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Index > Protein center > CTSL1(Gene name) > Human
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  • CTSL1 (Gene name),
  • Cathepsin L1 (Protein name ),  CATL1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    CTSL1(CTSL);
    Protein name:
    Cathepsin L1;
    Alternative:
    Major excreted protein(MEP);Major excreted protein(MEP);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Dimer of a heavy and a light chain linked by disulfide bonds.
    Function:
    Important for the overall degradation of proteins in lysosomes.
    Subcellular Location:
    Lysosome
    Protein Attributes:
    Sequence length:
    333
    Sequence:
    50:
    MNPTLILAAF | CLGIASATLT | FDHSLEAQWT | KWKAMHNRLY | GMNEEGWRRA | 
    100:
    VWEKNMKMIE | LHNQEYREGK | HSFTMAMNAF | GDMTSEEFRQ | VMNGFQNRKP | 
    150:
    RKGKVFQEPL | FYEAPRSVDW | REKGYVTPVK | NQGQCGSCWA | FSATGALEGQ | 
    200:
    MFRKTGRLIS | LSEQNLVDCS | GPQGNEGCNG | GLMDYAFQYV | QDNGGLDSEE | 
    250:
    SYPYEATEES | CKYNPKYSVA | NDTGFVDIPK | QEKALMKAVA | TVGPISVAID | 
    300:
    AGHESFLFYK | EGIYFEPDCS | SEDMDHGVLV | VGYGFESTES | DNNKYWLVKN | 
    333:
    SWGEEWGMGG | YVKMAKDRRN | HCGIASAASY | PTV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    Pfam:
    MIM:
    UniGene:
    String:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Cathepsin L1
    Cat.:
    E0306h
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Cathepsin L1
    Cat.:
    E0306c
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Cathepsin L1
    Cat.:
    E0306m
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Cathepsin L1
    Cat.:
    E0306b
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Cathepsin L1
    Cat.:
    E0306r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Cathepsin L1
    Cat.:
    E0306p
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    MSDS:
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    96T
    ELISA Kit for Human Cathepsin L1
    Cat.:
    E0306d
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Cathepsin L1
    Cat.:
    U0306r
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Cathepsin L1
    Cat.:
    U0306m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Cathepsin L1
    Cat.:
    U0306d
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Cathepsin L1
    Cat.:
    U0306b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Cathepsin L1
    Cat.:
    U0306c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Cathepsin L1
    Cat.:
    U0306p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Cathepsin L1
    Cat.:
    U0306h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Cathepsin L1
    Polyclonal Antibody for Human Cathepsin L1
    Polyclonal Antibody for Human Cathepsin L1
    Polyclonal Antibody for Human Cathepsin L1
    Cat.:
    P0306Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Cathepsin L1
    Cat.:
    P0306Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Cathepsin L1
    Cat.:
    P0306Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Cathepsin L1
    Monoclonal Antibody for Human Cathepsin L1
    Monoclonal Antibody for Human Cathepsin L1
    Monoclonal Antibody for Human Cathepsin L1
    Monoclonal Antibody for Human Cathepsin L1
    Monoclonal Antibody for Human Cathepsin L1
    Monoclonal Antibody for Human Cathepsin L1
    Monoclonal Antibody for Human Cathepsin L1
    Protein for Human Cathepsin L1
    Protein for Human Cathepsin L1
    Protein for Human Cathepsin L1
    Protein for Human Cathepsin L1
    Protein for Human Cathepsin L1
    Protein for Human Cathepsin L1
    Protein for Human Cathepsin L1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Isolation and sequence of a cDNA for human pro-(cathepsin L)."
      Gal S. , Gottesman M.M.
      Biochem. J.253:303-306(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Complete nucleotide and deduced amino acid sequences of human and murine preprocathepsin L. An abundant transcript induced by transformation of fibroblasts."
      Joseph L.J. , Chang L.C. , Stamenkovich D. , Sukhatme V.P.
      J. Clin. Invest.81:1621-1629(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Colon endothelium.
    5. 5.
      "DNA sequence and analysis of human chromosome 9."
      Humphray S.J. , Oliver K. , Hunt A.R. , Plumb R.W. , Loveland J.E. , Howe K.L. , Andrews T.D. , Searle S. , Hunt S.E. , Scott C.E. , Jones M.C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Ashwell R.I.S. , Babbage A.K. , Babbage S. , Bagguley C.L. , more...
      Nature429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Prostate.
    7. 7.
      "Amino acid sequences of the human kidney cathepsins H and L."
      Ritonja A. , Popovic T. , Kotnik M. , Machleidt W. , Turk V.
      FEBS Lett.228:341-345(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 114-288 AND 292-333
    8. 8.
      "The major ras induced protein in NIH3T3 cells is cathepsin L."
      Joseph L.J. , Lapid S. , Sukhatme V.P.
      Nucleic Acids Res.15:3186-3186(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 113-154
    9. 9.
      "The N-terminal amino acid sequences of the heavy and light chains of human cathepsin L. Relationship to a cDNA clone for a major cysteine proteinase from a mouse macrophage cell line."
      Mason R.W. , Walker J.E. , Northrop F.D.
      Biochem. J.240:373-377(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 114-154 AND 292-333
    10. 10.
      "Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry."
      Zhang H. , Li X.-J. , Martin D.B. , Aebersold R.
      Nat. Biotechnol.21:660-666(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-221
    11. 11.
      "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
      Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
      J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-221
      tissue: Plasma.
    12. 12.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-221
      tissue: Liver.
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    14. 14.
      "Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment."
      Coulombe R. , Grochulski P. , Sivaraman J. , Menard R. , Mort J.S. , Cygler M.
      EMBO J.15:5492-5503(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 18-333
    15. 15.
      "The crystal structure of human cathepsin L complexed with E-64."
      Fujishima A. , Imai Y. , Nomura T. , Fujisawa Y. , Yamamoto Y. , Sugarawa T.
      FEBS Lett.407:47-50(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 114-333
    16. 16.
      Cygler M. , Coulombe R.
      Submitted (1999-08) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) OF 18-333
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