Protein name:
Calpain-6 ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts (via domain III) with microtubules. Interacts (via domain II) with ARHGEF2 (via the N-terminal zinc finger).
Function:
Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues.
Subcellular Location:
Cytoplasm
perinuclear region
Cytoplasm
cytoskeleton
spindle
Protein Attributes:
50:
MGPPLKLFKN | QKYQELKQEC | MKDGRLFCDP | TFLPENDSLF | FNRLLPGKVV |
100:
WKRPQDISDD | PHLIVGNISN | HQLIQGRLGN | KAMISAFSCL | AVQESHWTKA |
150:
IPNHKDQEWD | PRKPEKYAGI | FHFRFWHFGE | WTEVVIDDLL | PTINGDLVFS |
200:
FSTSMNEFWN | ALLEKAYAKL | LGCYEALDGL | TITDIIMDFT | GTLAEIIDMQ |
250:
KGRYTDLVEE | KYKLFGELYK | TFTKGGLICC | SIESPSQEEQ | EVETDWGLLK |
300:
GYTYTMTDIR | KLRLGERLVE | VFSTEKLYMV | RLRNPLGRQE | WSGPWSEISE |
350:
EWQQLTVTDR | KNLGLVMSDD | GEFWMSLEDF | CHNFHKLNVC | RNVNNPVFGR |
400:
KELESVVGCW | TVDDDPLMNR | SGGCYNNRDT | FLQNPQYIFT | VPEDGHKVIM |
450:
SLQQKDLRTY | RRMGRPDNYI | IGFELFKVEM | NRRFRLHHLY | IQERAGTSTY |
500:
IDTRTVFLSK | YLKKGSYVLV | PTMFQHGRTS | EFLLRIFSEV | PVQLRELTLD |
550:
MPKMSCWNLA | RGYPKVVTQI | TVHSAEGLEK | KYANETVNPY | LIIKCGKEEV |
600:
RSPVQKNTVH | AIFDTQAIFY | RRTTDIPIII | QVWNSRKFCD | QFLGQVTLDA |
641:
DPSDCRDLKS | LYLRKKGGPT | AKVKQGHISF | KVISSDDLTE | L
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Mouse Calpain-6
ELISA Kit for Mouse Calpain-6
ELISA Kit for Mouse Calpain-6
CLIA Kit for Mouse Calpain-6
CLIA Kit for Mouse Calpain-6
CLIA Kit for Mouse Calpain-6
Polyclonal Antibody for Mouse Calpain-6
Polyclonal Antibody for Mouse Calpain-6
Polyclonal Antibody for Mouse Calpain-6
Monoclonal Antibody for Mouse Calpain-6
Monoclonal Antibody for Mouse Calpain-6
Monoclonal Antibody for Mouse Calpain-6
Protein for Mouse Calpain-6
Protein for Mouse Calpain-6
Protein for Mouse Calpain-6
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
BALB/c .
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[
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Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Mammary gland .
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Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DEVELOPMENTAL STAGE;FUNCTION;INTERACTION WITH MICROTUBULE;SUBCELLULAR LOCATION
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INDUCTION;SUBCELLULAR LOCATION
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH ARHGEF2