Protein name:
Cadherin-3 ;
Alternative:
Placental cadherin (P-cadherin) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with CDCP1.
Function:
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Subcellular Location:
Cell membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MGLPRGPLAS | LLLLQVCWLQ | CAASEPCRAV | FREAEVTLEA | GGAEQEPGQA |
100:
LGKVFMGCPG | QEPALFSTDN | DDFTVRNGET | VQERRSLKER | NPLKIFPSKR |
150:
ILRRHKRDWV | VAPISVPENG | KGPFPQRLNQ | LKSNKDRDTK | IFYSITGPGA |
200:
DSPPEGVFAV | EKETGWLLLN | KPLDREEIAK | YELFGHAVSE | NGASVEDPMN |
250:
ISIIVTDQND | HKPKFTQDTF | RGSVLEGVLP | GTSVMQVTAT | DEDDAIYTYN |
300:
GVVAYSIHSQ | EPKDPHDLMF | TIHRSTGTIS | VISSGLDREK | VPEYTLTIQA |
350:
TDMDGDGSTT | TAVAVVEILD | ANDNAPMFDP | QKYEAHVPEN | AVGHEVQRLT |
400:
VTDLDAPNSP | AWRATYLIMG | GDDGDHFTIT | THPESNQGIL | TTRKGLDFEA |
450:
KNQHTLYVEV | TNEAPFVLKL | PTSTATIVVH | VEDVNEAPVF | VPPSKVVEVQ |
500:
EGIPTGEPVC | VYTAEDPDKE | NQKISYRILR | DPAGWLAMDP | DSGQVTAVGT |
550:
LDREDEQFVR | NNIYEVMVLA | MDNGSPPTTG | TGTLLLTLID | VNDHGPVPEP |
600:
RQITICNQSP | VRQVLNITDK | DLSPHTSPFQ | AQLTDDSDIY | WTAEVNEEGD |
650:
TVVLSLKKFL | KQDTYDVHLS | LSDHGNKEQL | TVIRATVCDC | HGHVETCPGP |
700:
WKGGFILPVL | GAVLALLFLL | LVLLLLVRKK | RKIKEPLLLP | EDDTRDNVFY |
750:
YGEEGGGEED | QDYDITQLHR | GLEARPEVVL | RNDVAPTIIP | TPMYRPRPAN |
800:
PDEIGNFIIE | NLKAANTDPT | APPYDTLLVF | DYEGSGSDAA | SLSSLTSSAS |
829:
DQDQDYDYLN | EWGSRFKKLA | DMYGGGEDD
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Bovine
Pig
ELISA Kit for Human Cadherin-3
ELISA Kit for Human Cadherin-3
ELISA Kit for Human Cadherin-3
ELISA Kit for Human Cadherin-3
CLIA Kit for Human Cadherin-3
CLIA Kit for Human Cadherin-3
CLIA Kit for Human Cadherin-3
CLIA Kit for Human Cadherin-3
Polyclonal Antibody for Human Cadherin-3
Polyclonal Antibody for Human Cadherin-3
Polyclonal Antibody for Human Cadherin-3
Polyclonal Antibody for Human Cadherin-3
Monoclonal Antibody for Human Cadherin-3
Monoclonal Antibody for Human Cadherin-3
Monoclonal Antibody for Human Cadherin-3
Monoclonal Antibody for Human Cadherin-3
Protein for Human Cadherin-3
Protein for Human Cadherin-3
Protein for Human Cadherin-3
Protein for Human Cadherin-3
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT HIS-563
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Nat. Genet.36:40-45(2004)
[
PubMed ]
[
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT HIS-563
tissue :
Tongue .
3.
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more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT HIS-563
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2);VARIANT MET-237
tissue :
Skin .
tissue :
Testis .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-15
tissue :
Fetal brain .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH CDCP1
8.
"Hypotrichosis with juvenile macular dystrophy is caused by a mutation in CDH3, encoding P-cadherin."
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Nat. Genet.29:134-136(2001)
[
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[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INVOLVEMENT IN HJMD
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH CTNNB1
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
11.
"A missense mutation in CDH3, encoding P-cadherin, causes hypotrichosis with juvenile macular dystrophy."
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J. Invest. Dermatol.119:1210-1213(2002)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT HJMD HIS-503
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT EEM ILE-322;VARIANT HIS-563