Protein name:
Cell division cycle protein 20 homolog ;
Alternative:
p55CDC ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Found in a complex with CDC20, CDC27, SPATC1 and TUBG1. Interacts with MAD2L1, BUB1B and SPATC1. The phosphorylated form interacts with APC/C. Interacts with NINL and MAD2L1 (By similarity). Interacts with CDK5RAP2. Interacts with NEUROD2.
Function:
Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1. In metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation (By similarity). Interacts with NEK2.
Subcellular Location:
Cytoplasm
cytoskeleton
centrosome
Cytoplasm
cytoskeleton
spindle pole
Protein Attributes:
50:
MAQFVFESDL | HSLLQLDAPI | PNAPIARWQR | KAKEATGPAP | SPMRAANRSH |
100:
SAGRTPGRTP | GKSNSKVQTT | PSKPGGDRYI | PQRSASQMEV | ASFLLSKENQ |
150:
PEDGGTPTKK | EHQKAWARNL | NGFDVEEAKI | LRLSGKPQNA | PEGYQNRLKV |
200:
LYSQKATPGS | SRKACRYIPS | LPDRILDAPE | IRNDYYLNLV | DWSSGNVLAV |
250:
ALDNSVYLWN | AGSGDILQLL | QMEQPGDYIS | SVAWIKEGNY | LAVGTSNAEV |
300:
QLWDVQQQKR | LRNMTSHSAR | VSSLSWNSYI | LSSGSRSGHI | HHHDVRVAEH |
350:
HVATLSGHSQ | EVCGLRWAPD | GRHLASGGND | NIVNVWPSGP | GESGWVPLQT |
400:
FTQHQGAVKA | VAWCPWQSNI | LATGGGTSDR | HIRIWNVCSG | ACLSAVDVHS |
450:
QVCSILWSPH | YKELISGHGF | AQNQLVIWKY | PTMAKVAELK | GHTARVLSLT |
499:
MSPDGATVAS | AAADETLRLW | RCFELDPALR | REREKASTSK | SSLIHQGIR
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Pig
Mouse
Rat
ELISA Kit for Rat Cell division cycle protein 20 homolog
ELISA Kit for Rat Cell division cycle protein 20 homolog
ELISA Kit for Rat Cell division cycle protein 20 homolog
ELISA Kit for Rat Cell division cycle protein 20 homolog
CLIA Kit for Rat Cell division cycle protein 20 homolog
CLIA Kit for Rat Cell division cycle protein 20 homolog
CLIA Kit for Rat Cell division cycle protein 20 homolog
CLIA Kit for Rat Cell division cycle protein 20 homolog
Polyclonal Antibody for Rat Cell division cycle protein 20 homolog
Polyclonal Antibody for Rat Cell division cycle protein 20 homolog
Polyclonal Antibody for Rat Cell division cycle protein 20 homolog
Polyclonal Antibody for Rat Cell division cycle protein 20 homolog
Monoclonal Antibody for Rat Cell division cycle protein 20 homolog
Monoclonal Antibody for Rat Cell division cycle protein 20 homolog
Monoclonal Antibody for Rat Cell division cycle protein 20 homolog
Monoclonal Antibody for Rat Cell division cycle protein 20 homolog
Protein for Rat Cell division cycle protein 20 homolog
Protein for Rat Cell division cycle protein 20 homolog
Protein for Rat Cell division cycle protein 20 homolog
Protein for Rat Cell division cycle protein 20 homolog
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Spleen .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Testis .