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Index > Protein center > Cd14(Gene name) > Mouse
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  • Cd14 (Gene name),
  • Monocyte differentiation antigen CD14 (Protein name ),  CD14_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    Cd14;
    Protein name:
    Monocyte differentiation antigen CD14;
    Alternative:
    Myeloid cell-specific leucine-rich glycoprotein;
    CD:
    CD14;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Belongs to the lipopolysaccharide (LPS) receptor, a multi-protein complex containing at least CD14, MD-2 and TLR4.
    Function:
    Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
    Subcellular Location:
    Cell membrane Lipid-anchor GPI-anchor
    Protein Attributes:
    Sequence length:
    366
    Sequence:
    50:
    MERVLGLLLL | LLVHASPAPP | EPCELDEESC | SCNFSDPKPD | WSSAFNCLGA | 
    100:
    ADVELYGGGR | SLEYLLKRVD | TEADLGQFTD | IIKSLSLKRL | TVRAARIPSR | 
    150:
    ILFGALRVLG | ISGLQELTLE | NLEVTGTAPP | PLLEATGPDL | NILNLRNVSW | 
    200:
    ATRDAWLAEL | QQWLKPGLKV | LSIAQAHSLN | FSCEQVRVFP | ALSTLDLSDN | 
    250:
    PELGERGLIS | ALCPLKFPTL | QVLALRNAGM | ETPSGVCSAL | AAARVQLQGL | 
    300:
    DLSHNSLRDA | AGAPSCDWPS | QLNSLNLSFT | GLKQVPKGLP | AKLSVLDLSY | 
    350:
    NRLDRNPSPD | ELPQVGNLSL | KGNPFLDSES | HSEKFNSGVV | TAGAPSSQAV | 
    366:
    ALSGTLALLL | GDRLFV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Monocyte differentiation antigen CD14
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    ELISA Kit for Mouse Monocyte differentiation antigen CD14
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    E0685r
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    ELISA Kit for Mouse Monocyte differentiation antigen CD14
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    ELISA Kit for Mouse Monocyte differentiation antigen CD14
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    ELISA Kit for Mouse Monocyte differentiation antigen CD14
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    CLIA Kit for Mouse Monocyte differentiation antigen CD14
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    U0685h
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    96T
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    CLIA Kit for Mouse Monocyte differentiation antigen CD14
    Cat.:
    U0685r
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Monocyte differentiation antigen CD14
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Monocyte differentiation antigen CD14
    Cat.:
    U0685b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Monocyte differentiation antigen CD14
    Cat.:
    U0685m
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Mouse Monocyte differentiation antigen CD14
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    P0685Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Monocyte differentiation antigen CD14
    Polyclonal Antibody for Mouse Monocyte differentiation antigen CD14
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    P0685Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Monocyte differentiation antigen CD14
    Cat.:
    P0685Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Monocyte differentiation antigen CD14
    Monoclonal Antibody for Mouse Monocyte differentiation antigen CD14
    Monoclonal Antibody for Mouse Monocyte differentiation antigen CD14
    Monoclonal Antibody for Mouse Monocyte differentiation antigen CD14
    Monoclonal Antibody for Mouse Monocyte differentiation antigen CD14
    Monoclonal Antibody for Mouse Monocyte differentiation antigen CD14
    Protein for Mouse Monocyte differentiation antigen CD14
    Protein for Mouse Monocyte differentiation antigen CD14
    Protein for Mouse Monocyte differentiation antigen CD14
    Protein for Mouse Monocyte differentiation antigen CD14
    Protein for Mouse Monocyte differentiation antigen CD14

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    Linearity
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    References
    1. 1.
      "Nucleotide and amino acid sequences of the mouse CD14 gene."
      Miyazaki Y. , Setoguchi M. , Yoshida S. , Higuchi Y. , Akizuki S. , Yamamoto S.
      Nucleic Acids Res.17:2132-2132(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: BALB/c.
      tissue: Liver.
    2. 2.
      "Mouse and human CD14 (myeloid cell-specific leucine-rich glycoprotein) primary structure deduced from cDNA clones."
      Setoguchi M. , Nasu N. , Yoshida S. , Higuchi Y. , Akizuki S. , Yamamoto S.
      Biochim. Biophys. Acta1008:213-222(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: ICR.
      tissue: Macrophage.
    3. 3.
      "CD14 is a member of the family of leucine-rich proteins and is encoded by a gene syntenic with multiple receptor genes."
      Ferrero E. , Hsieh C.L. , Francke U. , Goyert S.M.
      J. Immunol.145:331-336(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: NMRI.
      tissue: Mammary gland.
    5. 5.
      "Crystal structure of CD14 and its implications for lipopolysaccharide signaling."
      Kim J.I. , Lee C.J. , Jin M.S. , Lee C.H. , Paik S.G. , Lee H. , Lee J.O.
      J. Biol. Chem.280:11347-11351(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 20-329;DISULFIDE BONDS;GLYCOSYLATION AT ASN-147; ASN-180 AND ASN-276;DOMAINS LEUCINE-RICH REPEATS
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