Protein name:
    Macrophage-capping protein ;
    
    Alternative:
    
    Actin-capping protein GCAP39 ;Actin regulatory protein CAP-G ;Myc basic motif homolog 1 ;
    
    
 
    Organism:
        
        
        
        
        
        
    
        Mouse  (Mus musculus).  
    
 
General Annotation
    Function:
    Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA. Uncapping occurs either when Ca(2+) falls or when the concentration of polyphosphoinositide rises, both at low and high Ca(2+).
    
 
    
        
        Subcellular Location:
        
    
     
     
      Nucleus 
      
     
      Cytoplasm 
      
     
      Secreted 
      
     
      Melanosome 
      
    Nuclear GCAP39 redistributes throughout the cytoplasm during mitosis and is excluded from regions containing chromosomes. 
  
    
 
    
    Protein Attributes:
    
    50:
    MYTPIPQSGS |  PFPASVQDPG |  LHIWRVEKLK |  PVPIARESHG |  IFFSGDSYLV |  
    
 
    100:
    LHNGPEEASH |  LHLWIGQQSS |  RDEQGACAVL |  AVHLNTLLGE |  RPVQHREVQG |  
    
 
    150:
    NESDLFMSYF |  PRGLKYYREG |  GVESAFHKTT |  SGARGAAIRK |  LYQVKGKKNI |  
    
 
    200:
    RATERPLSWD |  SFNTGDCFIL |  DLGQNIFAWC |  GGKSNILERN |  KARDLALAIR |  
    
 
    250:
    DSERQGKAQV |  EIITDGEEPA |  EMIQVLGPKP |  ALKEGNPEED |  ITADQTRPNA |  
    
 
    300:
    QAAALYKVSD |  ATGQMNLTKV |  ADSSPFASEL |  LIPDDCFVLD |  NGLCAQIYIW |  
    
 
    350:
    KGRKANEKER |  QAALQVADGF |  ISRMRYSPNT |  QVEILPQGRE |  SPIFKQFFKN |  
    
 
      Vaild Sequence:
    
 
Related Databases
Uniprot:
 
 
    
        
        ELISA Kit
         
        
        CLIA Kit
         
        
        Polyclonal Antibody
         
        
        Monoclonal Antibody
         
        
        Protein
         
        
     
FOR
    
        
        Mouse
         
        
        Human
         
        
        Bovine
         
        
        Rat
         
        
     
    
        ELISA Kit for Mouse Macrophage-capping protein
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
    
    
    
    
 
    
        ELISA Kit for Mouse Macrophage-capping protein
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
    
    
    
    
 
    
        ELISA Kit for Mouse Macrophage-capping protein
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        ELISA Kit for Mouse Macrophage-capping protein
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Mouse Macrophage-capping protein
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Mouse Macrophage-capping protein
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Mouse Macrophage-capping protein
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Mouse Macrophage-capping protein
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Mouse Macrophage-capping protein
        
     
    
    
    
    
   
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Mouse Macrophage-capping protein
        
     
    
    
    
    
   
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Mouse Macrophage-capping protein
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Mouse Macrophage-capping protein
        
     
    
    
    
    
   
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Mouse Macrophage-capping protein
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Mouse Macrophage-capping protein
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Mouse Macrophage-capping protein
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Mouse Macrophage-capping protein
        
     
    
    
    
    
    
    
 
    
        Protein for Mouse Macrophage-capping protein
        
     
    
    
    
    
    
    
 
    
        Protein for Mouse Macrophage-capping protein
        
     
    
    
    
    
    
    
 
    
        Protein for Mouse Macrophage-capping protein
        
     
    
    
    
    
    
    
 
    
        Protein for Mouse Macrophage-capping protein
        
     
    
    
    
    
    
    
 
 
 
 
 
 
 
 
    R&D Technical Data
    
    
    
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    Precision
    
    
    
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    Recovery
    
    
    
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    Linearity
    
    
    
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    References
    
    
        
            
        
            
                1.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [MRNA] 
                    
                    
                    strain :
                    
NIH Swiss .  
             
         
            
        
            
                2.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [MRNA] 
                    
                    
                    tissue :
                    
Kidney .  
             
         
            
        
            
                3.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for PARTIAL PROTEIN SEQUENCE 
                    
                    
                 
             
         
            
        
            
                4.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for SUBCELLULAR LOCATION