Gene name:
CDH15 (CDH14;CDH3) ;
Protein name:
Cadherin-15 ;
Alternative:
Muscle cadherin (M-cadherin) ;Cadherin-14 ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. M-cadherin is part of the myogenic program and may provide a trigger for terminal muscle differentiation.
Subcellular Location:
Cell membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MDAAFLLVLG | LLAQSLCLSL | GVPGWRRPTT | LYPWRRAPAL | SRVRRAWVIP |
100:
PISVSENHKR | LPYPLVQIKS | DKQQLGSVIY | SIQGPGVDEE | PRGVFSIDKF |
150:
TGKVFLNAML | DREKTDRFRL | RAFALDLGGS | TLEDPTDLEI | VVVDQNDNRP |
200:
AFLQEAFTGR | VLEGAVPGTY | VTRAEATDAD | DPETDNAALR | FSILQQGSPE |
250:
LFSIDELTGE | IRTVQVGLDR | EVVAVYNLTL | QVADMSGDGL | TATASAIITL |
300:
DDINDNAPEF | TRDEFFMEAI | EAVSGVDVGR | LEVEDRDLPG | SPNWVARFTI |
350:
LEGDPDGQFT | IRTDPKTNEG | VLSIVKALDY | ESCEHYELKV | SVQNEAPLQA |
400:
AALRAERGQA | KVRVHVQDTN | EPPVFQENPL | RTSLAEGAPP | GTLVATFSAR |
450:
DPDTEQLQRL | SYSKDYDPED | WLQVDAATGR | IQTQHVLSPA | SPFLKGGWYR |
500:
AIVLAQDDAS | QPRTATGTLS | IEILEVNDHA | PVLAPPPPGS | LCSEPHQGPG |
550:
LLLGATDEDL | PPHGAPFHFQ | LSPRLPELGR | NWSLSQVNVS | HARLRPRHQV |
600:
PEGLHRLSLL | LRDSGQPPQQ | REQPLNVTVC | RCGKDGVCLP | GAAALLAGGT |
650:
GLSLGALVIV | LASALLLLVL | VLLVALRARF | WKQSRGKGLL | HGPQDDLRDN |
700:
VLNYDEQGGG | EEDQDAYDIS | QLRHPTALSL | PLGPPPLRRD | APQGRLHPQP |
750:
PRVLPTSPLD | IADFINDGLE | AADSDPSVPP | YDTALIYDYE | GDGSVAGTLS |
800:
SILSSQGDED | QDYDYLRDWG | PRFARLADMY | GHPCGLEYGA | RWDHQAREGL |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human Cadherin-15
ELISA Kit for Human Cadherin-15
CLIA Kit for Human Cadherin-15
CLIA Kit for Human Cadherin-15
Polyclonal Antibody for Human Cadherin-15
Polyclonal Antibody for Human Cadherin-15
Monoclonal Antibody for Human Cadherin-15
Monoclonal Antibody for Human Cadherin-15
Protein for Human Cadherin-15
Protein for Human Cadherin-15
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Skeletal muscle .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Muscle .
3.
"Alterations in CDH15 and KIRREL3 in patients with mild to severe intellectual disability."
Bhalla K.
,
Luo Y.
,
Buchan T.
,
Beachem M.A.
,
Guzauskas G.F.
,
Ladd S.
,
Bratcher S.J.
,
Schroer R.J.
,
Balsamo J.
,
DuPont B.R.
,
Lilien J.
,
Srivastava A.K.
Am. J. Hum. Genet.83:703-713(2008)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY;CHROMOSOMAL TRANSLOCATION WITH KIRREL3;VARIANTS MRD3 LEU-8; CYS-60; TRP-92 AND VAL-122;MUTAGENESIS OF LYS-103 AND MET-109;CHARACTERIZATION OF VARIANTS MRD3 CYS-60; TRP-92 AND VAL-122