CASP6 ELISA Kit for Human(Homo sapiens) | EIAab.comCASP6 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > CASP6(Gene name) > Human

CASP6 (Gene name),

Caspase-6 (Protein name ), CASP6_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CASP6(MCH2);

Protein name:

Caspase-6(CASP-6);

Alternative:

Apoptotic protease Mch-2;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 18 kDa (p18) and a 11 kDa (p11) subunit.

Function:

Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

293

Sequence:

50:

100:

150:

200:

250:

293:

LVNRKVSQRR | VDFCKDPSAI | GKKQVPCFAS | MLTKKLHFFP | KSN

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P55212

Pfam:

PF00656

STRING:

9606.ENSP00000265164

MIM:

601532

String:

P55212

UniGene:

Hs.654616

KEGG:

hsa:839

Uniprot:

P55212

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ELISA Kit for Human CASP-6

Cat.:

E9634h

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Human CASP-6

Cat.:

E9634m

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MSDS:

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Packing:

96T

ELISA Kit for Human CASP-6

Cat.:

E9634b

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MSDS:

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Packing:

96T

ELISA Kit for Human CASP-6

Cat.:

E9634r

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96T

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CLIA Kit for Human CASP-6

Cat.:

U9634r

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Manual:

Looking for manual.

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Packing:

96T

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CLIA Kit for Human CASP-6

Cat.:

U9634h

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MSDS:

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Packing:

96T

CLIA Kit for Human CASP-6

Cat.:

U9634b

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human CASP-6

Cat.:

U9634m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human CASP-6

Cat.:

P9634Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human CASP-6

Cat.:

P9634Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human CASP-6

Cat.:

P9634Rb-r

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human CASP-6

Protein for Human CASP-6

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family."
Fernandes-Alnemri T. , Litwack G. , Alnemri E.S.
Cancer Res.55:2737-2742(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS ALPHA AND BETA)
tissue: T-cell.
2.

NIEHS SNPs program
Submitted (2003-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT SER-182
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM ALPHA)
tissue: Lung.
4.

"The Ced-3/interleukin 1beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32."
Srinivasula S.M. , Fernandes-Alnemri T. , Zangrilli J. , Robertson N. , Armstrong R.C. , Wang L. , Trapani J.A. , Tomaselli K.J. , Litwack G. , Alnemri E.S.
J. Biol. Chem.271:27099-27106(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEOLYTIC PROCESSING
tissue: Lymphocyte.
5.

"Dual role of BRUCE as an antiapoptotic IAP and a chimeric E2/E3 ubiquitin ligase."
Bartke T. , Pohl C. , Pyrowolakis G. , Jentsch S.
Mol. Cell14:801-811(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH BIRC6/BRUCE
6.

"Regulation of caspase-6 and FLIP by the AMPK family member ARK5."
Suzuki A. , Kusakai G. , Kishimoto A. , Shimojo Y. , Miyamoto S. , Ogura T. , Ochiai A. , Esumi H.
Oncogene23:7067-7075(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION;PHOSPHORYLATION AT SER-257;MUTAGENESIS OF SER-257
7.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

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