibody for Human Calcium-binding tyrosine phosphorylation-regulated protein
    Monoclonal Antibody for Human Calcium-binding tyrosine phosphorylation-regulated protein
    Protein for Human Calcium-binding tyrosine phosphorylation-regulated protein
    Protein for Human Calcium-binding tyrosine phosphorylation-regulated protein

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "CABYR, a novel calcium-binding tyrosine phosphorylation-regulated fibrous sheath protein involved in capacitation."
      Naaby-Hansen S. , Mandal A. , Wolkowicz M.J. , Sen B. , Westbrook V.A. , Shetty J. , Coonrod S.A. , Klotz K.L. , Kim Y.-H. , Bush L.A. , Flickinger C.J. , Herr J.C.
      Dev. Biol.242:236-254(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3; 4; 5 AND 6);PROTEIN SEQUENCE OF 8-23; 28-48; 379-388 AND 394-410;VARIANTS ARG-448 AND ALA-490;CALCIUM-BINDING;PHOSPHORYLATION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
      tissue: Testis.
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Brain.
    3. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      tissue: Ovary.
    5. 6.
      "Characterization of two non-testis-specific CABYR variants that bind to GSK3beta with a proline-rich extensin-like domain."
      Hsu H.-C. , Lee Y.-L. , Cheng T.-S. , Howng S.-L. , Chang L.-K. , Lu P.-J. , Hong Y.-R.
      Biochem. Biophys. Res. Commun.329:1108-1117(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING (ISOFORMS 3 AND 5);SUBUNIT;INTERACTION WITH GSK3B;PHOSPHORYLATION AT THR-151 AND SER-155;MUTAGENESIS OF THR-146; THR-151; SER-154; SER-155 AND THR-159;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    6. 7.
      "Translation and assembly of CABYR coding region B in fibrous sheath and restriction of calcium binding to coding region A."
      Kim Y.-H. , Jha K.N. , Mandal A. , Vanage G. , Farris E. , Snow P.L. , Klotz K. , Naaby-Hansen S. , Flickinger C.J. , Herr J.C.
      Dev. Biol.286:46-56(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CALCIUM-BINDING;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
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