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Index > Protein center > Card11(Gene name) > Mouse
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  • Card11 (Gene name),
  • Caspase recruitment domain-containing protein 11 (Protein name ),  CAR11_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Card11;
    Protein name:
    Caspase recruitment domain-containing protein 11;
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Found in a membrane raft complex, at least composed of BCL10, CARD11, DPP4 and IKBKB. CARD11 and BCL10 bind to each other by CARD-CARD interaction. Interacts (via PDZ domain) with DPP4 (via cytoplasmic tail).
    Function:
    Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.
    Subcellular Location:
    Cytoplasm Membrane raft Colocalized with DPP4 in membrane rafts.
    Protein Attributes:
    Sequence length:
    1159
    Sequence:
    50:
    MPGGGPAMDD | YMETLKDEEE | ALWDNVECNR | HMLSRYINPA | KLTPYLRQCK | 
    100:
    VIDEQDEDEV | LNAPMLPSKI | NRAGRLLDIL | HTKGQRGYVV | FLESLEFYYP | 
    150:
    ELYKLVTGKE | PTRRFSTIVV | EEGHEGLTHF | LMNEVIKLQQ | QVKAKDLQRC | 
    200:
    ELLAKSRQLE | DEKKQLSLIR | VELLTFQERY | YKMKEERDSY | NDELVKVKDD | 
    250:
    NYNLAMRYAQ | LSEEKNMAVM | RSRDLQLEID | QLKHRLNKME | EECKLERNQS | 
    300:
    LKLKNDIENR | PRKEQVLELE | RENEMLKTKI | QELQSIIQAG | KRSLPDSDKA | 
    350:
    ILDILEHDRK | EALEDRQELV | NKIYNLQEEV | RQAEELRDKY | LEEKEDLELK | 
    400:
    CSTLGKDCEM | YKHRMNTVML | QLEEVERERD | QAFHSRDEAQ | TQYSQCLIEK | 
    450:
    DKYRKQIREL | EEKNDEMRIE | MVRREACIVN | LESKLRRLSK | DNGSLDQSLP | 
    500:
    RHLPATIISQ | NLGDTSPRTN | GQEADDSSTS | EESPEDSKYF | LPYHPPRRRM | 
    550:
    NLKGIQLQRA | KSPISMKQAS | EFQALMRTVK | GHEEDFTDGS | PSSSRSLPVT | 
    600:
    SSFSKMQPHR | SRSSIMSITA | EPPGNDSIVR | RCKEDAPHRS | TVEEDNDSCG | 
    650:
    FDALDLDDEN | HERYSFGPPS | IHSSSSSHQS | EGLDAYDLEQ | VNLMLRKFSL | 
    700:
    ERPFRPSVTS | GGHVRGTGPL | VQHTTLNGDG | LITQLTLLGG | NARGSFIHSV | 
    750:
    KPGSLAERAG | LREGHQLLLL | EGCIRGERQS | VPLDACTKEE | ARWTIQRCSG | 
    800:
    LITLHYKVNH | EGYRKLLKEM | EDGLITSGDS | FYIRLNLNIS | SQLDACSMSL | 
    850:
    KCDDVVHVLD | TMYQDRHEWL | CARVDPFTDQ | DLDTGTIPSY | SRAQQLLLVK | 
    900:
    LQRLVHRGNR | EEADSAHHTL | RSLRNTLQPE | EMLSTSDPRV | SPRLSRASFF | 
    950:
    FGQLLQFVSR | SENKYKRMNS | NERVRIISGS | PLGSLSRSSL | DATKLLTEKH | 
    1000:
    EELDPENELS | RNLTLIPYSL | VRAFHCERRR | PVLFTPTMLA | KTLVQKLLNS | 
    1050:
    GGAMEFTICK | SDIVTRDEFL | RKQKTETIIY | SREKNPNTFE | CIVPANIEAV | 
    1100:
    AAKNKHCLLE | AGIGCVRDLI | KCKVYPIVLL | IRVSEKNIKR | FRKLLPRPET | 
    1150:
    EEEFLRVCRL | KEKELEALPC | LYATVEAEMW | SSVEELLRVL | KDKIVEEQRK | 
    1159:
    TIWVDEDQL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Caspase recruitment domain-containing protein 11
    ELISA Kit for Mouse Caspase recruitment domain-containing protein 11
    CLIA Kit for Mouse Caspase recruitment domain-containing protein 11
    CLIA Kit for Mouse Caspase recruitment domain-containing protein 11
    Polyclonal Antibody for Mouse Caspase recruitment domain-containing protein 11
    Polyclonal Antibody for Mouse Caspase recruitment domain-containing protein 11
    Monoclonal Antibody for Mouse Caspase recruitment domain-containing protein 11
    Monoclonal Antibody for Mouse Caspase recruitment domain-containing protein 11
    Protein for Mouse Caspase recruitment domain-containing protein 11
    Protein for Mouse Caspase recruitment domain-containing protein 11

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "CARD11 mediates factor-specific activation of NF-kappaB by the T cell receptor complex."
      Pomerantz J.L. , Denny E.M. , Baltimore D.
      EMBO J.21:5184-5194(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Thymus.
    2. 2.
      "Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
      Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Koseki H. , Hiraoka S. , Saga Y. , Kitamura H. , Nakagawa T. , Nagase T. , Ohara O. , Koga H.
      DNA Res.11:127-135(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Thymus.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      strain: 129.
      tissue: Mammary tumor.
    4. 4.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 611-1159
      strain: C57BL/6J.
      tissue: Thymus.
    5. 5.
      "Phosphorylation of the CARMA1 linker controls NF-kappaB activation."
      Sommer K. , Guo B. , Pomerantz J.L. , Bandaranayake A.D. , Moreno-Garcia M.E. , Ovechkina Y.L. , Rawlings D.J.
      Immunity23:561-574(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;PHOSPHORYLATION AT SER-564; SER-649 AND SER-657
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