Gene name:
Capn1 (Canp1;Capa1) ;
Protein name:
Calpain-1 catalytic subunit ;
Alternative:
Calpain mu-type ;Calcium-activated neutral proteinase 1 (CANP 1) ;Micromolar-calpain (muCANP) ;Calpain-1 large subunit ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Forms a heterodimer with a small (regulatory) subunit (CAPNS1).
Function:
Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
Subcellular Location:
Cytoplasm
Cell membrane
Translocates to the plasma membrane upon Ca(2+) binding.
Protein Attributes:
50:
MTEELITPVY | CTGVSAQVQK | KRDKELGLGR | HENAIKYLGQ | DYETLRARCL |
100:
QSGVLFQDEA | FPPVSHSLGF | KELGPHSSKT | YGIKWKRPTE | LMSNPQFIVD |
150:
GATRTDICQG | ALGDCWLLAA | IASLTLNETI | LHRVVPYGQS | FQDGYAGIFH |
200:
FQLWQFGEWV | DVVIDDLLPT | KDGKLVFVHS | AQGNEFWSAL | LEKAYAKVNG |
250:
SYEALSGGCT | SEAFEDFTGG | VTEWYDLQKA | PSDLYQIILK | ALERGSLLGC |
300:
SINISDIRDL | EAITFKNLVR | GHAYSVTGAK | QVTYQGQRVN | LIRMRNPWGE |
350:
VEWKGPWSDS | SYEWNKVDPY | EREQLRVKME | DGEFWMSFRD | FIREFTKLEI |
400:
CNLTPDALKS | RTLRNWNTTF | YEGTWRRGST | AGGCRNYPAT | FWVNPQFKIR |
450:
LEEVDDADDY | DNRESGCSFL | LALMQKHRRR | ERRFGRDMET | IGFAVYQVPR |
500:
ELAGQPVHLK | RDFFLANASR | AQSEHFINLR | EVSNRIRLPP | GEYIVVPSTF |
550:
EPNKEGDFLL | RFFSEKKAGT | QELDDQIQAN | LPDEKVLSEE | EIDDNFKTLF |
600:
SKLAGDDMEI | SVKELQTILN | RIISKHKDLR | TNGFSLESCR | SMVNLMDRDG |
650:
NGKLGLVEFN | ILWNRIRNYL | TIFRKFDLDK | SGSMSAYEMR | MAIEAAGFKL |
700:
NKKLHELIIT | RYSEPDLAVD | FDNFVCCLVR | LETMFRFFKL | LDTDLDGVVT |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Pig
Rabbit
Mouse
Bovine
ELISA Kit for Mouse Calpain-1 catalytic subunit
ELISA Kit for Mouse Calpain-1 catalytic subunit
ELISA Kit for Mouse Calpain-1 catalytic subunit
ELISA Kit for Mouse Calpain-1 catalytic subunit
ELISA Kit for Mouse Calpain-1 catalytic subunit
ELISA Kit for Mouse Calpain-1 catalytic subunit
CLIA Kit for Mouse Calpain-1 catalytic subunit
CLIA Kit for Mouse Calpain-1 catalytic subunit
CLIA Kit for Mouse Calpain-1 catalytic subunit
CLIA Kit for Mouse Calpain-1 catalytic subunit
CLIA Kit for Mouse Calpain-1 catalytic subunit
CLIA Kit for Mouse Calpain-1 catalytic subunit
Polyclonal Antibody for Mouse Calpain-1 catalytic subunit
Polyclonal Antibody for Mouse Calpain-1 catalytic subunit
Polyclonal Antibody for Mouse Calpain-1 catalytic subunit
Polyclonal Antibody for Mouse Calpain-1 catalytic subunit
Polyclonal Antibody for Mouse Calpain-1 catalytic subunit
Polyclonal Antibody for Mouse Calpain-1 catalytic subunit
Monoclonal Antibody for Mouse Calpain-1 catalytic subunit
Monoclonal Antibody for Mouse Calpain-1 catalytic subunit
Monoclonal Antibody for Mouse Calpain-1 catalytic subunit
Monoclonal Antibody for Mouse Calpain-1 catalytic subunit
Monoclonal Antibody for Mouse Calpain-1 catalytic subunit
Monoclonal Antibody for Mouse Calpain-1 catalytic subunit
Protein for Mouse Calpain-1 catalytic subunit
Protein for Mouse Calpain-1 catalytic subunit
Protein for Mouse Calpain-1 catalytic subunit
Protein for Mouse Calpain-1 catalytic subunit
Protein for Mouse Calpain-1 catalytic subunit
Protein for Mouse Calpain-1 catalytic subunit
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
CF-1 .
2.
"Cloning and characterization of the cDNA and gene encoding the mouse mu-calpain large subunit protein."
Sahr K.E.
,
Andrabi S.
,
Peters L.L.
,
Chishti A.H.
Submitted (1998-08) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
129 .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
FVB/N .
tissue :
Colon .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Brain .