CARD17 ELISA Kit for Human(Homo sapiens) | EIAab.comCARD17 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > CARD17(Gene name) > Human

CARD17 (Gene name),

Caspase recruitment domain-containing protein 17 (Protein name ), CAR17_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

CARD17(INCA);

Protein name:

Caspase recruitment domain-containing protein 17;

Alternative:

Inhibitory caspase recruitment domain protein;Caspase-1 inhibitor INCA;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with pro-CASP1.

Function:

Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

110

Sequence:

50:

100:

110:

TQDSQIVLPS |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.44102

String:

Q5XLA6

MIM:

609490

SMR:

Q5XLA6

UniGene:

Hs.732627

KEGG:

hsa:440068

Pfam:

PF00619

Uniprot:

Q5XLA6

FOR

ELISA Kit for Human Caspase recruitment domain-containing protein 17

CLIA Kit for Human Caspase recruitment domain-containing protein 17

Polyclonal Antibody for Human Caspase recruitment domain-containing protein 17

Monoclonal Antibody for Human Caspase recruitment domain-containing protein 17

Protein for Human Caspase recruitment domain-containing protein 17

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation."
Lamkanfi M. , Denecker G. , Kalai M. , D'hondt K. , Meeus A. , Declercq W. , Saelens X. , Vandenabeele P.
J. Biol. Chem.279:51729-51738(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;INTERACTION WITH CASP1;INDUCTION;TISSUE SPECIFICITY

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