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Index > Protein center > Ccr5(Gene name) > Rat
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  • Ccr5 (Gene name),
  • C-C chemokine receptor type 5 (Protein name ),  CCR5_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Ccr5(Cmkbr5);
    Protein name:
    C-C chemokine receptor type 5(C-C CKR-5;CC-CKR-5;CCR-5);
    Alternative:
    MIP-1 alpha receptor;
    CD:
    CD195;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with PRAF2. Efficient ligand binding to CCL3/MIP-1alpha and CCL4/MIP-1beta requires sulfation, O-glycosylation and sialic acid modifications. Glycosylation on Ser-6 is required for efficient binding of CCL4. Interacts with ADRBK1. Interacts with ARRB1 and ARRB2.
    Function:
    Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    354
    Sequence:
    50:
    MDFQGSIPTY | IYDIDYSMSA | PCQKVNVKQI | AAQLLPPLYS | LVFIFGFVGN | 
    100:
    MMVFLILISC | KKLKSMTDIY | LFNLAISDLL | FLLTLPFWAH | YAANEWVFGN | 
    150:
    IMCKLFTGIY | HIGYFGGIFF | IILLTIDRYL | AIVHAVFAIK | ARTVNFGVIT | 
    200:
    SVVTWVVAVF | VSLPEIIFMR | SQKEGSHYTC | SPHFLHIQYR | FWKHFQTLKM | 
    250:
    VILSLILPLL | VMVICYSGIL | NTLFRCRNEK | KRHRAVRLIF | AIMIVYFLFW | 
    300:
    TPYNIVLLLT | TFQEYFGLNN | CSSSNRLDQA | MQVTETLGMT | HCCLNPVIYA | 
    350:
    FVGEKFRNYL | SVFFRKHIVK | RFCKHCSIFQ | QVNPDRVSSV | YTRSTGEQEV | 
    354:
    STGL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat C-C CKR-5
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    E2055h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Rat C-C CKR-5
    Cat.:
    E2055m
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat C-C CKR-5
    MSDS:
    Please sign in first.
    ELISA Kit for Rat C-C CKR-5
    Cat.:
    E2055d
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Rat C-C CKR-5
    Cat.:
    E2055r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat C-C CKR-5
    Cat.:
    E2055b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat C-C CKR-5
    Cat.:
    U2055r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat C-C CKR-5
    Cat.:
    U2055d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat C-C CKR-5
    Cat.:
    U2055h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat C-C CKR-5
    MSDS:
    Please sign in first.
    CLIA Kit for Rat C-C CKR-5
    Cat.:
    U2055b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat C-C CKR-5
    Cat.:
    U2055m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat C-C CKR-5
    Polyclonal Antibody for Rat C-C CKR-5
    Cat.:
    P2055Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat C-C CKR-5
    Cat.:
    P2055Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat C-C CKR-5
    Cat.:
    P2055Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat C-C CKR-5
    Polyclonal Antibody for Rat C-C CKR-5
    Monoclonal Antibody for Rat C-C CKR-5
    Monoclonal Antibody for Rat C-C CKR-5
    Monoclonal Antibody for Rat C-C CKR-5
    Monoclonal Antibody for Rat C-C CKR-5
    Monoclonal Antibody for Rat C-C CKR-5
    Monoclonal Antibody for Rat C-C CKR-5
    Protein for Rat C-C CKR-5
    Protein for Rat C-C CKR-5
    Protein for Rat C-C CKR-5
    Protein for Rat C-C CKR-5
    Protein for Rat C-C CKR-5
    Protein for Rat C-C CKR-5

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    References
    1. 1.
      "Cloning of rat HIV-1-chemokine coreceptor CKR5 from microglia and upregulation of its mRNA in ischemic and endotoxinemic rat brain."
      Spleiss O. , Gourmala N. , Boddeke H.W.G.M. , Sauter A. , Fiebich B.L. , Berger M. , Gebicke-Haerter P.J.
      J. Neurosci. Res.53:16-28(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Wistar.
      tissue: Brain.
    2. 2.
      "Chemokine receptor expression in cultured glia and rat experimental allergic encephalomyelitis."
      Jiang Y. , Salafranca M.N. , Adhikari S. , Xia Y. , Feng L. , Sonntag M.K. , deFiebre C.M. , Pennell N.A. , Streit W.J. , Harrison J.K.
      J. Neuroimmunol.86:1-12(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: Sprague-Dawley.
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