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Index > Protein center > Ccnl2(Gene name) > Mouse
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  • Ccnl2 (Gene name),
  • Cyclin-L2 (Protein name ),  CCNL2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Ccnl2(MNCb-5160;Ania6b);
    Protein name:
    Cyclin-L2;
    Alternative:
    Paneth cell-enhanced expression protein(PCEE);Cyclin Ania-6b;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with CDK11A, CDK11B, CDK12, CDK13, SFRS2, SFRS7 and POLR2A, the hyperphosphorylated C-terminal domain (CTD) of RNA polymerase II.
    Function:
    Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Also modulates the expression of critical apoptotic factor, leading to cell apoptosis.
    Subcellular Location:
    Nucleus speckle
    Protein Attributes:
    Sequence length:
    518
    Sequence:
    50:
    MAAAAAGAAG | LMAPASAACS | SGSAGAAPGS | QGVLIGDRLY | SGVLITLENC | 
    100:
    LLPDDKLRFT | PSMSSGLDVD | TETGLRVVGC | ELIQAAGILL | RLPQVAMATG | 
    150:
    QVLFQRFFYT | KSFVKHSMEH | VSMACVHLAS | KIEEAPRRIR | DVINVFHRLR | 
    200:
    HLREKKKPVP | LVLDQEYVNL | KNQIIKAERR | VLKELGFCVH | VKHPHKIIVM | 
    250:
    YLQVLECERN | QHLVQTAWNY | MNDSLRTDVF | VRFQPESIAC | ACIYLAARTL | 
    300:
    EIPLPNRPHW | FLLFGATEEE | IQEICFKILQ | LYTRKKVDLT | HLESEVEKRK | 
    350:
    HAIEEAKARA | KGLLPGTAPG | LDSAAGFSPA | PKLESPKEGK | GGKPSPPSGK | 
    400:
    SAKRKMEGPK | KAQGHSPVNG | LLKGQESRSQ | SRSREQSYSR | SPSRSASPKR | 
    450:
    RKSDSGSTSG | GSKSQSRSRS | RSDSPPRQVH | RGAPYKGSEV | RGSRKSKDCK | 
    500:
    YLTQKPHKSR | SRSSSRSRSR | SRERTDNSGK | YKKKSHYYRD | QRRERSRSYE | 
    518:
    RTGHRYERDH | PGHSRHRR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    KEGG:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Cyclin-L2
    ELISA Kit for Mouse Cyclin-L2
    ELISA Kit for Mouse Cyclin-L2
    CLIA Kit for Mouse Cyclin-L2
    CLIA Kit for Mouse Cyclin-L2
    CLIA Kit for Mouse Cyclin-L2
    Polyclonal Antibody for Mouse Cyclin-L2
    Polyclonal Antibody for Mouse Cyclin-L2
    Polyclonal Antibody for Mouse Cyclin-L2
    Monoclonal Antibody for Mouse Cyclin-L2
    Monoclonal Antibody for Mouse Cyclin-L2
    Monoclonal Antibody for Mouse Cyclin-L2
    Protein for Mouse Cyclin-L2
    Protein for Mouse Cyclin-L2
    Protein for Mouse Cyclin-L2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Dopamine and glutamate induce distinct striatal splice forms of Ania-6, an RNA polymerase II-associated cyclin."
      Berke J.D. , Sgambato V. , Zhu P.-P. , Lavoie B. , Vincent M. , Krause M. , Hyman S.E.
      Neuron32:277-287(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      strain: C57BL/6.
    2. 2.
      "Cyclin L2, a novel RNA polymerase II-associated cyclin, is involved in pre-mRNA splicing and induces apoptosis of human hepatocellular carcinoma cells."
      Yang L. , Li N. , Wang C. , Yu Y. , Yuan L. , Zhang M. , Cao X.
      J. Biol. Chem.279:11639-11648(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      strain: C57BL/6J.
    3. 3.
      "Isolation of full-length cDNA clones from mouse brain cDNA library made by oligo-capping method."
      Osada N. , Kusuda J. , Tanuma R. , Ito A. , Hirata M. , Sugano S. , Hashimoto K.
      Submitted (2000-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: C57BL/6.
      tissue: Brain.
    4. 4.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3)
      strain: C57BL/6J.
      strain: NOD.
      tissue: Head.
      tissue: Pancreas.
      tissue: Skin.
      tissue: Spleen.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    6. 6.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      strain: FVB/N.
      tissue: Brain.
      tissue: Mammary gland.
    8. 8.
      "Patterns of gene expression along the crypt-villus axis in mouse jejunal epithelium."
      Cheng H. , Bjerknes M.
      Anat. Rec.244:78-94(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 321-518
      strain: BALB/c.
      tissue: Jejunal epithelium.
    9. 9.
      "CDK13/CDC2L5 interacts with L-type cyclins and regulates alternative splicing."
      Chen H.H. , Wong Y.H. , Geneviere A.M. , Fann M.J.
      Biochem. Biophys. Res. Commun.354:735-740(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION CDK13
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