Protein name:
Caspase recruitment domain-containing protein 9 (hCARD9) ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Self-associates. CARD9 and BCL10 bind to each other by CARD-CARD interaction.
Function:
Activates NF-kappa-B via BCL10.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MSDYENDDEC | WSVLEGFRVT | LTSVIDPSRI | TPYLRQCKVL | NPDDEEQVLS |
100:
DPNLVIRKRK | VGVLLDILQR | TGHKGYVAFL | ESLELYYPQL | YKKVTGKEPA |
150:
RVFSMIIDAS | GESGLTQLLM | TEVMKLQKKV | QDLTALLSSK | DDFIKELRVK |
200:
DSLLRKHQER | VQRLKEECEA | GSRELKRCKE | ENYDLAMRLA | HQSEEKGAAL |
250:
MRNRDLQLEI | DQLKHSLMKA | EDDCKVERKH | TLKLRHAMEQ | RPSQELLWEL |
300:
QQEKALLQAR | VQELEASVQE | GKLDRSSPYI | QVLEEDWRQA | LRDHQEQANT |
350:
IFSLRKDLRQ | GEARRLRCME | EKEMFELQCL | ALRKDSKMYK | DRIEAILLQM |
400:
EEVAIERDQA | IATREELHAQ | HARGLQEKDA | LRKQVRELGE | KADELQLQVF |
450:
QCEAQLLAVE | GRLRRQQLET | LVLSSDLEDG | SPRRSQELSL | PQDLEDTQLS |
500:
DKGCLAGGGS | PKQPFAALHQ | EQVLRNPHDA | GLSSGEPPEK | ERRRLKESFE |
536:
NYRRKRALRK | MQKGWRQGEE | DRENTTGSDN | TDTEGS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
ELISA Kit for Human hCARD9
ELISA Kit for Human hCARD9
CLIA Kit for Human hCARD9
CLIA Kit for Human hCARD9
Polyclonal Antibody for Human hCARD9
Polyclonal Antibody for Human hCARD9
Monoclonal Antibody for Human hCARD9
Monoclonal Antibody for Human hCARD9
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT ASN-12;FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH BCL10
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more...
Nat. Genet.36:40-45(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3);VARIANT ASN-12
tissue :
Retinoblastoma .
tissue :
Synovium .
3.
"DNA sequence and analysis of human chromosome 9."
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.
Mural R.J.
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Istrail S.
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more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue :
Muscle .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-460;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Platelet .
7.
"A homozygous CARD9 mutation in a family with susceptibility to fungal infections."
Glocker E.-O.
,
Hennigs A.
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Nabavi M.
,
Schaeffer A.A.
,
Woellner C.
,
Salzer U.
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Pfeifer D.
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Warnatz K.
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Tahami F.
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Plebani A.
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Hannesschlaeger N.
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Gross O.
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Ruland J.
,
Grimbacher B.
more...
N. Engl. J. Med.361:1727-1735(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INVOLVEMENT IN CANDF2
8.
"Invasive fungal infection and impaired neutrophil killing in human CARD9 deficiency."
Drewniak A.
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Gazendam R.P.
,
Tool A.T.
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van Houdt M.
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Jansen M.H.
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van Hamme J.L.
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Roos D.
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Scalais E.
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de Beaufort C.
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Janssen H.
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van den Berg T.K.
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Kuijpers T.W.
Blood121:2385-2392(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS CANDF2 SER-72 AND PRO-373
9.
"Deep dermatophytosis and inherited CARD9 deficiency."
Lanternier F.
,
Pathan S.
,
Vincent Q.B.
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Liu L.
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Cypowyj S.
,
Prando C.
,
Migaud M.
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Puel A.
more...
N. Engl. J. Med.369:1704-1714(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT CANDF2 CYS-101