Gene name:
Capn8 (Cls4;Ncl2) ;
Protein name:
Calpain-8 ;
Alternative:
New calpain 2 (nCL-2) ;Calpain large subunit 4 ;Stomach-specific M-type calpain ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Monomer and homoligomer. Interacts with COPS1/GPS1, COPB1, EYA2, NME2, NME4 and TOMM70A.
Function:
Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta-subunit of coatomer complex.
Subcellular Location:
Cytoplasm
Golgi apparatus
Protein Attributes:
50:
MAALAAGVSK | QRAVAEGLGS | NQNAVKYLGQ | DFETLRKQCL | NSGVLFKDPE |
100:
FPACPSALGY | KDLGPGSPDT | QGIVWKRPTE | LCPNPQFIVG | GATRTDIRQG |
150:
GLGDCWLLAA | IASLTLNEKL | LYRVLPRDQS | FQKDYAGIFH | FQFWQYGEWV |
200:
EVVIDDRLPT | KNGQLLFLHS | EEGNEFWSAL | LEKAYAKLNG | SYEALVGGST |
250:
IEGFEDFTGG | ISEFYDLKKP | PENLYYIIQK | ALRKGSLLGC | SIDVSTAAEA |
300:
EATTRQKLVK | GHAYSVTGVE | EVNFHGRPEK | LIRLRNPWGE | VEWSGAWSDN |
350:
APEWNYIDPR | RKEELDKKAE | DGEFWMSFSD | FLKQYSRLEI | CNLSPDSLSS |
400:
EEIHKWNLVL | FNGRWTRGST | AGGCLNYPGT | YWTNPQFKIH | LDEVDEDQEE |
450:
GTSEPCCTVL | LGLMQKNRRR | QKRIGQGMLS | IGYAVYQIPK | ELESHTDAHL |
500:
GRDFFLGRQP | STCSSTYMNL | REVSSRVRLP | PGQYLVVPST | FEPFKDGDFC |
550:
LRVFSEKKAK | ALEIGDTVSG | HPHEPHPRDM | DEEDEHVRSL | FEEFVGKDSE |
600:
ISANQLKRVL | NEVLSKRTDM | KFDGFNINTC | REMISLLDSD | GTGSLGPMEF |
650:
KTLWLKIRTY | LEIFQEMDHN | HVGTIEAHEM | RTALKKAGFT | LNNQVQQTIA |
700:
MRYACSKLGV | DFNGFVACMI | RLETLFKLFR | LLDKDQNGIV | QLSLAEWLCC |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Mouse
ELISA Kit for Rat Calpain-8
ELISA Kit for Rat Calpain-8
ELISA Kit for Rat Calpain-8
CLIA Kit for Rat Calpain-8
CLIA Kit for Rat Calpain-8
CLIA Kit for Rat Calpain-8
Polyclonal Antibody for Rat Calpain-8
Polyclonal Antibody for Rat Calpain-8
Polyclonal Antibody for Rat Calpain-8
Monoclonal Antibody for Rat Calpain-8
Monoclonal Antibody for Rat Calpain-8
Monoclonal Antibody for Rat Calpain-8
Protein for Rat Calpain-8
Protein for Rat Calpain-8
Protein for Rat Calpain-8
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);SUBCELLULAR LOCATION;TISSUE SPECIFICITY
tissue :
Gastric mucosa .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-17;TISSUE SPECIFICITY
strain :
Sprague-Dawley .