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Index > Protein center > CCR8(Gene name) > Human
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  • CCR8 (Gene name),
  • C-C chemokine receptor type 8 (Protein name ),  CCR8_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    CCR8(CKRL1;CMKBR8;CMKBRL2);
    Protein name:
    C-C chemokine receptor type 8(C-C CKR-8;CC-CKR-8;CCR-8);
    Alternative:
    CMKBRL2;CC chemokine receptor CHEMR1;GPR-CY6(GPRCY6);Chemokine receptor-like 1(CKR-L1);TER1;
    CD:
    CDw198;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    355
    Sequence:
    50:
    MDYTLDLSVT | TVTDYYYPDI | FSSPCDAELI | QTNGKLLLAV | FYCLLFVFSL | 
    100:
    LGNSLVILVL | VVCKKLRSIT | DVYLLNLALS | DLLFVFSFPF | QTYYLLDQWV | 
    150:
    FGTVMCKVVS | GFYYIGFYSS | MFFITLMSVD | RYLAVVHAVY | ALKVRTIRMG | 
    200:
    TTLCLAVWLT | AIMATIPLLV | FYQVASEDGV | LQCYSFYNQQ | TLKWKIFTNF | 
    250:
    KMNILGLLIP | FTIFMFCYIK | ILHQLKRCQN | HNKTKAIRLV | LIVVIASLLF | 
    300:
    WVPFNVVLFL | TSLHSMHILD | GCSISQQLTY | ATHVTEIISF | THCCVNPVIY | 
    350:
    AFVGEKFKKH | LSEIFQKSCS | QIFNYLGRQM | PRESCEKSSS | CQQHSSRSSS | 
    355:
    VDYIL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    MIM:
    SMR:
    UniGene:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human C-C CKR-8
    Cat.:
    E8691m
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human C-C CKR-8
    Cat.:
    E8691h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human C-C CKR-8
    Cat.:
    U8691h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human C-C CKR-8
    Cat.:
    U8691m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human C-C CKR-8
    Cat.:
    P8691Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human C-C CKR-8
    Cat.:
    P8691Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human C-C CKR-8
    Monoclonal Antibody for Human C-C CKR-8
    Protein for Human C-C CKR-8
    Protein for Human C-C CKR-8

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Molecular cloning and RNA expression of two new human chemokine receptor-like genes."
      Zaballos A. , Varona R. , Gutierrez J. , Lind P. , Marquez G.
      Biochem. Biophys. Res. Commun.227:846-853(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      "Molecular cloning and chromosomal mapping of a novel human gene, ChemR1, expressed in T lymphocytes and polymorphonuclear cells and encoding a putative chemokine receptor."
      Samson M. , Stordeur P. , Labbe O. , Soularue P. , Vassart G. , Parmentier M.
      Eur. J. Immunol.26:3021-3028(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Identification of CCR8: a human monocyte and thymus receptor for the CC chemokine I-309."
      Tiffany H.L. , Lautens L.L. , Gao J.-L. , Pease J. , Locati M. , Combadiere C. , Modi W. , Bonner T.I. , Murphy P.M.
      J. Exp. Med.186:165-170(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1);FUNCTION AS A RECEPTOR FOR CCL1
      tissue: Thymus.
    4. 4.
      "Molecular cloning of TER1, a chemokine receptor-like gene expressed by lymphoid tissues."
      Napolitano M. , Zingoni A. , Bernardini G. , Spinetti G. , Nista A. , Storlazzi C.T. , Rocchi M. , Santoni A.
      J. Immunol.157:2759-2763(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    5. 5.
      "Molecular cloning of a human novel C-C chemokine receptor."
      Nakajima T. , Yoshida R. , Harada S.
      Submitted (1997-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    6. 6.
      "Genomic organization and evolution of the CX3CR1/CCR8 chemokine receptor locus."
      DeVries M.E. , Cao H. , Wang J. , Xu L. , Kelvin A.A. , Ran L. , Chau L.A. , Madrenas J. , Hegele R.A. , Kelvin D.J.
      J. Biol. Chem.278:11985-11994(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT GLY-27
    7. 7.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    8. 8.
      "The DNA sequence, annotation and analysis of human chromosome 3."
      Muzny D.M. , Scherer S.E. , Kaul R. , Wang J. , Yu J. , Sudbrak R. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , more...
      Nature440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    10. 10.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
    11. 11.
      "Identification of the CC chemokines TARC and macrophage inflammatory protein-1 beta as novel functional ligands for the CCR8 receptor."
      Bernardini G. , Hedrick J. , Sozzani S. , Luini W. , Spinetti G. , Weiss M. , Menon S. , Zlotnik A. , Mantovani A. , Santoni A. , Napolitano M.
      Eur. J. Immunol.28:582-588(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    12. 12.
      "Identification of CCR8 as the specific receptor for the human beta-chemokine I-309: cloning and molecular characterization of murine CCR8 as the receptor for TCA-3."
      Goya I. , Gutierrez J. , Varona R. , Kremer L. , Zaballos A. , Marquez G.
      J. Immunol.160:1975-1981(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS A RECEPTOR FOR CCL1
    13. 13.
      "The assignment of chemokine-chemokine receptor pairs: TARC and MIP-1 beta are not ligands for human CC-chemokine receptor 8."
      Garlisi C.G. , Xiao H. , Tian F. , Hedrick J.A. , Billah M.M. , Egan R.W. , Umland S.P.
      Eur. J. Immunol.29:3210-3215(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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