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Index > Protein center > CCR1(Gene name) > Human
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  • CCR1 (Gene name),
  • C-C chemokine receptor type 1 (Protein name ),  CCR1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    CCR1(CMKBR1;CMKR1;SCYAR1);
    Protein name:
    C-C chemokine receptor type 1(C-C CKR-1;CC-CKR-1;CCR-1;CCR1);
    Alternative:
    LD78 receptor;HM145;RANTES-R;Macrophage inflammatory protein 1-alpha receptor(MIP-1alpha-R);
    CD:
    CD191;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Function:
    Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    355
    Sequence:
    50:
    METPNTTEDY | DTTTEFDYGD | ATPCQKVNER | AFGAQLLPPL | YSLVFVIGLV | 
    100:
    GNILVVLVLV | QYKRLKNMTS | IYLLNLAISD | LLFLFTLPFW | IDYKLKDDWV | 
    150:
    FGDAMCKILS | GFYYTGLYSE | IFFIILLTID | RYLAIVHAVF | ALRARTVTFG | 
    200:
    VITSIIIWAL | AILASMPGLY | FSKTQWEFTH | HTCSLHFPHE | SLREWKLFQA | 
    250:
    LKLNLFGLVL | PLLVMIICYT | GIIKILLRRP | NEKKSKAVRL | IFVIMIIFFL | 
    300:
    FWTPYNLTIL | ISVFQDFLFT | HECEQSRHLD | LAVQVTEVIA | YTHCCVNPVI | 
    350:
    YAFVGERFRK | YLRQLFHRRV | AVHLVKWLPF | LSVDRLERVS | STSPSTGEHE | 
    355:
    LSAGF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    UniGene:
    MIM:
    Pfam:
    KEGG:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human C-C CKR-1
    Cat.:
    E1534h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human C-C CKR-1
    Cat.:
    E1534m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human C-C CKR-1
    Cat.:
    U1534h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human C-C CKR-1
    Cat.:
    U1534m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human C-C CKR-1
    Cat.:
    P1534Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human C-C CKR-1
    Cat.:
    P1534Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human C-C CKR-1
    Monoclonal Antibody for Human C-C CKR-1
    Protein for Human C-C CKR-1
    Protein for Human C-C CKR-1

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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor."
      Neote K. , Digregorio D. , Mak J.Y. , Horuk R. , Schall T.J.
      Cell72:415-425(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Structure and functional expression of the human macrophage inflammatory protein 1 alpha/RANTES receptor."
      Gao J.-L. , Kuhns D. , Tiffany H.L. , McDermott D. , Li X. , Francke U. , Murphy P.M.
      J. Exp. Med.177:1421-1427(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Molecular cloning of cDNAs encoding a LD78 receptor and putative leukocyte chemotactic peptide receptors."
      Nomura H. , Nielsen B.W. , Matsushima K.
      Int. Immunol.5:1239-1249(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Monocyte.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Blood.
    5. 5.
      "Human LZIP binds to CCR1 and differentially affects the chemotactic activities of CCR1-dependent chemokines."
      Ko J. , Jang S.W. , Kim Y.S. , Kim I.S. , Sung H.J. , Kim H.-H. , Park J.Y. , Lee Y.H. , Kim J. , Na D.S.
      FASEB J.18:890-892(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CREB3
    6. 6.
      "Human LZIP induces monocyte CC chemokine receptor 2 expression leading to enhancement of monocyte chemoattractant protein 1/CCL2-induced cell migration."
      Sung H.J. , Kim Y.S. , Kang H. , Ko J.
      Exp. Mol. Med.40:332-338(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INDUCTION
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