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Index > Protein center > Casr(Gene name) > Mouse
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  • Casr (Gene name),
  • Extracellular calcium-sensing receptor (Protein name ),  CASR_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Casr(Gprc2a);
    Protein name:
    Extracellular calcium-sensing receptor(CaSR);
    Alternative:
    Parathyroid cell calcium-sensing receptor(PCaR1);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with VCP and RNF19A. Interacts with ARRB1.
    Function:
    Senses changes in the extracellular concentration of calcium ions. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    1079
    Sequence:
    50:
    MAWFGYCLAL | LALTWHSSAY | GPDQRAQKKG | DIILGGLFPI | HFGVAAKDQD | 
    100:
    LKSRPESVEC | IRYNFRGFRW | LQAMIFAIEE | INSSPALLPN | MTLGYRIFDT | 
    150:
    CNTVSKALEA | TLSFVAQNKI | DSLNLDEFCN | CSEHIPSTIA | VVGATGSGVS | 
    200:
    TAVANLLGLF | YIPQVSYASS | SRLLSNKNQF | KSFLRTIPND | EHQATAMADI | 
    250:
    IEYFRWNWVG | TIAADDDYGR | PGIEKFREEA | EERDICIDFS | ELISQYSDEE | 
    300:
    EIQQVVEVIQ | NSTAKVIVVF | SSGPDLEPLI | KEIVRRNITG | RIWLASEAWA | 
    350:
    SSSLIAMPEY | FHVVGGTIGF | GLKAGQIPGF | REFLQKVHPR | KSVHNGFAKE | 
    400:
    FWEETFNCHL | QDGAKGPLPV | DTFVRSHEEG | GNRLLNSSTA | FRPLCTGDEN | 
    450:
    INSVETPYMG | YEHLRISYNV | YLAVYSIAHA | LQDIYTCLPG | RGLFTNGSCA | 
    500:
    DIKKVEAWQV | LKHLRHLNFT | NNMGEQVTFD | ECGDLVGNYS | IINWHLSPED | 
    550:
    GSIVFKEVGY | YNVYAKKGER | LFINEGKILW | SGFSREVPFS | NCSRDCQAGT | 
    600:
    RKGIIEGEPT | CCFECVECPD | GEYSGETDAS | ACDKCPDDFW | SNENYTSCIA | 
    650:
    KEIEFLAWTE | PFGIALTLFA | VLGIFLTAFV | LGVFIKFRNT | PIVKATNREL | 
    700:
    SYLLLFSLLC | CFSSSLFFIG | EPQDWTCRLR | QPAFGISFVL | CISCILVKTN | 
    750:
    RVLLVFEAKI | PTSFHRKWWG | LNLQFLLVFL | CTFMQIVICI | IWLYTAPPSS | 
    800:
    YRNHELEDEI | IFITCHEGSL | MALGSLIGYT | CLLAAICFFF | AFKSRKLPEN | 
    850:
    FNEAKFITFS | MLIFFIVWIS | FIPAYASTYG | KFVSAVEVIA | ILAASFGLLA | 
    900:
    CIFFNKVYII | LFKPSRNTIE | EVRSSTAAHA | FKVAARATLR | RPNISRKRSS | 
    950:
    SLGGSTGSNP | SSSISSKSNS | EDRFPQPERQ | KQQQPLALTQ | QEQQQQPLTL | 
    1000:
    QPQQQQQPQQ | PRCKQKVIFG | SGTVTFSLSF | DEPQKNAMAH | RNSMRQNSLE | 
    1050:
    AQKSNDTLNR | HQALLPLQCA | EADSEMTIQE | TGLQGPMVGD | HQPEIESPDE | 
    1079:
    MSPALVVSTS | RSFVISGGGS | SVTENILHS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    Pfam:
    UniGene:
    KEGG:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse CaSR
    Cat.:
    E1510b
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse CaSR
    Cat.:
    E1510m
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse CaSR
    Cat.:
    E1510h
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Mouse CaSR
    MSDS:
    Please sign in first.
    ELISA Kit for Mouse CaSR
    Cat.:
    E1510r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse CaSR
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse CaSR
    Cat.:
    U1510b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse CaSR
    Cat.:
    U1510h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse CaSR
    Cat.:
    U1510m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse CaSR
    Cat.:
    U1510r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse CaSR
    Cat.:
    P1510Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse CaSR
    Polyclonal Antibody for Mouse CaSR
    Cat.:
    P1510Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse CaSR
    Cat.:
    P1510Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse CaSR
    Monoclonal Antibody for Mouse CaSR
    Monoclonal Antibody for Mouse CaSR
    Monoclonal Antibody for Mouse CaSR
    Monoclonal Antibody for Mouse CaSR
    Monoclonal Antibody for Mouse CaSR
    Protein for Mouse CaSR
    Protein for Mouse CaSR
    Protein for Mouse CaSR
    Protein for Mouse CaSR
    Protein for Mouse CaSR

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The calcium sensing receptor and its alternatively spliced form in murine epidermal differentiation."
      Oda Y. , Tu C.-L. , Chang W. , Crumrine D. , Koemueves L. , Mauro T. , Elias P.M. , Bikle D.D.
      J. Biol. Chem.275:1183-1190(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];ALTERNATIVE SPLICING;TISSUE SPECIFICITY
      strain: C57BL/6.
      tissue: Kidney.
    2. 2.
      "Sensing of extracellular cations in CasR-deficient osteoblasts. Evidence for a novel cation-sensing mechanism."
      Pi M. , Garner S.C. , Flannery P. , Spurney R.F. , Quarles L.D.
      J. Biol. Chem.275:3256-3263(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A);TISSUE SPECIFICITY
      strain: Black Swiss X 129/SVJ.
      tissue: Kidney.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "Expression and signal transduction of calcium-sensing receptors in cartilage and bone."
      Chang W. , Tu C. , Chen T.-H. , Komuves L. , Oda Y. , Pratt S.A. , Miller S. , Shoback D.
      Endocrinology140:5883-5893(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 256-600 (ISOFORM A);TISSUE SPECIFICITY
      tissue: Epiphyseal cartilage.
    6. 6.
      Hildenbrand J. , Ammon H.P.T. , Wahl M.A.
      Submitted (1998-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 507-582 (ISOFORM A)
      strain: NMRI.
      tissue: Brain.
    7. 7.
      Moawad T.I. , Riccardi D.
      Submitted (1999-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 562-814
      tissue: Kidney.
    8. 8.
      "A distinct cation-sensing mechanism in MC3T3-E1 osteoblasts functionally related to the calcium receptor."
      Quarles L.D. , Hartle J.E. II , Siddhanti S.R. , Guo R. , Hinson T.K.
      J. Bone Miner. Res.12:393-402(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 646-799;TISSUE SPECIFICITY
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