Protein name:
Cytosolic carboxypeptidase 6 ;
Alternative:
ATP/GTP-binding protein-like 4 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with MYLK.
Function:
Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5.
Subcellular Location:
Cytoplasm
cytosol
Protein Attributes:
50:
MAERSQTAPE | AGNDTGNEDA | IGGNVNKYIV | LPNGYSGQPK | KGHLTFDACF |
100:
ESGNLGRVEQ | VSDFEYDLFI | RPDTCNPRFR | VWFNFTVENV | KELQRVIFNI |
150:
VNFSKTKSLY | RDGMAPMVKS | TSRPKWQRLP | PKNVYYYRCP | DHRKNYVMSF |
200:
AFCFDREDDI | YQFAYCYPYT | YTRFQHYLDS | LQKKNMDYFF | REQLGQSVQQ |
250:
RQLDLLTITS | PENLREGSEK | KVIFITGRVH | PGETPSSFVC | QGIIDFLVSQ |
300:
HPIARVLREH | LVFKIAPMLN | PDGVYLGNYR | CSLMGFDLNR | HWLDPSPWAH |
350:
PTLHGVKQLI | IKMYNDPKTS | LEFYIDIHAH | STMMNGFMYG | NIFEDEERFQ |
400:
RQSIFPKLLC | QNAEDFSYTS | TSFNRDAVKA | GTGRRFLGGL | LDHSSYCYTL |
450:
EVSFYSYIIG | GTTAAVPYTE | EAYMKLGRNV | ARTFLDYYRL | NSLVEKIAVP |
500:
MPRLRSKEER | RLGWEHPSCL | RAEQPLEVLG | IPMCSGKALN | EHLGNDIQWH |
540:
LDCGSSTLPL | GLISCSPSSS | ASWNDMAMSN | SILLPDHSFH |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Mouse Cytosolic carboxypeptidase 6
ELISA Kit for Mouse Cytosolic carboxypeptidase 6
CLIA Kit for Mouse Cytosolic carboxypeptidase 6
CLIA Kit for Mouse Cytosolic carboxypeptidase 6
Polyclonal Antibody for Mouse Cytosolic carboxypeptidase 6
Polyclonal Antibody for Mouse Cytosolic carboxypeptidase 6
Monoclonal Antibody for Mouse Cytosolic carboxypeptidase 6
Monoclonal Antibody for Mouse Cytosolic carboxypeptidase 6
Protein for Mouse Cytosolic carboxypeptidase 6
Protein for Mouse Cytosolic carboxypeptidase 6
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);FUNCTION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION
strain :
C57BL/Ks .
2.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
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PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
3.
"A family of protein-deglutamylating enzymes associated with neurodegeneration."
Rogowski K.
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van Dijk J.
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Magiera M.M.
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Bosc C.
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Deloulme J.C.
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Bosson A.
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Peris L.
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Cell143:564-578(2010)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;TISSUE SPECIFICITY;INTERACTION WITH MYLK;MUTAGENESIS OF HIS-230 AND GLU-233
4.
"The cytosolic carboxypeptidases CCP2 and CCP3 catalyze posttranslational removal of acidic amino acids."
Tort O.
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Tanco S.
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Rocha C.
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Bieche I.
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Seixas C.
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Mol. Biol. Cell25:3017-3027(2014)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;TISSUE SPECIFICITY