Cdh5 ELISA Kit for Mouse(Mus musculus) | EIAab.comCdh5 ELISA Kit for Mouse(Mus musculus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Cdh5(Gene name) > Mouse

Cdh5 (Gene name),

Cadherin-5 (Protein name ), CADH5_MOUSE from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

Cdh5;

Protein name:

Cadherin-5;

Alternative:

Vascular endothelial cadherin(VE-cadherin);

CD:

CD144;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts via cadherin 5 domain with PTPRB. Interacts with TRPC4. Interacts with KRIT1.

Function:

Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.

Subcellular Location:

Cell junction Cell membrane Single-pass type I membrane protein Found at cell-cell boundaries and probably at cell-matrix boundaries. KRIT1 and CDH5 reciprocally regulate their localization to endothelial cell-cell junctions.

Protein Attributes:

Sequence length:

784

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

784:

SDSDIDYDFL | NDWGPRFKML | AELYGSDPQE | ELII

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

STRING:

10090.ENSMUSP00000034339

String:

P55284

Pfam:

PF00028

UniGene:

Mm.21767

KEGG:

mmu:12562

SMR:

P55284

Uniprot:

P55284

FOR

ELISA Kit for Mouse Cadherin-5

Cat.:

E1366h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Mouse Cadherin-5

Cat.:

E1366b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Mouse Cadherin-5

Cat.:

E1366m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Mouse Cadherin-5

Cat.:

E1366c

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Mouse Cadherin-5

Cat.:

E1366p

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse Cadherin-5

Cat.:

U1366c

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse Cadherin-5

Cat.:

U1366h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Mouse Cadherin-5

Cat.:

U1366b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse Cadherin-5

Cat.:

U1366p

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse Cadherin-5

Cat.:

U1366m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Mouse Cadherin-5

Cat.:

P1366Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Cadherin-5

Cat.:

P1366Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Cadherin-5

Protein for Mouse Cadherin-5

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning and expression of murine vascular endothelial-cadherin in early stage development of cardiovascular system."
Breier G. , Breviario F. , Caveda L. , Berthier R. , Schnuerch H. , Gotsch U. , Vestweber D. , Risau W. , Dejana E.
Blood87:630-641(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain capillary.
2.

Breviario F.
Submitted (2003-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION TO 67-70
3.

"In vivo evidence of the critical role of cadherin-5 in murine vascular integrity."
Matsuyoshi N. , Toda K. , Horiguchi Y. , Tanaka T. , Nakagawa S. , Takeichi M. , Imamura S.
Proc. Assoc. Am. Physicians109:362-371(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION
strain: BALB/c.
tissue: Mammary carcinoma.
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6.
tissue: Brain.
5.

"VE-PTP and VE-cadherin ectodomains interact to facilitate regulation of phosphorylation and cell contacts."
Nawroth R. , Poell G. , Ranft A. , Kloep S. , Samulowitz U. , Fachinger G. , Golding M. , Shima D.T. , Deutsch U. , Vestweber D.
EMBO J.21:4885-4895(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PTPRB;PHOSPHORYLATION;DEPHOSPHORYLATION BY PTPRB
6.

Nawroth R. , Poell G. , Ranft A. , Kloep S. , Samulowitz U. , Fachinger G. , Golding M. , Shima D.T. , Deutsch U. , Vestweber D.
EMBO J.24:3158-3158(2005)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
7.

"Impaired vascular development in the yolk sac and allantois in mice lacking RA-GEF-1."
Kanemura H. , Satoh T. , Bilasy S.E. , Ueda S. , Hirashima M. , Kataoka T.
Biochem. Biophys. Res. Commun.387:754-759(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;DEVELOPMENTAL STAGE
8.

"CCM1 regulates vascular-lumen organization by inducing endothelial polarity."
Lampugnani M.G. , Orsenigo F. , Rudini N. , Maddaluno L. , Boulday G. , Chapon F. , Dejana E.
J. Cell Sci.123:1073-1080(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
9.

"SOX7 regulates the expression of VE-cadherin in the haemogenic endothelium at the onset of haematopoietic development."
Costa G. , Mazan A. , Gandillet A. , Pearson S. , Lacaud G. , Kouskoff V.
Development139:1587-1598(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION;DEVELOPMENTAL STAGE
10.

"Distal interactions within the par3-VE-cadherin complex."
Tyler R.C. , Peterson F.C. , Volkman B.F.
Biochemistry49:951-957(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 769-784 IN COMPLEX WITH PARD3;INTERACTION WITH PARD3;MUTAGENESIS OF TYR-774 AND ASP-777

Product Feedback Wall

* Email:
*Comments: