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Index > Protein center > CD69(Gene name) > Human
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  • CD69 (Gene name),
  • Early activation antigen CD69 (Protein name ),  CD69_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    CD69(CLEC2C);
    Protein name:
    Early activation antigen CD69;
    Alternative:
    BL-AC/P26;Activation inducer molecule(AIM);EA1;C-type lectin domain family 2 member C;GP32/28;Early T-cell activation antigen p60;MLR-3;Leukocyte surface antigen Leu-23;
    CD:
    CD69;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer; disulfide-linked.
    Function:
    Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.
    Subcellular Location:
    Membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    199
    Sequence:
    50:
    MSSENCFVAE | NSSLHPESGQ | ENDATSPHFS | TRHEGSFQVP | VLCAVMNVVF | 
    100:
    ITILIIALIA | LSVGQYNCPG | QYTFSMPSDS | HVSSCSEDWV | GYQRKCYFIS | 
    150:
    TVKRSWTSAQ | NACSEHGATL | AVIDSEKDMN | FLKRYAGREE | HWVGLKKEPG | 
    199:
    HPWKWSNGKE | FNNWFNVTGS | DKCVFLKNTE | VSSMECEKNL | YWICNKPYK
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    Pfam:
    String:
    KEGG:
    MIM:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Early activation antigen CD69
    Cat.:
    E1153h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Early activation antigen CD69
    Cat.:
    E1153m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Early activation antigen CD69
    Cat.:
    U1153m
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Early activation antigen CD69
    Cat.:
    U1153h
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Early activation antigen CD69
    Cat.:
    P1153Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Early activation antigen CD69
    Cat.:
    P1153Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Early activation antigen CD69
    Monoclonal Antibody for Human Early activation antigen CD69
    Protein for Human Early activation antigen CD69
    Protein for Human Early activation antigen CD69

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Expression cloning of the early activation antigen CD69, a type II integral membrane protein with a C-type lectin domain."
      Hamann J. , Fiebig H. , Strauss M.
      J. Immunol.150:4920-4927(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Blood.
    2. 2.
      "Molecular cloning, expression, and chromosomal localization of the human earliest lymphocyte activation antigen AIM/CD69, a new member of the C-type animal lectin superfamily of signal-transmitting receptors."
      Lopez-Cabrera M. , Santis A.G. , Fernandez-Ruiz E. , Blacher R. , Esch F. , Sanchez-Mateos P. , Sanchez-Madrid F.
      J. Exp. Med.178:537-547(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 96-103; 128-146 AND 189-199
      tissue: Blood.
    3. 3.
      "Molecular characterization of the early activation antigen CD69: a type II membrane glycoprotein related to a family of natural killer cell activation antigens."
      Ziegler S.F. , Ramsdell F. , Hjerrild K.A. , Armitage R.J. , Grabstein K.H. , Hennen K.B. , Farrah T. , Fanslow W.C. , Shevach E.M. , Alderson M.R.
      Eur. J. Immunol.23:1643-1648(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      "Structure of the gene coding for the human early lymphocyte activation antigen CD69: a C-type lectin receptor evolutionarily related with the gene families of natural killer cell-specific receptors."
      Santis A. , Lopez-Cabrera M. , Hamann J. , Strauss M. , Sanchez-Madrid F.
      Eur. J. Immunol.24:1692-1697(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Placenta.
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Pancreas.
    6. 6.
      "Crystal structure of human CD69: a C-type lectin-like activation marker of hematopoietic cells."
      Natarajan K. , Sawicki M.W. , Margulies D.H. , Mariuzza R.A.
      Biochemistry39:14779-14786(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.27 ANGSTROMS);SUBUNIT;DISULFIDE BONDS
    7. 7.
      "Crystal structure of the C-type lectin-like domain from the human hematopoietic cell receptor CD69."
      Llera A.S. , Viedma F. , Sanchez-Madrid F. , Tormo J.
      J. Biol. Chem.276:7312-7319(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.5 ANGSTROMS) OF 82-199;SUBUNIT;DISULFIDE BONDS
    8. 8.
      "Soluble recombinant CD69 receptors optimized to have an exceptional physical and chemical stability display prolonged circulation and remain intact in the blood of mice."
      Vanek O. , Nalezkova M. , Kavan D. , Borovickova I. , Pompach P. , Novak P. , Kumar V. , Vannucci L. , Hudecek J. , Hofbauerova K. , Kopecky V. Jr. , Brynda J. , Kolenko P. , Dohnalek J. , Kaderavek P. , Chmelik J. , Gorcik L. , Zidek L. , more...
      FEBS J.275:5589-5606(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) OF 82-199;SUBUNIT;DISULFIDE BONDS
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