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Index > Protein center > Cbx4(Gene name) > Mouse
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  • Cbx4 (Gene name),
  • E3 SUMO-protein ligase CBX4 (Protein name ),  CBX4_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Cbx4(Pc2);
    Protein name:
    E3 SUMO-protein ligase CBX4;
    Alternative:
    Polycomb 2 homolog(Pc2;mPc2);Chromobox protein homolog 4;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Component of a PRC1-like complex. Interacts with SUV39H1 and HIPK2 (By similarity). Interacts with histone H3-K9Me3. Interacts with CSNK2B.
    Function:
    Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    551
    Sequence:
    50:
    MELPAVGEHV | FAVESIEKKR | IRKGRVEYLV | KWRGWSPKYN | TWEPEENILD | 
    100:
    PRLLIAFQNR | ERQEQLMGYR | KRGPKPKPLV | VQVPTFARRS | NVLTGLQDSS | 
    150:
    ADNRAKLELG | TQGKGQGHQY | ELNSKKHHQY | QPHSKERSGK | PPPPGKSGKY | 
    200:
    YYQLNSKKHH | PYQPDPKMYD | LQYQGGHKEA | PSPTCPDLGT | KSHPPDKWAH | 
    250:
    GAAAKGYLGA | VKPLGGGAGA | PGKGSEKGPP | NGMTPAPKEA | VTGNGIGGKM | 
    300:
    KIVKNKNKNG | RIVIVMSKYM | ENGMQAVKIK | SGEAAEGEAR | SPSHKKRAAE | 
    350:
    ERHPQGDRTF | KKAAGASEEK | KAEVPCKRRE | EEALVSGDAQ | PQDLGSRKLS | 
    400:
    PTKEAFGEQP | LQLTTKPDLL | AWDPARSSHP | PAHHHHHHHH | HHHHHTVGLN | 
    450:
    LSHARKRCLS | ETHGEREPCK | KRLTARSIST | PTCLGGSPVS | EHPANVSPTA | 
    500:
    ASLPQPEVIL | LDSDLDEPID | LRCVKMRSDA | GEPPSTLQVK | PEAPAVAAVV | 
    550:
    APAPASEKPP | AEAQEEPVEP | LSEFKPFFGN | IIITDVTANC | LTVTFKEYVT | 
    551:
    V
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    KEGG:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse E3 SUMO-protein ligase CBX4
    ELISA Kit for Mouse E3 SUMO-protein ligase CBX4
    CLIA Kit for Mouse E3 SUMO-protein ligase CBX4
    CLIA Kit for Mouse E3 SUMO-protein ligase CBX4
    Polyclonal Antibody for Mouse E3 SUMO-protein ligase CBX4
    Polyclonal Antibody for Mouse E3 SUMO-protein ligase CBX4
    Monoclonal Antibody for Mouse E3 SUMO-protein ligase CBX4
    Monoclonal Antibody for Mouse E3 SUMO-protein ligase CBX4
    Protein for Mouse E3 SUMO-protein ligase CBX4
    Protein for Mouse E3 SUMO-protein ligase CBX4

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "MPc2, a new murine homolog of the Drosophila polycomb protein is a member of the mouse polycomb transcriptional repressor complex."
      Alkema M.J. , Jacobs J. , Voncken J.W. , Jenkins N.A. , Copeland N.G. , Satijn D.P.E. , Otte A.P. , Berns A. , van Lohuizen M.
      J. Mol. Biol.273:993-1003(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
    3. 3.
      "Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatin."
      Bernstein E. , Duncan E.M. , Masui O. , Gil J. , Heard E. , Allis C.D.
      Mol. Cell. Biol.26:2560-2569(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH H3-K9ME3
    4. 4.
      "Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation."
      Fanis P. , Gillemans N. , Aghajanirefah A. , Pourfarzad F. , Demmers J. , Esteghamat F. , Vadlamudi R.K. , Grosveld F. , Philipsen S. , van Dijk T.B.
      Mol. Cell. Proteomics11:1263-1273(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CHTOP
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