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Index > Protein center > Capn8(Gene name) > Rat
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  • Capn8 (Gene name),
  • Calpain-8 (Protein name ),  CAN8_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Capn8(Cls4;Ncl2);
    Protein name:
    Calpain-8;
    Alternative:
    New calpain 2(nCL-2);Calpain large subunit 4;Stomach-specific M-type calpain;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Monomer and homoligomer. Interacts with COPS1/GPS1, COPB1, EYA2, NME2, NME4 and TOMM70A.
    Function:
    Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta-subunit of coatomer complex.
    Subcellular Location:
    Cytoplasm Golgi apparatus
    Protein Attributes:
    Sequence length:
    703
    Sequence:
    50:
    MAALAAGVSK | QRAVAEGLGS | NQNAVKYLGQ | DFETLRKQCL | NSGVLFKDPE | 
    100:
    FPACPSALGY | KDLGPGSPDT | QGIVWKRPTE | LCPNPQFIVG | GATRTDIRQG | 
    150:
    GLGDCWLLAA | IASLTLNEKL | LYRVLPRDQS | FQKDYAGIFH | FQFWQYGEWV | 
    200:
    EVVIDDRLPT | KNGQLLFLHS | EEGNEFWSAL | LEKAYAKLNG | SYEALVGGST | 
    250:
    IEGFEDFTGG | ISEFYDLKKP | PENLYYIIQK | ALRKGSLLGC | SIDVSTAAEA | 
    300:
    EATTRQKLVK | GHAYSVTGVE | EVNFHGRPEK | LIRLRNPWGE | VEWSGAWSDN | 
    350:
    APEWNYIDPR | RKEELDKKAE | DGEFWMSFSD | FLKQYSRLEI | CNLSPDSLSS | 
    400:
    EEIHKWNLVL | FNGRWTRGST | AGGCLNYPGT | YWTNPQFKIH | LDEVDEDQEE | 
    450:
    GTSEPCCTVL | LGLMQKNRRR | QKRIGQGMLS | IGYAVYQIPK | ELESHTDAHL | 
    500:
    GRDFFLGRQP | STCSSTYMNL | REVSSRVRLP | PGQYLVVPST | FEPFKDGDFC | 
    550:
    LRVFSEKKAK | ALEIGDTVSG | HPHEPHPRDM | DEEDEHVRSL | FEEFVGKDSE | 
    600:
    ISANQLKRVL | NEVLSKRTDM | KFDGFNINTC | REMISLLDSD | GTGSLGPMEF | 
    650:
    KTLWLKIRTY | LEIFQEMDHN | HVGTIEAHEM | RTALKKAGFT | LNNQVQQTIA | 
    700:
    MRYACSKLGV | DFNGFVACMI | RLETLFKLFR | LLDKDQNGIV | QLSLAEWLCC | 
    703:
    VLV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Calpain-8
    ELISA Kit for Rat Calpain-8
    ELISA Kit for Rat Calpain-8
    CLIA Kit for Rat Calpain-8
    CLIA Kit for Rat Calpain-8
    CLIA Kit for Rat Calpain-8
    Polyclonal Antibody for Rat Calpain-8
    Polyclonal Antibody for Rat Calpain-8
    Polyclonal Antibody for Rat Calpain-8
    Monoclonal Antibody for Rat Calpain-8
    Monoclonal Antibody for Rat Calpain-8
    Monoclonal Antibody for Rat Calpain-8
    Protein for Rat Calpain-8
    Protein for Rat Calpain-8
    Protein for Rat Calpain-8

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "A novel tissue-specific calpain species expressed predominantly in the stomach comprises two alternative splicing products with and without Ca(2+)-binding domain."
      Sorimachi H. , Ishiura S. , Suzuki K.
      J. Biol. Chem.268:19476-19482(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);SUBCELLULAR LOCATION;TISSUE SPECIFICITY
      tissue: Gastric mucosa.
    2. 2.
      "Estrogen regulates a tissue-specific calpain in the anterior pituitary."
      Duan W.R. , Ito M. , Lee E.J. , Chien P.-Y. , Jameson J.L.
      Biochem. Biophys. Res. Commun.295:261-266(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-17;TISSUE SPECIFICITY
      strain: Sprague-Dawley.
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