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Index > Protein center > CD3G(Gene name) > Human
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  • CD3G (Gene name),
  • T-cell surface glycoprotein CD3 gamma chain (Protein name ),  CD3G_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CD3G(T3G);
    Protein name:
    T-cell surface glycoprotein CD3 gamma chain;
    Alternative:
    T-cell receptor T3 gamma chain;
    CD:
    CD3g;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta.
    Function:
    The CD3 complex mediates signal transduction.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    182
    Sequence:
    50:
    MEQGKGLAVL | ILAIILLQGT | LAQSIKGNHL | VKVYDYQEDG | SVLLTCDAEA | 
    100:
    KNITWFKDGK | MIGFLTEDKK | KWNLGSNAKD | PRGMYQCKGS | QNKSKPLQVY | 
    150:
    YRMCQNCIEL | NAATISGFLF | AEIVSIFVLA | VGVYFIAGQD | GVRQSRASDK | 
    182:
    QTLLPNDQLY | QPLKDREDDQ | YSHLQGNQLR | RN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    SMR:
    Pfam:
    MIM:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human T-cell surface glycoprotein CD3 gamma chain
    MSDS:
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    ELISA Kit for Human T-cell surface glycoprotein CD3 gamma chain
    Cat.:
    E10023h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human T-cell surface glycoprotein CD3 gamma chain
    Cat.:
    E10023m
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    Packing:
    96T
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    ELISA Kit for Human T-cell surface glycoprotein CD3 gamma chain
    Cat.:
    E10023r
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    96T
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    ELISA Kit for Human T-cell surface glycoprotein CD3 gamma chain
    MSDS:
    Please sign in first.
    CLIA Kit for Human T-cell surface glycoprotein CD3 gamma chain
    MSDS:
    Please sign in first.
    CLIA Kit for Human T-cell surface glycoprotein CD3 gamma chain
    Cat.:
    U10023m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human T-cell surface glycoprotein CD3 gamma chain
    Cat.:
    U10023r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human T-cell surface glycoprotein CD3 gamma chain
    MSDS:
    Please sign in first.
    CLIA Kit for Human T-cell surface glycoprotein CD3 gamma chain
    Cat.:
    U10023h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human T-cell surface glycoprotein CD3 gamma chain
    Polyclonal Antibody for Human T-cell surface glycoprotein CD3 gamma chain
    Cat.:
    P10023Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human T-cell surface glycoprotein CD3 gamma chain
    Polyclonal Antibody for Human T-cell surface glycoprotein CD3 gamma chain
    Polyclonal Antibody for Human T-cell surface glycoprotein CD3 gamma chain
    Monoclonal Antibody for Human T-cell surface glycoprotein CD3 gamma chain
    Monoclonal Antibody for Human T-cell surface glycoprotein CD3 gamma chain
    Monoclonal Antibody for Human T-cell surface glycoprotein CD3 gamma chain
    Monoclonal Antibody for Human T-cell surface glycoprotein CD3 gamma chain
    Monoclonal Antibody for Human T-cell surface glycoprotein CD3 gamma chain
    Protein for Human T-cell surface glycoprotein CD3 gamma chain
    Protein for Human T-cell surface glycoprotein CD3 gamma chain
    Protein for Human T-cell surface glycoprotein CD3 gamma chain
    Protein for Human T-cell surface glycoprotein CD3 gamma chain
    Protein for Human T-cell surface glycoprotein CD3 gamma chain

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Primary structure of the T3 gamma subunit of the T3/T cell antigen receptor complex deduced from cDNA sequences: evolution of the T3 gamma and delta subunits."
      Krissansen G.W. , Owen M.J. , Verbi W. , Crumpton M.J.
      EMBO J.5:1799-1808(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Physical linkage of three CD3 genes on human chromosome 11."
      Tunnacliffe A. , Buluwela L. , Rabbitts T.H.
      EMBO J.6:2953-2957(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      "Dephosphorylation of the human T lymphocyte CD3 antigen."
      Alexander D. , Goris J. , Marais R. , Rothbard J. , Merlevede W. , Crumpton M.J.
      Eur. J. Biochem.181:55-65(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 139-182;PHOSPHORYLATION AT SER-145 AND SER-148
    5. 5.
      "The human T3 gamma chain is phosphorylated at serine 126 in response to T lymphocyte activation."
      Davies A.A. , Cantrell D.A. , Hexham J.M. , Parker P.J. , Rothbard J. , Crumpton M.J.
      J. Biol. Chem.262:10918-10921(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-145 AND SER-148
    6. 6.
      "A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chains."
      Letourneur F. , Klausner R.D.
      Cell69:1143-1157(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF LEU-153; LEU-154; TYR-160 AND LEU-163
    7. 7.
      "Brief report: primary immunodeficiency caused by mutations in the gene encoding the CD3-gamma subunit of the T-lymphocyte receptor."
      Arnaiz-Villena A. , Timon M. , Corell A. , Perez-Aciego P. , Martin-Villa J.M. , Regueiro J.R.
      N. Engl. J. Med.327:529-533(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN IMD17
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN IMD17
    9. 9.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    10. 10.
      "Crystal structure of the human T cell receptor CD3 epsilon gamma heterodimer complexed to the therapeutic mAb OKT3."
      Kjer-Nielsen L. , Dunstone M.A. , Kostenko L. , Ely L.K. , Beddoe T. , Mifsud N.A. , Purcell A.W. , Brooks A.G. , McCluskey J. , Rossjohn J.
      Proc. Natl. Acad. Sci. U.S.A.101:7675-7680(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 23-103 IN COMPLEX WITH CD3E AND ANTIBODY;SUBUNIT;DISULFIDE BOND
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