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Index > Protein center > Cd180(Gene name) > Mouse
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  • Cd180 (Gene name),
  • CD180 antigen (Protein name ),  CD180_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Cd180(Ly78;Rp105);
    Protein name:
    CD180 antigen;
    Alternative:
    Radioprotective 105 kDa protein;Lymphocyte antigen 78(Ly-78);
    CD:
    CD180;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Binds to MD-1.
    Function:
    May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    661
    Sequence:
    50:
    MAPDISCFFL | VALFLASCRA | TTSSDQKCIE | KEVNKTYNCE | NLGLNEIPGT | 
    100:
    LPNSTECLEF | SFNVLPTIQN | TTFSRLINLT | FLDLTRCQIY | WIHEDTFQSQ | 
    150:
    HRLDTLVLTA | NPLIFMAETA | LSGPKALKHL | FFIQTGISSI | DFIPLHNQKT | 
    200:
    LESLYLGSNH | ISSIKLPKGF | PTEKLKVLDF | QNNAIHYLSK | EDMSSLQQAT | 
    250:
    NLSLNLNGND | IAGIELGAFD | SAVFQSLNFG | GTQNLLVIFK | GLKNSTIQSL | 
    300:
    WLGTFEDMDD | EDISPAVFEG | LCEMSVESIN | LQKHYFFNIS | SNTFHCFSGL | 
    350:
    QELDLTATHL | SELPSGLVGL | STLKKLVLSA | NKFENLCQIS | ASNFPSLTHL | 
    400:
    SIKGNTKRLE | LGTGCLENLE | NLRELDLSHD | DIETSDCCNL | QLRNLSHLQS | 
    450:
    LNLSYNEPLS | LKTEAFKECP | QLELLDLAFT | RLKVKDAQSP | FQNLHLLKVL | 
    500:
    NLSHSLLDIS | SEQLFDGLPA | LQHLNLQGNH | FPKGNIQKTN | SLQTLGRLEI | 
    550:
    LVLSFCDLSS | IDQHAFTSLK | MMNHVDLSHN | RLTSSSIEAL | SHLKGIYLNL | 
    600:
    ASNRISIILP | SLLPILSQQR | TINLRQNPLD | CTCSNIYFLE | WYKENMQKLE | 
    650:
    DTEDTLCENP | PLLRGVRLSD | VTLSCSMAAV | GIFFLIVFLL | VFAILLIFAV | 
    661:
    KYFLRWKYQH | I
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse CD180 antigen
    ELISA Kit for Mouse CD180 antigen
    CLIA Kit for Mouse CD180 antigen
    CLIA Kit for Mouse CD180 antigen
    Polyclonal Antibody for Mouse CD180 antigen
    Polyclonal Antibody for Mouse CD180 antigen
    Monoclonal Antibody for Mouse CD180 antigen
    Monoclonal Antibody for Mouse CD180 antigen
    Protein for Mouse CD180 antigen
    Protein for Mouse CD180 antigen

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "RP105, a novel B cell surface molecule implicated in B cell activation, is a member of the leucine-rich repeat protein family."
      Miyake K. , Yamashita Y. , Ogata M. , Sudo T. , Kimoto M.
      J. Immunol.154:3333-3340(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 21-43
      strain: BALB/c.
      tissue: B-cell lymphoma.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: NOD.
    3. 3.
      "Mouse MD-1, a molecule that is physically associated with RP105 and positively regulates its expression."
      Miyake K. , Shimazu R. , Kondo J. , Niki T. , Akashi S. , Ogata H. , Yamashita Y. , Miura Y. , Kimoto M.
      J. Immunol.161:1348-1353(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH LY86
    4. 4.
      "The Toll-like receptor protein RP105 regulates lipopolysaccharide signaling in B cells."
      Ogata H. , Su I. , Miyake K. , Nagai Y. , Akashi S. , Mecklenbraeuker I. , Rajewsky K. , Kimoto M. , Tarakhovsky A.
      J. Exp. Med.192:23-29(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    5. 5.
      "Crystal structures of mouse and human RP105/MD-1 complexes reveal unique dimer organization of the toll-like receptor family."
      Ohto U. , Miyake K. , Shimizu T.
      J. Mol. Biol.413:815-825(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 21-626 IN COMPLEX WITH LY86;SUBUNIT;GLYCOSYLATION AT ASN-34; ASN-53; ASN-70; ASN-244; ASN-394; ASN-402 AND ASN-451
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