CASP4 ELISA Kit for Human(Homo sapiens) | EIAab.comCASP4 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > CASP4(Gene name) > Human

CASP4 (Gene name),

Caspase-4 (Protein name ), CASP4_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CASP4(ICH2);

Protein name:

Caspase-4(CASP-4);

Alternative:

Protease ICH-2;ICE(rel)-II;Protease TX;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a small and a large subunit.

Function:

Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves caspase-1.

Subcellular Location:

Protein Attributes:

Sequence length:

377

Sequence:

50:

100:

150:

200:

250:

300:

350:

377:

ETPRAKAQMP | TIERLSMTRY | FYLFPGN

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P49662

UniGene:

Hs.138378

KEGG:

hsa:837

SMR:

P49662

Pfam:

PF00619

STRING:

9606.ENSP00000388566

MIM:

602664

Uniprot:

P49662

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ELISA Kit for Human CASP-4

Cat.:

E1735h

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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ELISA Kit for Human CASP-4

Cat.:

E1735m

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Human CASP-4

Cat.:

E1735b

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MSDS:

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Packing:

96T

CLIA Kit for Human CASP-4

Cat.:

U1735h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human CASP-4

Cat.:

U1735b

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human CASP-4

Cat.:

U1735m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human CASP-4

Cat.:

P1735Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human CASP-4

Cat.:

P1735Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human CASP-4

Monoclonal Antibody for Human CASP-4

Protein for Human CASP-4

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"A novel human protease similar to the interleukin-1 beta converting enzyme induces apoptosis in transfected cells."
Faucheu C. , Diu A. , Chan A.W.E. , Blanchet A.-M. , Miossec C. , Herve F. , Collard-Dutilleul V. , Gu Y. , Aldape R.A. , Lippke J.A. , Rocher C. , Su M.S.-S. , Livingston D.J. , Hercend T. , Lalanne J.-L.
EMBO J.14:1914-1922(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);MUTAGENESIS OF CYS-258;3D-STRUCTURE MODELING
tissue: Placenta.
2.

"Molecular cloning and pro-apoptotic activity of ICErelII and ICErelIII, members of the ICE/CED-3 family of cysteine proteases."
Munday N.A. , Vaillancourt J.P. , Ali A. , Casano F.J. , Miller D.K. , Molineaux S.M. , Yamin T.-T. , Yu V.L. , Nicholson D.W.
J. Biol. Chem.270:15870-15876(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
3.

"Identification and characterization of ICH-2, a novel member of the interleukin-1 beta-converting enzyme family of cysteine proteases."
Kamens J. , Paskind M. , Hugunin M. , Talanian R.V. , Allen H. , Banach D. , Bump N.J. , Hackett M.C. , Johnston C.G. , Li P. , Mankovich J.A. , Terranova M. , Ghayur T.
J. Biol. Chem.270:15250-15256(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);CHARACTERIZATION
tissue: Thymus.
4.

"Cloning of human ICE homolog Mih1."
Fernandes-Alnemri T. , Litwack G. , Alnemri E.S.
Submitted (1995-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
5.

NIEHS SNPs program
Submitted (2007-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
6.

"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Taylor T.D. , Noguchi H. , Totoki Y. , Toyoda A. , Kuroki Y. , Dewar K. , Lloyd C. , Itoh T. , Takeda T. , Kim D.-W. , She X. , Barlow K.F. , Bloom T. , Bruford E. , Chang J.L. , Cuomo C.A. , Eichler E. , FitzGerald M.G. , more...
Nature440:497-500(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

Mural R.J. , Istrail S. , Sutton G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Testis.
9.

"Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death."
Hitomi J. , Katayama T. , Eguchi Y. , Kudo T. , Taniguchi M. , Koyama Y. , Manabe T. , Yamagishi S. , Bando Y. , Imaizumi K. , Tsujimoto Y. , Tohyama M.
J. Cell Biol.165:347-356(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
10.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-83;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
11.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-83;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
12.

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P. , Lasa M. , Polevoda B. , Gazquez C. , Elosegui-Artola A. , Kim D.S. , De Juan-Pardo E. , Demeyer K. , Hole K. , Larrea E. , Timmerman E. , Prieto J. , Arnesen T. , Sherman F. , Gevaert K. , Aldabe R.
Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.

"Transmembrane protein 214 (TMEM214) mediates endoplasmic reticulum stress-induced caspase 4 enzyme activation and apoptosis."
Li C. , Wei J. , Li Y. , He X. , Zhou Q. , Yan J. , Zhang J. , Liu Y. , Liu Y. , Shu H.B.
J. Biol. Chem.288:17908-17917(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH TMEM214
14.

"The E.coli effector protein NleF is a caspase inhibitor."
Blasche S. , Moertl M. , Steuber H. , Siszler G. , Nisa S. , Schwarz F. , Lavrik I. , Gronewold T.M.A. , Maskos K. , Donnenberg M.S. , Ullmann D. , Uetz P. , Koegl M.
PLoS ONE0:0-0(2013)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH E.COLI NLEF;CATALYTIC ACTIVITY;FUNCTION;ENZYME REGULATION

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