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Index > Protein center > CASP5(Gene name) > Human
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  • CASP5 (Gene name),
  • Caspase-5 (Protein name ),  CASP5_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    CASP5(ICH3);
    Protein name:
    Caspase-5(CASP-5);
    Alternative:
    Protease ICH-3;ICE(rel)-III;Protease TY;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 20 kDa (p20) and a 10 kDa (p10) subunits.
    Function:
    Mediator of programmed cell death (apoptosis).
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    434
    Sequence:
    50:
    MAEDSGKKKR | RKNFEAMFKG | ILQSGLDNFV | INHMLKNNVA | GQTSIQTLVP | 
    100:
    NTDQKSTSVK | KDNHKKKTVK | MLEYLGKDVL | HGVFNYLAKH | DVLTLKEEEK | 
    150:
    KKYYDTKIED | KALILVDSLR | KNRVAHQMFT | QTLLNMDQKI | TSVKPLLQIE | 
    200:
    AGPPESAEST | NILKLCPREE | FLRLCKKNHD | EIYPIKKRED | RRRLALIICN | 
    250:
    TKFDHLPARN | GAHYDIVGMK | RLLQGLGYTV | VDEKNLTARD | MESVLRAFAA | 
    300:
    RPEHKSSDST | FLVLMSHGIL | EGICGTAHKK | KKPDVLLYDT | IFQIFNNRNC | 
    350:
    LSLKDKPKVI | IVQACRGEKH | GELWVRDSPA | SLALISSQSS | ENLEADSVCK | 
    400:
    IHEEKDFIAF | CSSTPHNVSW | RDRTRGSIFI | TELITCFQKY | SCCCHLMEIF | 
    434:
    RKVQKSFEVP | QAKAQMPTIE | RATLTRDFYL | FPGN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    MIM:
    String:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human CASP-5
    CLIA Kit for Human CASP-5
    Polyclonal Antibody for Human CASP-5
    Monoclonal Antibody for Human CASP-5
    Protein for Human CASP-5

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Identification of a novel exon encoding the amino-terminus of the predominant caspase-5 variants."
      Eckhart L. , Kittel C. , Gawlas S. , Gruber F. , Mildner M. , Jilma B. , Tschachler E.
      Biochem. Biophys. Res. Commun.348:682-688(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3; 4 AND 5);ALTERNATIVE SPLICING (ISOFORM 6);VARIANTS ALA-106 AND VAL-334;INDUCTION BY LPS
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANT ALA-106
      tissue: Colon.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "Molecular cloning and pro-apoptotic activity of ICErelII and ICErelIII, members of the ICE/CED-3 family of cysteine proteases."
      Munday N.A. , Vaillancourt J.P. , Ali A. , Casano F.J. , Miller D.K. , Molineaux S.M. , Yamin T.-T. , Yu V.L. , Nicholson D.W.
      J. Biol. Chem.270:15870-15876(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 6-434 (ISOFORM 1);VARIANTS ALA-106 AND VAL-334
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 9-434 (ISOFORM 1);VARIANTS LEU-29; ALA-106; HIS-168; LEU-217 AND VAL-334
      tissue: Colon.
    6. 6.
      "Identification of a cysteine protease closely related to interleukin-1 beta-converting enzyme."
      Faucheu C. , Blanchet A.-M. , Collard-Dutilleul V. , Lalanne J.-L. , Diu-Hercend A.
      Eur. J. Biochem.236:207-213(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 37-434;VARIANT ALA-106
      tissue: Placenta.
      tissue: Spleen.
    7. 7.
      NIEHS SNPs program
      Submitted (2006-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS ASN-19; LEU-29; ARG-75; ALA-106; HIS-168; LEU-217; HIS-298; VAL-334; LYS-353 AND GLN-382
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT ALA-106
    9. 9.
      "The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing."
      Papin S. , Cuenin S. , Agostini L. , Martinon F. , Werner S. , Beer H.D. , Grutter C. , Grutter M. , Tschopp J.
      Cell Death Differ.14:1457-1466(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MEFV
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