Protein name:
E3 SUMO-protein ligase CBX4 ;
Alternative:
Polycomb 2 homolog (Pc2;mPc2) ;Chromobox protein homolog 4 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Component of a PRC1-like complex. Interacts with SUV39H1 and HIPK2 (By similarity). Interacts with histone H3-K9Me3. Interacts with CSNK2B.
Function:
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MELPAVGEHV | FAVESIEKKR | IRKGRVEYLV | KWRGWSPKYN | TWEPEENILD |
100:
PRLLIAFQNR | ERQEQLMGYR | KRGPKPKPLV | VQVPTFARRS | NVLTGLQDSS |
150:
ADNRAKLELG | TQGKGQGHQY | ELNSKKHHQY | QPHSKERSGK | PPPPGKSGKY |
200:
YYQLNSKKHH | PYQPDPKMYD | LQYQGGHKEA | PSPTCPDLGT | KSHPPDKWAH |
250:
GAAAKGYLGA | VKPLGGGAGA | PGKGSEKGPP | NGMTPAPKEA | VTGNGIGGKM |
300:
KIVKNKNKNG | RIVIVMSKYM | ENGMQAVKIK | SGEAAEGEAR | SPSHKKRAAE |
350:
ERHPQGDRTF | KKAAGASEEK | KAEVPCKRRE | EEALVSGDAQ | PQDLGSRKLS |
400:
PTKEAFGEQP | LQLTTKPDLL | AWDPARSSHP | PAHHHHHHHH | HHHHHTVGLN |
450:
LSHARKRCLS | ETHGEREPCK | KRLTARSIST | PTCLGGSPVS | EHPANVSPTA |
500:
ASLPQPEVIL | LDSDLDEPID | LRCVKMRSDA | GEPPSTLQVK | PEAPAVAAVV |
550:
APAPASEKPP | AEAQEEPVEP | LSEFKPFFGN | IIITDVTANC | LTVTFKEYVT |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Mouse E3 SUMO-protein ligase CBX4
ELISA Kit for Mouse E3 SUMO-protein ligase CBX4
CLIA Kit for Mouse E3 SUMO-protein ligase CBX4
CLIA Kit for Mouse E3 SUMO-protein ligase CBX4
Polyclonal Antibody for Mouse E3 SUMO-protein ligase CBX4
Polyclonal Antibody for Mouse E3 SUMO-protein ligase CBX4
Monoclonal Antibody for Mouse E3 SUMO-protein ligase CBX4
Monoclonal Antibody for Mouse E3 SUMO-protein ligase CBX4
Protein for Mouse E3 SUMO-protein ligase CBX4
Protein for Mouse E3 SUMO-protein ligase CBX4
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH H3-K9ME3
4.
"Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation."
Fanis P.
,
Gillemans N.
,
Aghajanirefah A.
,
Pourfarzad F.
,
Demmers J.
,
Esteghamat F.
,
Vadlamudi R.K.
,
Grosveld F.
,
Philipsen S.
,
van Dijk T.B.
Mol. Cell. Proteomics11:1263-1273(2012)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH CHTOP