Protein name:
Carboxypeptidase B2 ;
Alternative:
Plasma carboxypeptidase B (pCPB) ;Carboxypeptidase U (CPU) ;Thrombin-activable fibrinolysis inhibitor (TAFI) ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin.
Subcellular Location:
Secreted
Protein Attributes:
50:
MKLCSLAVLV | PIVLFCEQHV | FAFQSGQVLA | ALPRTSRQVQ | VLQNLTTTYE |
100:
IVLWQPVTAD | LIVKKKQVHF | FVNASDVDNV | KAHLNVSGIP | CSVLLADVED |
150:
LIQQQISNDT | VSPRASASYY | EQYHSLNEIY | SWIEFITERH | PDMLTKIHIG |
200:
SSFEKYPLYV | LKVSGKEQAA | KNAIWIDCGI | HAREWISPAF | CLWFIGHITQ |
250:
FYGIIGQYTN | LLRLVDFYVM | PVVNVDGYDY | SWKKNRMWRK | NRSFYANNHC |
300:
IGTDLNRNFA | SKHWCEEGAS | SSSCSETYCG | LYPESEPEVK | AVASFLRRNI |
350:
NQIKAYISMH | SYSQHIVFPY | SYTRSKSKDH | EELSLVASEA | VRAIEKISKN |
400:
TRYTHGHGSE | TLYLAPGGGD | DWIYDLGIKY | SFTIELRDTG | TYGFLLPERY |
423:
IKPTCREAFA | AVSKIAWHVI | RNV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Bovine
ELISA Kit for Human Carboxypeptidase B2
ELISA Kit for Human Carboxypeptidase B2
ELISA Kit for Human Carboxypeptidase B2
ELISA Kit for Human Carboxypeptidase B2
CLIA Kit for Human Carboxypeptidase B2
CLIA Kit for Human Carboxypeptidase B2
CLIA Kit for Human Carboxypeptidase B2
CLIA Kit for Human Carboxypeptidase B2
Polyclonal Antibody for Human Carboxypeptidase B2
Polyclonal Antibody for Human Carboxypeptidase B2
Polyclonal Antibody for Human Carboxypeptidase B2
Polyclonal Antibody for Human Carboxypeptidase B2
Monoclonal Antibody for Human Carboxypeptidase B2
Monoclonal Antibody for Human Carboxypeptidase B2
Monoclonal Antibody for Human Carboxypeptidase B2
Monoclonal Antibody for Human Carboxypeptidase B2
Protein for Human Carboxypeptidase B2
Protein for Human Carboxypeptidase B2
Protein for Human Carboxypeptidase B2
Protein for Human Carboxypeptidase B2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PARTIAL PROTEIN SEQUENCE;INTERACTION WITH PLASMINOGEN;VARIANTS THR-169 AND THR-347
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Liver .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANTS THR-169 AND THR-347
tissue :
Liver .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT THR-347
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT THR-347
tissue :
Skeletal muscle .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;CATALYTIC ACTIVITY
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-44; ASN-73 AND ASN-108
tissue :
Plasma .
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION AT ASN-44; ASN-73; ASN-85; ASN-108 AND ASN-241;DISULFIDE BONDS
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-108
tissue :
Liver .
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION AT ASN-108;STRUCTURE OF CARBOHYDRATES;IDENTIFICATION BY MASS SPECTROMETRY
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 24-423 ALONE AND IN COMPLEX WITH INHIBITOR;GLYCOSYLATION AT ASN-44; ASN-73; ASN-85 AND ASN-108;ACTIVE SITE;ZINC-BINDING SITES;ENZYME REGULATION;DISULFIDE BONDS
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 115-423 IN COMPLEX WITH INHIBITOR;DISULFIDE BONDS