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Index > Protein center > Cbx2(Gene name) > Mouse
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  • Cbx2 (Gene name),
  • Chromobox protein homolog 2 (Protein name ),  CBX2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Cbx2(M33);
    Protein name:
    Chromobox protein homolog 2;
    Alternative:
    Modifier 3 protein;M33;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Component of a PRC1-like complex (By similarity). Interacts with RING1.
    Function:
    Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
    Subcellular Location:
    Nucleus speckle
    Protein Attributes:
    Sequence length:
    519
    Sequence:
    50:
    MEELSSVGEQ | VFAAECILSK | RLRKGKLEYL | VKWRGWSSKH | NSWEPEENIL | 
    100:
    DPRLLLAFQK | KEHEKEVQNR | KRGKRPRGRP | RKHTVTSSCS | RRSKLKEPDA | 
    150:
    PSKSKSSSSS | SSSTSSSSSS | DEEEDDSDLD | SKRGPRGRET | HPVPQKKAQI | 
    200:
    LVAKPELKDP | IRKKRGRKPL | PPEQKAARRP | VSLAKVLKTT | RKDLGTSAAK | 
    250:
    LPPPLSAPVA | GLAALKAHTK | EACGGPSTMA | TPENLASLMK | GMAGSPSRGG | 
    300:
    IWQSSIVHYM | NRMSQSQVQA | ASRLALKAQA | TNKCGLGLDL | KVRTQKGGEL | 
    350:
    GGSPAGGKVP | KAPGGGAAEQ | QRGNHSGSPG | AQLAPTQELS | LQVLDLQSVK | 
    400:
    NGVPGVGLLA | RHAPAKAIPA | TNPATGKGPG | SGPTGANMTN | APTDNNKGEK | 
    450:
    LTCKATALPA | PSVKRDTVKS | VAASGGQEGH | TAPGEGRKPP | ALSELSTGEE | 
    500:
    NSSSDSDPDS | TSLPSAAQNL | SVAIQTSQDW | KPTRSLIEHV | FVTDVTANLI | 
    519:
    TVTVKESPTS | VGFFNLRHY
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    KEGG:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Chromobox protein homolog 2
    ELISA Kit for Mouse Chromobox protein homolog 2
    CLIA Kit for Mouse Chromobox protein homolog 2
    CLIA Kit for Mouse Chromobox protein homolog 2
    Polyclonal Antibody for Mouse Chromobox protein homolog 2
    Polyclonal Antibody for Mouse Chromobox protein homolog 2
    Monoclonal Antibody for Mouse Chromobox protein homolog 2
    Monoclonal Antibody for Mouse Chromobox protein homolog 2
    Protein for Mouse Chromobox protein homolog 2
    Protein for Mouse Chromobox protein homolog 2

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "The mouse has a Polycomb-like chromobox gene."
      Pearce J.J.H. , Singh P.B. , Gaunt S.J.
      Development114:921-930(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C57BL/6.
      tissue: Embryo.
    2. 2.
      "Ring1A is a transcriptional repressor that interacts with the Polycomb-M33 protein and is expressed at rhombomere boundaries in the mouse hindbrain."
      Schoorlemmer J. , Marcos-Gutierrez C. , Were F. , Martinez R. , Garcia E. , Satijn D.P.E. , Otte A.P. , Vidal M.
      EMBO J.16:5930-5942(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH RING1;DEVELOPMENTAL STAGE;SUBCELLULAR LOCATION
      tissue: Embryo.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Liver.
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