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Index > Protein center > Ccl21b(Gene name) > Mouse
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  • Ccl21b (Gene name),
  • C-C motif chemokine 21b (Protein name ),  CC21B_MOUSE from NCBI database.
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  • General Annotation
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  • Gene name:
    Ccl21b(Scya21;Scya21b);
    Protein name:
    C-C motif chemokine 21b;
    Alternative:
    Beta-chemokine exodus-2;6Ckine;Thymus-derived chemotactic agent 4(TCA4);Small-inducible cytokine A21b;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Binds to CCR7 and to CXCR3.
    Function:
    Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Potent mesangial cell chemoattractant. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    133
    Sequence:
    50:
    MAQMMTLSLL | SLVLALCIPW | TQGSDGGGQD | CCLKYSQKKI | PYSIVRGYRK | 
    100:
    QEPSLGCPIP | AILFLPRKHS | KPELCANPEE | GWVQNLMRRL | DQPPAPGKQS | 
    133:
    PGCRKNRGTS | KSGKKGKGSK | GCKRTEQTQP | SRG
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse C-C motif chemokine 21b
    CLIA Kit for Mouse C-C motif chemokine 21b
    Polyclonal Antibody for Mouse C-C motif chemokine 21b
    Monoclonal Antibody for Mouse C-C motif chemokine 21b
    Protein for Mouse C-C motif chemokine 21b

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Isolation and characterization of Exodus-2, a novel C-C chemokine with a unique 37-amino acid carboxyl-terminal extension."
      Hromas R. , Kim C.H. , Klemsz M. , Krathwohl M. , Fife K. , Cooper S. , Schnizlein-Bick C. , Broxmeyer H.E.
      J. Immunol.159:2554-2558(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Fetus.
    2. 2.
      "The reduced expression of 6Ckine in the plt mouse results from the deletion of one of two 6Ckine genes."
      Vassileva G. , Soto H. , Zlotnik A. , Nakano H. , Kakiuchi T. , Hedrick J.A. , Lira S.A.
      J. Exp. Med.190:1183-1188(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: 129/SvJ.
      tissue: Embryonic stem cell.
    3. 3.
      "Gene duplications at the chemokine locus on mouse chromosome 4: multiple strain-specific haplotypes and the deletion of secondary lymphoid-organ chemokine and EBI-1 ligand chemokine genes in the plt mutation."
      Nakano H. , Gunn M.D.
      J. Immunol.166:361-369(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: 129/Ola.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    5. 5.
      "A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes."
      Gunn M.D. , Tangemann K. , Tam C. , Cyster J.G. , Rosen S.D. , Williams L.T.
      Proc. Natl. Acad. Sci. U.S.A.95:258-263(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
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