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Index > Protein center > CCL22(Gene name) > Human
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  • CCL22 (Gene name),
  • C-C motif chemokine 22 (Protein name ),  CCL22_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    CCL22(A-152E5.1;MDC;SCYA22);
    Protein name:
    C-C motif chemokine 22;
    Alternative:
    MDC(1-69);CC chemokine STCP-1;Small-inducible cytokine A22;Macrophage-derived chemokine;Stimulated T-cell chemotactic protein 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    93
    Sequence:
    50:
    MDRLQTALLV | VLVLLAVALQ | ATEAGPYGAN | MEDSVCCRDY | VRYRLPLRVV | 
    93:
    KHFYWTSDSC | PRPGVVLLTF | RDKEICADPR | VPWVKMILNK | LSQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    UniGene:
    MIM:
    KEGG:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human C-C motif chemokine 22
    Cat.:
    E0091m
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human C-C motif chemokine 22
    Cat.:
    E0091h
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Human C-C motif chemokine 22
    Cat.:
    U0091m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human C-C motif chemokine 22
    Cat.:
    U0091h
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human C-C motif chemokine 22
    Cat.:
    P0091Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human C-C motif chemokine 22
    Cat.:
    P0091Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human C-C motif chemokine 22
    Monoclonal Antibody for Human C-C motif chemokine 22
    Protein for Human C-C motif chemokine 22
    Protein for Human C-C motif chemokine 22

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular cloning and functional characterization of a novel CC chemokine, stimulated T cell chemotactic protein (STCP-1) that specifically acts on activated T lymphocytes."
      Chang M.-S. , McNinch J. , Elias C. III , Manthey C.L. , Grosshans D. , Meng T. , Boone T. , Andrew D.P.
      J. Biol. Chem.272:25229-25237(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT ALA-2
      tissue: Macrophage.
    2. 2.
      "Human macrophage-derived chemokine (MDC), a novel chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells."
      Godiska R. , Chantry D. , Raport C.J. , Sozzani S. , Allavena P. , Leviten D. , Mantovani A. , Gray P.W.
      J. Exp. Med.185:1595-1604(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 25-35;VARIANT ALA-2
      tissue: Macrophage.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ALA-2
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Peripheral blood.
    5. 5.
      "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q."
      Loftus B.J. , Kim U.-J. , Sneddon V.P. , Kalush F. , Brandon R. , Fuhrmann J. , Mason T. , Crosby M.L. , Barnstead M. , Cronin L. , Mays A.D. , Cao Y. , Xu R.X. , Kang H.-L. , Mitchell S. , Eichler E.E. , Harris P.C. , Venter J.C. , more...
      Genomics60:295-308(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT ALA-2
    6. 6.
      "The sequence and analysis of duplication-rich human chromosome 16."
      Martin J. , Han C. , Gordon L.A. , Terry A. , Prabhakar S. , She X. , Xie G. , Hellsten U. , Chan Y.M. , Altherr M. , Couronne O. , Aerts A. , Bajorek E. , Black S. , Blumer H. , Branscomb E. , Brown N.C. , Bruno W.J. , more...
      Nature432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT ALA-2
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ALA-2
      tissue: Pancreas.
      tissue: Spleen.
    9. 9.
      "Macrophage-derived chemokine is a functional ligand for the CC chemokine receptor 4."
      Imai T. , Chantry D. , Raport C.J. , Wood C.L. , Nishimura M. , Godiska R. , Yoshie O. , Gray P.W.
      J. Biol. Chem.273:1764-1768(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: RECEPTOR INTERACTION
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;PROTEOLYTIC PROCESSING OF N-TERMINUS;IDENTIFICATION OF MDC(3-69); MDC(5-69) AND MDC(7-69)
      tissue: Dendritic cell.
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